In [1]:
# aim: to retrieve compounds from chembl tested against a target
# starting point: UNIPROT ID of target (from e.g. www.rcsb.org)
In [2]:
# some general settngs
import json
import warnings
import logging
In [3]:
# loading chembl package, creating chembl client
import chembl_webresource_client
from chembl_webresource_client import *
from chembl_webresource_client.settings import Settings
from chembl_webresource_client.new_client import new_client as chembl
In [4]:
chembl.target.set_format('json')
In [5]:
# step 1: finding CHEMBL id of target
# we poke a bit around in the data structure
print(dir(chembl))
print(chembl.target)
print(chembl.target[0]['target_components'][0]['accession'] )

['__class__', '__delattr__', '__dict__', '__dir__', '__doc__', '__eq__', '__format__', '__ge__', '__getattribute__', '__gt__', '__hash__', '__init__', '__init_subclass__', '__le__', '__lt__', '__module__', '__ne__', '__new__', '__reduce__', '__reduce_ex__', '__repr__', '__setattr__', '__sizeof__', '__str__', '__subclasshook__', '__weakref__', 'activity', 'assay', 'atc_class', 'binding_site', 'biotherapeutic', 'cell_line', 'chembl_id_lookup', 'compound_record', 'compound_structural_alert', 'description', 'document', 'document_similarity', 'document_term', 'drug', 'drug_indication', 'go_slim', 'image', 'mechanism', 'metabolism', 'molecule', 'molecule_form', 'official', 'organism', 'protein_class', 'similarity', 'source', 'substructure', 'target', 'target_component', 'target_prediction', 'target_relation', 'tissue', 'xref_source']
[{'cross_references': [{'xref_id': 'O43451', 'xref_name': None, 'xref_src': 'canSAR-Target'}, {'xref_id': 'Maltase-glucoamylase', 'xref_name': None, 'xref_src': 'Wikipedia'}], 'organism': 'Homo sapiens', 'pref_name': 'Maltase-glucoamylase', 'species_group_flag': False, 'target_chembl_id': 'CHEMBL2074', 'target_components': [{'accession': 'O43451', 'component_description': 'Maltase-glucoamylase, intestinal', 'component_id': 434, 'component_type': 'PROTEIN', 'relationship': 'SINGLE PROTEIN', 'target_component_synonyms': [{'component_synonym': 'MGA ', 'syn_type': 'GENE_SYMBOL'}, {'component_synonym': 'MGAML', 'syn_type': 'GENE_SYMBOL'}, {'component_synonym': 'MGAM', 'syn_type': 'GENE_SYMBOL'}, {'component_synonym': 'Maltase-glucoamylase, intestinal', 'syn_type': 'UNIPROT'}, {'component_synonym': 'Maltase', 'syn_type': 'UNIPROT'}, {'component_synonym': 'Glucoamylase', 'syn_type': 'UNIPROT'}, {'component_synonym': 'Alpha-glucosidase', 'syn_type': 'UNIPROT'}, {'component_synonym': 'Glucan 1,4-alpha-glucosidase', 'syn_type': 'UNIPROT'}, {'component_synonym': '3.2.1.20', 'syn_type': 'EC_NUMBER'}, {'component_synonym': '3.2.1.3', 'syn_type': 'EC_NUMBER'}]}], 'target_type': 'SINGLE PROTEIN', 'tax_id': 9606}, {'cross_references': [{'xref_id': 'O60706', 'xref_name': None, 'xref_src': 'canSAR-Target'}, {'xref_id': 'ABCC9', 'xref_name': None, 'xref_src': 'Wikipedia'}], 'organism': 'Homo sapiens', 'pref_name': 'Sulfonylurea receptor 2', 'species_group_flag': False, 'target_chembl_id': 'CHEMBL1971', 'target_components': [{'accession': 'O60706', 'component_description': 'ATP-binding cassette sub-family C member 9', 'component_id': 294, 'component_type': 'PROTEIN', 'relationship': 'SINGLE PROTEIN', 'target_component_synonyms': [{'component_synonym': 'SUR2', 'syn_type': 'GENE_SYMBOL'}, {'component_synonym': 'ABCC9', 'syn_type': 'GENE_SYMBOL'}, {'component_synonym': 'ATP-binding cassette sub-family C member 9', 'syn_type': 'UNIPROT'}, {'component_synonym': 'Sulfonylurea receptor 2', 'syn_type': 'UNIPROT'}]}], 'target_type': 'SINGLE PROTEIN', 'tax_id': 9606}, {'cross_references': [{'xref_id': 'CGMP-specific_phosphodiesterase_type_5', 'xref_name': None, 'xref_src': 'Wikipedia'}], 'organism': 'Homo sapiens', 'pref_name': 'Phosphodiesterase 5A', 'species_group_flag': False, 'target_chembl_id': 'CHEMBL1827', 'target_components': [{'accession': 'O76074', 'component_description': "cGMP-specific 3',5'-cyclic phosphodiesterase", 'component_id': 124, 'component_type': 'PROTEIN', 'relationship': 'SINGLE PROTEIN', 'target_component_synonyms': [{'component_synonym': 'PDE5', 'syn_type': 'GENE_SYMBOL'}, {'component_synonym': 'PDE5A', 'syn_type': 'GENE_SYMBOL'}, {'component_synonym': "cGMP-specific 3',5'-cyclic phosphodiesterase", 'syn_type': 'UNIPROT'}, {'component_synonym': 'cGMP-binding cGMP-specific phosphodiesterase', 'syn_type': 'UNIPROT'}, {'component_synonym': 'CGB-PDE', 'syn_type': 'UNIPROT'}, {'component_synonym': '3.1.4.35', 'syn_type': 'EC_NUMBER'}]}], 'target_type': 'SINGLE PROTEIN', 'tax_id': 9606}, {'cross_references': [{'xref_id': 'O95180', 'xref_name': None, 'xref_src': 'canSAR-Target'}, {'xref_id': 'CACNA1H', 'xref_name': None, 'xref_src': 'Wikipedia'}], 'organism': 'Homo sapiens', 'pref_name': 'Voltage-gated T-type calcium channel alpha-1H subunit', 'species_group_flag': False, 'target_chembl_id': 'CHEMBL1859', 'target_components': [{'accession': 'O95180', 'component_description': 'Voltage-dependent T-type calcium channel subunit alpha-1H', 'component_id': 167, 'component_type': 'PROTEIN', 'relationship': 'SINGLE PROTEIN', 'target_component_synonyms': [{'component_synonym': 'CACNA1H', 'syn_type': 'GENE_SYMBOL'}, {'component_synonym': 'Voltage-dependent T-type calcium channel subunit alpha-1H', 'syn_type': 'UNIPROT'}, {'component_synonym': 'Low-voltage-activated calcium channel alpha1 3.2 subunit', 'syn_type': 'UNIPROT'}, {'component_synonym': 'Voltage-gated calcium channel subunit alpha Cav3.2', 'syn_type': 'UNIPROT'}]}], 'target_type': 'SINGLE PROTEIN', 'tax_id': 9606}, '...(remaining elements truncated)...']
O43451
In [6]:
# step 2: we search chembl.target list for items that have our 
# uniprot code in chembl.target[]['target_components'][0]['accession'] dictionary
ABL_kinase_uniprotID =  "P42684"
print(ABL_kinase_uniprotID)
chembl_abl_candidates = []
errorcount = 0
for i in range(len(chembl.target)):
    try:
        if chembl.target[i]['target_components'][0]['accession'] ==  ABL_kinase_uniprotID:
            chembl_abl_candidates.append(chembl.target[i])
    except:
        errorcount += 1
print(len(chembl_abl_candidates))    
print(chembl_abl_candidates[0]['target_components'][0]['component_description'],
      chembl_abl_candidates[0]['target_chembl_id'] )

print("for " + str(errorcount) + " targets no accession id was found")        
          

P42684
1
Abelson tyrosine-protein kinase 2 CHEMBL4014
for 4099 targets no accession id was found
In [7]:
# bingo, the component maescription matches, we have found our CHEMBL id
# this code snippet does a similar job, but returns the CHEMBL id for the ABL family of enzymes as well
chembl_abl_candidates_alt = chembl.target.filter(target_components__accession=ABL_kinase_uniprotID)
print ([(x['target_chembl_id'], x['pref_name']) for x in chembl_abl_candidates_alt])

[('CHEMBL4014', 'Tyrosine-protein kinase ABL2'), ('CHEMBL2111414', 'Tyrosine-protein kinase ABL')]
In [8]:
print(chembl.activity)

[{'activity_comment': None, 'activity_id': 31863, 'assay_chembl_id': 'CHEMBL663853', 'assay_description': 'Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322; no measurable activity', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'o1c(nc2c(cccc12)c3oc4ccccc4n3)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1137930', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2004, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL113081', 'parent_molecule_chembl_id': 'CHEMBL113081', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '100', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 206172, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '100000', 'target_chembl_id': 'CHEMBL1806', 'target_organism': 'Homo sapiens', 'target_pref_name': 'DNA topoisomerase II alpha', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 31864, 'assay_chembl_id': 'CHEMBL872937', 'assay_description': 'In vivo inhibitory activity against human Heparanase', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000218', 'bao_label': 'organism-based format', 'canonical_smiles': 'Cc1ccc2oc(nc2c1)c3cccc(c3)N4C(=O)c5ccc(cc5C4=O)C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1146658', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2004, 'ligand_efficiency': {'bei': '14.06', 'le': '0.26', 'lle': '1.59', 'sei': '5.56'}, 'molecule_chembl_id': 'CHEMBL324340', 'parent_molecule_chembl_id': 'CHEMBL324340', 'pchembl_value': '5.6', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '2.5', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 208970, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '2500', 'target_chembl_id': 'CHEMBL3921', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Heparanase', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 31865, 'assay_chembl_id': 'CHEMBL693237', 'assay_description': 'In vivo concentration required against angiogenesis in human endothelial cells', 'assay_type': 'F', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000218', 'bao_label': 'organism-based format', 'canonical_smiles': 'Cc1ccc2oc(nc2c1)c3cccc(c3)N4C(=O)c5ccc(cc5C4=O)C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1146658', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2004, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL324340', 'parent_molecule_chembl_id': 'CHEMBL324340', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '50', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 208970, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '50000', 'target_chembl_id': 'CHEMBL612545', 'target_organism': None, 'target_pref_name': 'Unchecked', 'target_tax_id': None, 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 31866, 'assay_chembl_id': 'CHEMBL872937', 'assay_description': 'In vivo inhibitory activity against human Heparanase', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000218', 'bao_label': 'organism-based format', 'canonical_smiles': 'COc1ccc(cc1N2C(=O)c3ccc(cc3C2=O)C(=O)O)c4oc5ccc(cc5n4)c6ccccc6OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1146658', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2004, 'ligand_efficiency': {'bei': '9.69', 'le': '0.18', 'lle': '0.04', 'sei': '4.23'}, 'molecule_chembl_id': 'CHEMBL109600', 'parent_molecule_chembl_id': 'CHEMBL109600', 'pchembl_value': '5.05', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '9', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 208987, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '9000', 'target_chembl_id': 'CHEMBL3921', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Heparanase', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, '...(remaining elements truncated)...']
In [9]:
# Let's get all measurement for a target
chembl_abl_activities = chembl.activity.filter(target_chembl_id='CHEMBL4014')
print(list(chembl_abl_activities))

[{'activity_comment': 'Not Active', 'activity_id': 1650414, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL554', 'parent_molecule_chembl_id': 'CHEMBL554', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405809, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 1650415, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\\C=C\\CN(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '14.52', 'le': '0.28', 'lle': '2.34', 'sei': '7.53'}, 'molecule_chembl_id': 'CHEMBL607707', 'parent_molecule_chembl_id': 'CHEMBL607707', 'pchembl_value': '6.8', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '0.16', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405810, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '160', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Active', 'activity_id': 1650416, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(Nc2nnc(Cc3ccncc3)c4ccccc24)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL101253', 'parent_molecule_chembl_id': 'CHEMBL101253', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405812, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 1650417, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCNC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccc(F)cc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '14.86', 'le': '0.28', 'lle': '2.92', 'sei': '7.67'}, 'molecule_chembl_id': 'CHEMBL535', 'parent_molecule_chembl_id': 'CHEMBL535', 'pchembl_value': '5.92', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '1.2', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405813, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1200', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Active', 'activity_id': 1650418, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(ncnc2cc1OCCCN3CCCCC3)N4CCN(CC4)C(=O)Nc5ccc(OC(C)C)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL124660', 'parent_molecule_chembl_id': 'CHEMBL124660', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405814, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 1650419, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c4cn(CCO1)c5ccccc45)c6ccccc26', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL91829', 'parent_molecule_chembl_id': 'CHEMBL91829', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405815, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 1650420, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '12.66', 'le': '0.25', 'lle': '1.71', 'sei': '6.37'}, 'molecule_chembl_id': 'CHEMBL1336', 'parent_molecule_chembl_id': 'CHEMBL1336', 'pchembl_value': '5.89', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '1.3', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405816, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1300', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Active', 'activity_id': 1650421, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL14762', 'parent_molecule_chembl_id': 'CHEMBL14762', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405817, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 1650422, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CC[C@@H]([C@H](O)C1)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccccc4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL428690', 'parent_molecule_chembl_id': 'CHEMBL428690', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405818, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 1651258, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '14.57', 'le': '0.27', 'lle': '2.98', 'sei': '9.79'}, 'molecule_chembl_id': 'CHEMBL388978', 'parent_molecule_chembl_id': 'CHEMBL388978', 'pchembl_value': '6.8', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '0.16', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405819, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '160', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Active', 'activity_id': 1651259, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL278041', 'parent_molecule_chembl_id': 'CHEMBL278041', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405800, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 1651260, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[S+]([O-])c1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL10', 'parent_molecule_chembl_id': 'CHEMBL10', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405801, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 1651261, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(SC2=NN3C=NC(=O)C(=C3C=C2)c4c(Cl)cccc4Cl)c(F)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '15.26', 'le': '0.32', 'lle': '1.32', 'sei': '9.47'}, 'molecule_chembl_id': 'CHEMBL119385', 'parent_molecule_chembl_id': 'CHEMBL119385', 'pchembl_value': '6.66', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '0.22', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405802, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '220', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Active', 'activity_id': 1651262, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1)n2nc(cc2NC(=O)Nc3ccc(OCCN4CCOCC4)c5ccccc35)C(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103667', 'parent_molecule_chembl_id': 'CHEMBL103667', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405803, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 1651263, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c2ccccc2c3N=Nc4cccc1c34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1725279', 'parent_molecule_chembl_id': 'CHEMBL1725279', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405804, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 1651264, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '15.98', 'le': '0.29', 'lle': '3.67', 'sei': '9.14'}, 'molecule_chembl_id': 'CHEMBL941', 'parent_molecule_chembl_id': 'CHEMBL941', 'pchembl_value': '7.89', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '0.013', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405805, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Active', 'activity_id': 1651265, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL939', 'parent_molecule_chembl_id': 'CHEMBL939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Kd', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 405806, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Kd', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 1651266, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '16.58', 'le': '0.31', 'lle': '2.21', 'sei': '8.73'}, 'molecule_chembl_id': 'CHEMBL553', 'parent_molecule_chembl_id': 'CHEMBL553', 'pchembl_value': '6.52', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '0.3', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405807, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '300', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 1651267, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC4CCN(C)CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '14.49', 'le': '0.31', 'lle': '1.8', 'sei': '11.57'}, 'molecule_chembl_id': 'CHEMBL24828', 'parent_molecule_chembl_id': 'CHEMBL24828', 'pchembl_value': '6.89', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '0.13', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405811, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '130', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 1651268, 'assay_chembl_id': 'CHEMBL860899', 'assay_description': 'Average Binding Constant for ABL2; NA=Not Active at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1144455', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2005, 'ligand_efficiency': {'bei': '12.11', 'le': '0.24', 'lle': '1.85', 'sei': '6.64'}, 'molecule_chembl_id': 'CHEMBL31965', 'parent_molecule_chembl_id': 'CHEMBL31965', 'pchembl_value': '5.89', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '1.3', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 405808, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1300', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 1727535, 'assay_chembl_id': 'CHEMBL859731', 'assay_description': 'Inhibition of human Arg kinase at 3 uM in presence of 10 uM ATP', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1OC)C(=O)Nc2sc3CCCCc3c2C(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1147807', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2006, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL210833', 'parent_molecule_chembl_id': 'CHEMBL210833', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 481621, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 1769377, 'assay_chembl_id': 'CHEMBL910897', 'assay_description': 'Inhibition of Arg kinase', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H]1C[C@H]2CN1CCn3nc4c(cccc4c3O)c5nc6c(O2)cccc6nc5O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1149510', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2006, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL215803', 'parent_molecule_chembl_id': 'CHEMBL215803', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '1', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 582040, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '1000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2050261, 'assay_chembl_id': 'CHEMBL925559', 'assay_description': 'Inhibition of Arg at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1CCN(CC1)c2ccc(CO)cc2NC(=O)c3oc(cc3)C#N', 'data_validity_comment': 'Values for this activity type are unusually large/small, so may not be accurate', 'document_chembl_id': 'CHEMBL1140541', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2007, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL400754', 'parent_molecule_chembl_id': 'CHEMBL400754', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 680458, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2147190, 'assay_chembl_id': 'CHEMBL927934', 'assay_description': 'Activity of human Arg kinase at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4c3n2)c5c(F)cccc5F)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1147076', 'document_journal': 'Proc. Natl. Acad. Sci. U.S.A.', 'document_year': 2007, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL259084', 'parent_molecule_chembl_id': 'CHEMBL259084', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '40', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 709269, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '40', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2470095, 'assay_chembl_id': 'CHEMBL1032237', 'assay_description': 'Inhibition of ABL2 at 3 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCOc1cc(ccc1NC(=O)C2COc3ccccc3O2)c4cn[nH]c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1142492', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL521179', 'parent_molecule_chembl_id': 'CHEMBL521179', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '10', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 801785, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2476602, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL257167', 'parent_molecule_chembl_id': 'CHEMBL257167', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '13.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 799523, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '13.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': 'Not Evaluated', 'activity_id': 2476805, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc(cc1)c2cc(C(=O)N)c(N)c(c2)c3ccc(cc3)S(=O)(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514582', 'parent_molecule_chembl_id': 'CHEMBL514582', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799524, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Evaluated', 'activity_id': 2478644, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1sc2CCCCc2c1C#N)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL233000', 'parent_molecule_chembl_id': 'CHEMBL233000', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799606, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Evaluated', 'activity_id': 2478847, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccccc2/C/1=C/c3ccc[nH]3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL86755', 'parent_molecule_chembl_id': 'CHEMBL86755', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799607, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 2479553, 'assay_chembl_id': 'CHEMBL988945', 'assay_description': 'Binding affinity to human ARG', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'c1ccc(nc1)c2n[nH]cc2c3ccnc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': {'bei': '21.04', 'le': '0.37', 'lle': '2.53', 'sei': '10.52'}, 'molecule_chembl_id': 'CHEMBL261454', 'parent_molecule_chembl_id': 'CHEMBL261454', 'pchembl_value': '5.73', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1870', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 799705, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1870', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Evaluated', 'activity_id': 2479702, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1c[nH]c2ncc(cc12)c3ccc(cc3)C#N)c4cccnc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL516312', 'parent_molecule_chembl_id': 'CHEMBL516312', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799522, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 2480701, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)Nc1ccc2NC(=O)\\C(=C(/Nc3ccc(CN4CCCCC4)cc3)\\c5ccccc5)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514409', 'parent_molecule_chembl_id': 'CHEMBL514409', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '4.8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 799608, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '4.8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2526443, 'assay_chembl_id': 'CHEMBL981439', 'assay_description': 'Binding affinity to Abl2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(Sc4ccc(NC(=O)C5CC5)cc4)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1154007', 'document_journal': 'J. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': {'bei': '18.08', 'le': '0.35', 'lle': '3.95', 'sei': '6.59'}, 'molecule_chembl_id': 'CHEMBL572878', 'parent_molecule_chembl_id': 'CHEMBL572878', 'pchembl_value': '8.4', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '4', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 808200, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Evaluated', 'activity_id': 2577323, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)c1c(C)c([nH]c1c2ccncc2)c3ccncc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL526901', 'parent_molecule_chembl_id': 'CHEMBL526901', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799787, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Evaluated', 'activity_id': 2577526, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc(Nc2cc([nH]n2)c3ccc(F)cc3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL511337', 'parent_molecule_chembl_id': 'CHEMBL511337', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799788, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Active', 'activity_id': 2593528, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(Sc4ccc(NC(=O)C5CC5)cc4)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL572878', 'parent_molecule_chembl_id': 'CHEMBL572878', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799609, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Active', 'activity_id': 2593731, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(O)cc1Nc2ccnc(Nc3cccc(c3)C(=O)N)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL249097', 'parent_molecule_chembl_id': 'CHEMBL249097', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799610, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 2593997, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2c1c(cn2C3CCNCC3)c4cccc(O)c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL450519', 'parent_molecule_chembl_id': 'CHEMBL450519', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '0.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 799789, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '0.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': 'Not Evaluated', 'activity_id': 2594940, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1c2ccc(cc2)C(=O)NCC3CC3)C(=O)NC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL478649', 'parent_molecule_chembl_id': 'CHEMBL478649', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799701, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Evaluated', 'activity_id': 2595143, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2cccc(c2)N3CCCCC3)cc1c4ccc(cc4)C(=O)NCC5CC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1964275', 'parent_molecule_chembl_id': 'CHEMBL1964275', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 799702, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 2595209, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1c2ccc(cc2)C(=O)NCC3CC3)C(=O)Nc4cccc(c4)C(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL515466', 'parent_molecule_chembl_id': 'CHEMBL515466', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '15.8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 799790, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '15.8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2596340, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1ccc(cc1)c2cc3ncccc3c(NCCCCN)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL282342', 'parent_molecule_chembl_id': 'CHEMBL282342', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '0.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 799703, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '0.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2597609, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cccc(c1)c2ccc3c(NC(=O)C4CC4)n[nH]c3n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL408019', 'parent_molecule_chembl_id': 'CHEMBL408019', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '4.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 799704, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '4.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2597812, 'assay_chembl_id': 'CHEMBL1035866', 'assay_description': 'Binding affinity to human ARG at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'c1ccc(nc1)c2n[nH]cc2c3ccnc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1151712', 'document_journal': 'J. Med. Chem.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261454', 'parent_molecule_chembl_id': 'CHEMBL261454', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '1.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 799705, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '1.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2721550, 'assay_chembl_id': 'CHEMBL1060958', 'assay_description': 'Inhibition of Arg at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)c2cnc3ccccn23)c4ccc(CNC(C)(C)C)cc4OC(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1154027', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL551079', 'parent_molecule_chembl_id': 'CHEMBL551079', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 830551, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2895505, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)c3cccc4[nH]nc(N)c34)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL223360', 'parent_molecule_chembl_id': 'CHEMBL223360', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845283, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895506, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1(C)CNc2cc(NC(=O)c3cccnc3NCc4ccncc4)ccc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL572881', 'parent_molecule_chembl_id': 'CHEMBL572881', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845284, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895507, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '15.99', 'le': '0.3', 'lle': '3.96', 'sei': '8.95'}, 'molecule_chembl_id': 'CHEMBL574738', 'parent_molecule_chembl_id': 'CHEMBL574738', 'pchembl_value': '8.47', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '3.4', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845285, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '3.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895508, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL215152', 'parent_molecule_chembl_id': 'CHEMBL215152', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845286, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895509, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1)n2nc(cc2NC(=O)Nc3ccc(OCCN4CCOCC4)c5ccccc35)C(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103667', 'parent_molecule_chembl_id': 'CHEMBL103667', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845287, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895510, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1oc(CSc2cnc(NC(=O)C3CCNCC3)s2)nc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL296468', 'parent_molecule_chembl_id': 'CHEMBL296468', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845288, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895511, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc3nc([nH]c3c2)C4=C(N)c5c(F)cccc5NC4=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL522892', 'parent_molecule_chembl_id': 'CHEMBL522892', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845289, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895512, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1c(Nc2ccc(cc2)C(F)(F)F)nc3cc(Oc4ccnc(c4)c5ncc([nH]5)C(F)(F)F)ccc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '11.04', 'le': '0.21', 'lle': '-0.75', 'sei': '7.09'}, 'molecule_chembl_id': 'CHEMBL558752', 'parent_molecule_chembl_id': 'CHEMBL558752', 'pchembl_value': '5.72', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1900', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845290, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1900', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895513, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '12.47', 'le': '0.24', 'lle': '2.02', 'sei': '6.84'}, 'molecule_chembl_id': 'CHEMBL31965', 'parent_molecule_chembl_id': 'CHEMBL31965', 'pchembl_value': '6.06', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '870', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845291, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '870', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895514, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H]1CCN(C[C@@H]1N(C)c2ncnc3[nH]ccc23)C(=O)CC#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL221959', 'parent_molecule_chembl_id': 'CHEMBL221959', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845292, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895515, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COCC(=O)NC\\C=C\\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL483321', 'parent_molecule_chembl_id': 'CHEMBL483321', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845293, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895516, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1nc(Nc2ncc(s2)C(=O)Nc3c(C)cccc3Cl)cc(n1)N4CCN(CCO)CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '20.02', 'le': '0.4', 'lle': '6.33', 'sei': '7.25'}, 'molecule_chembl_id': 'CHEMBL1421', 'parent_molecule_chembl_id': 'CHEMBL1421', 'pchembl_value': '9.77', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '0.17', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845294, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '0.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895517, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\\C=C\\CN(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '13.75', 'le': '0.27', 'lle': '1.97', 'sei': '7.12'}, 'molecule_chembl_id': 'CHEMBL607707', 'parent_molecule_chembl_id': 'CHEMBL607707', 'pchembl_value': '6.43', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '370', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845295, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '370', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895518, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '17.03', 'le': '0.32', 'lle': '2.39', 'sei': '8.96'}, 'molecule_chembl_id': 'CHEMBL553', 'parent_molecule_chembl_id': 'CHEMBL553', 'pchembl_value': '6.7', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '200', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845296, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '200', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895519, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CC[C@@H]([C@H](O)C1)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccccc4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL428690', 'parent_molecule_chembl_id': 'CHEMBL428690', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845297, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895520, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL939', 'parent_molecule_chembl_id': 'CHEMBL939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845298, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895521, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261849', 'parent_molecule_chembl_id': 'CHEMBL261849', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845299, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895522, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(c1ccc2c(C)n(C)nc2c1)c3ccnc(Nc4ccc(C)c(c4)S(=O)(=O)N)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '12.62', 'le': '0.24', 'lle': '1.78', 'sei': '4.34'}, 'molecule_chembl_id': 'CHEMBL477772', 'parent_molecule_chembl_id': 'CHEMBL477772', 'pchembl_value': '5.52', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '3000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845300, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '3000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895523, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '16.21', 'le': '0.3', 'lle': '3.78', 'sei': '9.27'}, 'molecule_chembl_id': 'CHEMBL941', 'parent_molecule_chembl_id': 'CHEMBL941', 'pchembl_value': '8', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845301, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895524, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(Nc2ccc(cc2)S(=O)(=O)N)nn1C(=O)c3c(F)cccc3F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191003', 'parent_molecule_chembl_id': 'CHEMBL191003', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845302, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895525, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL554', 'parent_molecule_chembl_id': 'CHEMBL554', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845303, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895526, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c4cn(CCO1)c5ccccc45)c6ccccc26', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL91829', 'parent_molecule_chembl_id': 'CHEMBL91829', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845304, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895527, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(ncnc2cc1OCCCN3CCCCC3)N4CCN(CC4)C(=O)Nc5ccc(OC(C)C)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL124660', 'parent_molecule_chembl_id': 'CHEMBL124660', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845305, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895528, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4c3n2)c5c(F)cccc5F)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '11.49', 'le': '0.22', 'lle': '-0.71', 'sei': '6.27'}, 'molecule_chembl_id': 'CHEMBL259084', 'parent_molecule_chembl_id': 'CHEMBL259084', 'pchembl_value': '5.48', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '3300', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845306, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '3300', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895529, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cccc(c1)c2nc(N3CCOCC3)c4oc5ncccc5c4n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL573339', 'parent_molecule_chembl_id': 'CHEMBL573339', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845307, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895530, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35)N(C)C(=O)c9ccccc9', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL608533', 'parent_molecule_chembl_id': 'CHEMBL608533', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845308, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895531, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(Nc2nnc(Cc3ccncc3)c4ccccc24)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL101253', 'parent_molecule_chembl_id': 'CHEMBL101253', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845309, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895532, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL14762', 'parent_molecule_chembl_id': 'CHEMBL14762', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845310, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895533, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL278041', 'parent_molecule_chembl_id': 'CHEMBL278041', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845311, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895534, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[S+]([O-])c1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL10', 'parent_molecule_chembl_id': 'CHEMBL10', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845312, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895535, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc(cc1)c2nc(c3ccccn3)c([nH]2)c4ccc5OCOc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL440084', 'parent_molecule_chembl_id': 'CHEMBL440084', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845313, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895536, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '11.91', 'le': '0.24', 'lle': '1.36', 'sei': '6'}, 'molecule_chembl_id': 'CHEMBL1336', 'parent_molecule_chembl_id': 'CHEMBL1336', 'pchembl_value': '5.54', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '2900', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845314, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '2900', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895537, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '14.92', 'le': '0.27', 'lle': '3.14', 'sei': '10.02'}, 'molecule_chembl_id': 'CHEMBL388978', 'parent_molecule_chembl_id': 'CHEMBL388978', 'pchembl_value': '6.96', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '110', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845315, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '110', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895538, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1[nH]c(\\C=C\\2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NC[C@H](O)CN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1721885', 'parent_molecule_chembl_id': 'CHEMBL1721885', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845316, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895539, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCNC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccc(F)cc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '15.06', 'le': '0.28', 'lle': '3', 'sei': '7.77'}, 'molecule_chembl_id': 'CHEMBL535', 'parent_molecule_chembl_id': 'CHEMBL535', 'pchembl_value': '6', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845317, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895540, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(Sc4ccc(NC(=O)C5CC5)cc4)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '18.08', 'le': '0.35', 'lle': '3.95', 'sei': '6.59'}, 'molecule_chembl_id': 'CHEMBL572878', 'parent_molecule_chembl_id': 'CHEMBL572878', 'pchembl_value': '8.4', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '4', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845318, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895541, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(SC2=NN3C=NC(=O)C(=C3C=C2)c4c(Cl)cccc4Cl)c(F)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '13.11', 'le': '0.28', 'lle': '0.38', 'sei': '8.13'}, 'molecule_chembl_id': 'CHEMBL119385', 'parent_molecule_chembl_id': 'CHEMBL119385', 'pchembl_value': '5.72', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1900', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845319, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1900', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2895542, 'assay_chembl_id': 'CHEMBL1061131', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC4CCN(C)CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1150977', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2008, 'ligand_efficiency': {'bei': '15.07', 'le': '0.33', 'lle': '2.07', 'sei': '12.03'}, 'molecule_chembl_id': 'CHEMBL24828', 'parent_molecule_chembl_id': 'CHEMBL24828', 'pchembl_value': '7.16', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '69', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 845320, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 2921452, 'assay_chembl_id': 'CHEMBL1057559', 'assay_description': 'Inhibition of ABL2 assessed as enzyme activity at 1 uM relative to untreated control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cl.Cl.Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1Nc4ncccc4c5ncnc6[nH]cnc56', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1155237', 'document_journal': 'J. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3215582', 'parent_molecule_chembl_id': 'CHEMBL1197798', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 853311, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 2928459, 'assay_chembl_id': 'CHEMBL1049957', 'assay_description': 'Binding affinity to ABL2 assessed as percentage of kinase remaining bound to the bead at 1 uM by T7 phage display based binding assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccccc1n2c(cn3c4C(=O)NC(=O)N(C)c4nc23)c5cc(O)ccc5C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1154183', 'document_journal': 'J. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL566515', 'parent_molecule_chembl_id': 'CHEMBL566515', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '0.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 850094, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '0.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3052518, 'assay_chembl_id': 'CHEMBL1047769', 'assay_description': 'Residual activity of ABL2 at 1 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3F)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCN(C)CC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL604483', 'parent_molecule_chembl_id': 'CHEMBL604483', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 873100, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3052770, 'assay_chembl_id': 'CHEMBL1043849', 'assay_description': 'Residual activity of ABL2 at 10 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3F)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCN(C)CC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL604483', 'parent_molecule_chembl_id': 'CHEMBL604483', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 873100, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3054079, 'assay_chembl_id': 'CHEMBL1066597', 'assay_description': 'Residual activity of ABL2 at 0.1 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCN(C)CC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL595143', 'parent_molecule_chembl_id': 'CHEMBL595143', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '100', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 872953, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '100', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3055366, 'assay_chembl_id': 'CHEMBL1047769', 'assay_description': 'Residual activity of ABL2 at 1 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCN(C)CC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL595143', 'parent_molecule_chembl_id': 'CHEMBL595143', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 872953, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3055618, 'assay_chembl_id': 'CHEMBL1043849', 'assay_description': 'Residual activity of ABL2 at 10 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCN(C)CC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL595143', 'parent_molecule_chembl_id': 'CHEMBL595143', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '170', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 872953, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '170', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3056923, 'assay_chembl_id': 'CHEMBL1066597', 'assay_description': 'Residual activity of ABL2 at 0.1 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCCC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL595373', 'parent_molecule_chembl_id': 'CHEMBL595373', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '116', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 872954, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '116', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3058243, 'assay_chembl_id': 'CHEMBL1047769', 'assay_description': 'Residual activity of ABL2 at 1 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCCC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL595373', 'parent_molecule_chembl_id': 'CHEMBL595373', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 872954, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3058495, 'assay_chembl_id': 'CHEMBL1043849', 'assay_description': 'Residual activity of ABL2 at 10 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCCC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL595373', 'parent_molecule_chembl_id': 'CHEMBL595373', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '147', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 872954, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '147', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3072841, 'assay_chembl_id': 'CHEMBL1066597', 'assay_description': 'Residual activity of ABL2 at 0.1 uM by microplate scintillation counting', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(cc3F)c4nc5ccccc5s4)ncnc2cc1OCCCN6CCN(C)CC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1152560', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL604483', 'parent_molecule_chembl_id': 'CHEMBL604483', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual activity', 'published_units': '%', 'published_value': '96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 873100, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual activity', 'standard_units': '%', 'standard_value': '96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3213781, 'assay_chembl_id': 'CHEMBL1107585', 'assay_description': 'Inhibition of ARG at 5 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(=O)O.Clc1ccccc1NC(=O)c2cnc3ccc(cn23)C4CCNCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1154316', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1077739', 'parent_molecule_chembl_id': 'CHEMBL1198514', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '102', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 897686, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '102', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3224753, 'assay_chembl_id': 'CHEMBL1102590', 'assay_description': 'Inhibition of ABL2 at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=CC(=C(Br)C(=O)N1c2cnc(CO)cn2)OCc3ccc(F)cc3F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1154277', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1081678', 'parent_molecule_chembl_id': 'CHEMBL1081678', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 897055, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3224998, 'assay_chembl_id': 'CHEMBL1102590', 'assay_description': 'Inhibition of ABL2 at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)Cc1ccc(CN2C(=CC(=C(Br)C2=O)OCc3ccc(F)cc3F)C)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1154277', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1078665', 'parent_molecule_chembl_id': 'CHEMBL1078665', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 897300, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3331814, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc(cn2)c3cnc4NCCN(Cc5cc(F)ccc5F)c4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1165499', 'parent_molecule_chembl_id': 'CHEMBL1165499', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918577, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3333229, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc(cn2)c3cnc4NCCN(Cc5cc(Cl)ccc5C(F)(F)F)c4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1164180', 'parent_molecule_chembl_id': 'CHEMBL1164180', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918578, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3334634, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc(cn2)c3cnc4NCCN(Cc5cc(Cl)ccc5Cl)c4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1164181', 'parent_molecule_chembl_id': 'CHEMBL1164181', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918580, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3336054, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc(cn2)c3cnc4NCCN(Cc5c(F)ccc(F)c5Cl)c4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1164265', 'parent_molecule_chembl_id': 'CHEMBL1164265', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918645, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3337440, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1ccc(cc1)c2cnc3NCCN(Cc4cc(Cl)ccc4C(F)(F)F)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1163510', 'parent_molecule_chembl_id': 'CHEMBL1163510', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918712, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3337688, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1ccc(Cl)cc1CN2CCNc3ncc(cc23)c4ccc(cc4)C(=O)N5CCCCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1163518', 'parent_molecule_chembl_id': 'CHEMBL1163518', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918805, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3339019, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC1CCN(CC1)C(=O)c2ccc(cc2)c3cnc4NCCN(Cc5cc(Cl)ccc5C(F)(F)F)c4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1163567', 'parent_molecule_chembl_id': 'CHEMBL1163567', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918806, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3339275, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1ccc(Cl)cc1CN2CCNc3ncc(cc23)c4ccc(cc4)C(=O)N5CCC(CC5)N6CCCC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1163559', 'parent_molecule_chembl_id': 'CHEMBL1163559', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '75.9', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918807, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '75.9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3340582, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1ccc(Cl)cc1CN2CCNc3ncc(cc23)c4ccnc(c4)N5CCNCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1163566', 'parent_molecule_chembl_id': 'CHEMBL1163566', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918808, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3341998, 'assay_chembl_id': 'CHEMBL1168581', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)N1CCN(CC1)c2cc(ccn2)c3cnc4NCCN(Cc5cc(Cl)ccc5C(F)(F)F)c4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1165965', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1163565', 'parent_molecule_chembl_id': 'CHEMBL1163565', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 918809, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3358441, 'assay_chembl_id': 'CHEMBL1174055', 'assay_description': 'Inhibition of ABL2 at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc4cccnc4)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1177794', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1171523', 'parent_molecule_chembl_id': 'CHEMBL1171523', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '0.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 921401, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3358883, 'assay_chembl_id': 'CHEMBL1174055', 'assay_description': 'Inhibition of ABL2 at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc4cnc5[nH]ccc5c4)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1177794', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1170139', 'parent_molecule_chembl_id': 'CHEMBL1170139', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '0', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 921546, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3443332, 'assay_chembl_id': 'CHEMBL1243984', 'assay_description': 'Inhibition of ABL2 at 1 uM after 60 mins by FRET assay in presence of 10 uM ATP', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1nc(c2ccc(Br)c(O)c2)c3c(N)ncnc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240340', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1241578', 'parent_molecule_chembl_id': 'CHEMBL1241578', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 952381, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3443549, 'assay_chembl_id': 'CHEMBL1243984', 'assay_description': 'Inhibition of ABL2 at 1 uM after 60 mins by FRET assay in presence of 10 uM ATP', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2c1c(nn2C3CCCC3)c4cnc5[nH]ccc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240340', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1081312', 'parent_molecule_chembl_id': 'CHEMBL1081312', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 952382, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3444704, 'assay_chembl_id': 'CHEMBL1243984', 'assay_description': 'Inhibition of ABL2 at 1 uM after 60 mins by FRET assay in presence of 10 uM ATP', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1nc(c2ccc3ncccc3c2)c4c(N)ncnc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240340', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1233882', 'parent_molecule_chembl_id': 'CHEMBL1233882', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '70', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 952383, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '70', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3445328, 'assay_chembl_id': 'CHEMBL1243984', 'assay_description': 'Inhibition of ABL2 at 1 uM after 60 mins by FRET assay in presence of 10 uM ATP', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1OC)c2nn(C3CCC3)c4ncnc(N)c24', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240340', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1233881', 'parent_molecule_chembl_id': 'CHEMBL1233881', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 952519, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3445545, 'assay_chembl_id': 'CHEMBL1243984', 'assay_description': 'Inhibition of ABL2 at 1 uM after 60 mins by FRET assay in presence of 10 uM ATP', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1nc(c2cc3cc(O)ccc3[nH]2)c4c(N)ncnc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240340', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1241674', 'parent_molecule_chembl_id': 'CHEMBL1241674', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 952520, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3445763, 'assay_chembl_id': 'CHEMBL1243984', 'assay_description': 'Inhibition of ABL2 at 1 uM after 60 mins by FRET assay in presence of 10 uM ATP', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1nc(c2cccc(O)c2)c3c(N)ncnc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240340', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1230790', 'parent_molecule_chembl_id': 'CHEMBL1230790', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 951710, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3445953, 'assay_chembl_id': 'CHEMBL1243984', 'assay_description': 'Inhibition of ABL2 at 1 uM after 60 mins by FRET assay in presence of 10 uM ATP', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1nc(c2ccc3ccccc3c2)c4c(N)ncnc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240340', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2008, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1234815', 'parent_molecule_chembl_id': 'CHEMBL1234815', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 952659, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3446186, 'assay_chembl_id': 'CHEMBL1244324', 'assay_description': 'Inhibition of ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240341', 'document_journal': 'Leukemia', 'document_year': 2009, 'ligand_efficiency': {'bei': '17.53', 'le': '0.35', 'lle': '4.42', 'sei': '11.22'}, 'molecule_chembl_id': 'CHEMBL288441', 'parent_molecule_chembl_id': 'CHEMBL288441', 'pchembl_value': '9.3', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '0.5', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 952798, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '0.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 3448684, 'assay_chembl_id': 'CHEMBL1244711', 'assay_description': 'Binding affinity to ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35)N(C)C(=O)c9ccccc9', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240346', 'document_journal': 'Blood', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL608533', 'parent_molecule_chembl_id': 'CHEMBL608533', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 951114, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 3449390, 'assay_chembl_id': 'CHEMBL1244711', 'assay_description': 'Binding affinity to ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCNC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccc(F)cc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240346', 'document_journal': 'Blood', 'document_year': 2009, 'ligand_efficiency': {'bei': '15.06', 'le': '0.28', 'lle': '3', 'sei': '7.77'}, 'molecule_chembl_id': 'CHEMBL535', 'parent_molecule_chembl_id': 'CHEMBL535', 'pchembl_value': '6', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 952804, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 3449391, 'assay_chembl_id': 'CHEMBL1244711', 'assay_description': 'Binding affinity to ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240346', 'document_journal': 'Blood', 'document_year': 2009, 'ligand_efficiency': {'bei': '11.91', 'le': '0.24', 'lle': '1.36', 'sei': '6'}, 'molecule_chembl_id': 'CHEMBL1336', 'parent_molecule_chembl_id': 'CHEMBL1336', 'pchembl_value': '5.54', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '2900', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 952676, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '2900', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 3449547, 'assay_chembl_id': 'CHEMBL1244711', 'assay_description': 'Binding affinity to ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1onc(NC(=O)Nc2ccc(cc2)c3cn4c5ccc(OCCN6CCOCC6)cc5sc4n3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240346', 'document_journal': 'Blood', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL576982', 'parent_molecule_chembl_id': 'CHEMBL576982', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 952537, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 3449906, 'assay_chembl_id': 'CHEMBL1244711', 'assay_description': 'Binding affinity to ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@]12O[C@H](C[C@]1(O)CO)n3c4ccccc4c5c6C(=O)NCc6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240346', 'document_journal': 'Blood', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL603469', 'parent_molecule_chembl_id': 'CHEMBL603469', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 952538, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 3449973, 'assay_chembl_id': 'CHEMBL1244711', 'assay_description': 'Binding affinity to ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(ncnc2cc1OCCCN3CCCCC3)N4CCN(CC4)C(=O)Nc5ccc(OC(C)C)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240346', 'document_journal': 'Blood', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL124660', 'parent_molecule_chembl_id': 'CHEMBL124660', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 952675, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 3450901, 'assay_chembl_id': 'CHEMBL1244711', 'assay_description': 'Binding affinity to ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n3c4ccccc4c5c6[C@H](O)NC(=O)c6c7c8ccccc8n2c7c35)N(C)C(=O)c9ccccc9', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1240346', 'document_journal': 'Blood', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1240703', 'parent_molecule_chembl_id': 'CHEMBL1240703', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 951115, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 3463165, 'assay_chembl_id': 'CHEMBL1251625', 'assay_description': 'Inhibition of ABL2 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay relative to untreated control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1n[nH]c2ccc(cc12)c3cncc(OC[C@@H](N)Cc4c[nH]c5ccccc45)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1250448', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL379300', 'parent_molecule_chembl_id': 'CHEMBL379300', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '6', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 956180, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3463384, 'assay_chembl_id': 'CHEMBL1251625', 'assay_description': 'Inhibition of ABL2 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay relative to untreated control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccccc1N2CCN(CC2)c3ncnc4[nH]nc(Br)c34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1250448', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1254209', 'parent_molecule_chembl_id': 'CHEMBL1254209', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 956402, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3463928, 'assay_chembl_id': 'CHEMBL1251625', 'assay_description': 'Inhibition of ABL2 at 1 uM in presence of 10 uM ATP by Select Screen kinase assay relative to untreated control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Ic1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)c4cccs4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1250448', 'document_journal': 'Nat. Chem. Biol.', 'document_year': 2009, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL577784', 'parent_molecule_chembl_id': 'CHEMBL577784', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 956403, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 3590796, 'assay_chembl_id': 'CHEMBL1292129', 'assay_description': 'Inhibition of human ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000192', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(CNc2ccnc3oc4ccccc4c23)cc1', 'data_validity_comment': 'Values for this activity type are unusually large/small, so may not be accurate', 'document_chembl_id': 'CHEMBL1287713', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2010, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1290072', 'parent_molecule_chembl_id': 'CHEMBL1290072', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Ki', 'published_units': 'uM', 'published_value': '1000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 975530, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Ki', 'standard_units': 'nM', 'standard_value': '1000000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 5120413, 'assay_chembl_id': 'CHEMBL1648172', 'assay_description': 'Inhibition of human Arg at 10 uM after 60 mins by TR-FRET assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'S=C1NN=C(N1c2ccc3ccccc3c2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1641539', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1644616', 'parent_molecule_chembl_id': 'CHEMBL1644616', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '109', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1320437, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '109', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 6155508, 'assay_chembl_id': 'CHEMBL1764253', 'assay_description': 'Inhibition of Abl2 at 20 uM after 1 hr by luminescence assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(CN2CCN(CC2)C(=O)CN[C@H]3CCN(C3)S(=O)(=O)Cc4ccccc4)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1759999', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1760997', 'parent_molecule_chembl_id': 'CHEMBL1760997', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '4.49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1413134, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 6155509, 'assay_chembl_id': 'CHEMBL1764253', 'assay_description': 'Inhibition of Abl2 at 20 uM after 1 hr by luminescence assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(C)c(CN2CCN(CC2)C(=O)CN[C@H]3CCN(C3)S(=O)(=O)Cc4ccccc4)c(C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1759999', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1760998', 'parent_molecule_chembl_id': 'CHEMBL1760998', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '1.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1413135, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 6155510, 'assay_chembl_id': 'CHEMBL1764253', 'assay_description': 'Inhibition of Abl2 at 20 uM after 1 hr by luminescence assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(CN2CCN(CC2)C(=O)CN[C@H]3CCN(C3)S(=O)(=O)Cc4ccccc4)c(Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1759999', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1761145', 'parent_molecule_chembl_id': 'CHEMBL1761145', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '4.92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1413296, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 6155511, 'assay_chembl_id': 'CHEMBL1764253', 'assay_description': 'Inhibition of Abl2 at 20 uM after 1 hr by luminescence assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1759999', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL388978', 'parent_molecule_chembl_id': 'CHEMBL388978', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '90.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1413304, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '90.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 6167591, 'assay_chembl_id': 'CHEMBL1769234', 'assay_description': 'Binding affinity to human ABL2 phenylalanine residue assessed as residual binding at 1 uM by site dependent competitive binding assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccc(CNC(=O)CCl)cc2)cc1Nc3nccc(n3)c4cccnc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1764978', 'document_journal': 'J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1765717', 'parent_molecule_chembl_id': 'CHEMBL1765717', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1416412, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 6167615, 'assay_chembl_id': 'CHEMBL1768475', 'assay_description': 'Binding affinity to human ABL2 phenylalanine residue assessed as residual binding at 10 uM by site dependent competitive binding assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1764978', 'document_journal': 'J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL941', 'parent_molecule_chembl_id': 'CHEMBL941', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '0.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1416409, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '0.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 6174264, 'assay_chembl_id': 'CHEMBL1767522', 'assay_description': 'Binding affinity to human active site of N-terminal hexahistidine-tagged ABL2 expressed in Trichoplusia ni infected Sf9 cells by isothermal titration calorimetric assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000219', 'bao_label': 'cell-based format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1764982', 'document_journal': 'J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': {'bei': '16.66', 'le': '0.3', 'lle': '4', 'sei': '9.53'}, 'molecule_chembl_id': 'CHEMBL941', 'parent_molecule_chembl_id': 'CHEMBL941', 'pchembl_value': '8.22', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '6', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1418091, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '6', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 6174265, 'assay_chembl_id': 'CHEMBL1767523', 'assay_description': 'Binding affinity to human remote site of N-terminal hexahistidine-tagged ABL2 expressed in Trichoplusia ni infected Sf9 cells by isothermal titration calorimetric assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000219', 'bao_label': 'cell-based format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1764982', 'document_journal': 'J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': {'bei': '12.77', 'le': '0.23', 'lle': '2.08', 'sei': '7.3'}, 'molecule_chembl_id': 'CHEMBL941', 'parent_molecule_chembl_id': 'CHEMBL941', 'pchembl_value': '6.3', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'uM', 'published_value': '0.5', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1418091, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '500', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 6341010, 'assay_chembl_id': 'CHEMBL1827635', 'assay_description': 'Activity of ABL2 kinase at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)Nc1cn2nc(ccc2n1)c3cnc(Cl)c(NS(=O)(=O)c4ccc(F)cc4)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1821651', 'document_journal': 'J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1822054', 'parent_molecule_chembl_id': 'CHEMBL1822054', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '100', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1452528, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '100', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 7567391, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN5CCCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '13.62', 'le': '0.25', 'lle': '1.38', 'sei': '8.46'}, 'molecule_chembl_id': 'CHEMBL491473', 'parent_molecule_chembl_id': 'CHEMBL491473', 'pchembl_value': '6.14', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '730', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539344, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '730', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7567850, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H]1CCN(C[C@@H]1N(C)c2ncnc3[nH]ccc23)C(=O)CC#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL221959', 'parent_molecule_chembl_id': 'CHEMBL221959', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539358, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7567879, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\\C=C\\CN(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL180022', 'parent_molecule_chembl_id': 'CHEMBL180022', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539371, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7568347, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CSc1cccc(Nc2ncc3C=C(C(=O)N(C)c3n2)c4c(Cl)cccc4Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '20.66', 'le': '0.43', 'lle': '3.52', 'sei': '10.98'}, 'molecule_chembl_id': 'CHEMBL386051', 'parent_molecule_chembl_id': 'CHEMBL386051', 'pchembl_value': '9.16', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '0.69', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539385, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '0.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7568779, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1[nH]c(\\C=C\\2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NC[C@H](O)CN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1721885', 'parent_molecule_chembl_id': 'CHEMBL1721885', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539399, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7569364, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(cc12)C(=O)NOCCO', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1614701', 'parent_molecule_chembl_id': 'CHEMBL1614701', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539345, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7569854, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '16.21', 'le': '0.3', 'lle': '3.78', 'sei': '9.27'}, 'molecule_chembl_id': 'CHEMBL941', 'parent_molecule_chembl_id': 'CHEMBL941', 'pchembl_value': '8', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539372, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7570317, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1[nH]c(\\C=C\\2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc4c(Cl)cccc4Cl)c(C)c1C(=O)N5CCC[C@@H]5CN6CCCC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '8.04', 'le': '0.16', 'lle': '-0.53', 'sei': '4.65'}, 'molecule_chembl_id': 'CHEMBL450786', 'parent_molecule_chembl_id': 'CHEMBL450786', 'pchembl_value': '5.16', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '6900', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539386, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '6900', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7570744, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCNC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccc(F)cc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '15.06', 'le': '0.28', 'lle': '3', 'sei': '7.77'}, 'molecule_chembl_id': 'CHEMBL535', 'parent_molecule_chembl_id': 'CHEMBL535', 'pchembl_value': '6', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539400, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7571355, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(cnc1N)c2cnn(c2)C3CCNCC3)c4c(Cl)ccc(F)c4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '14.07', 'le': '0.29', 'lle': '2.65', 'sei': '8.13'}, 'molecule_chembl_id': 'CHEMBL601719', 'parent_molecule_chembl_id': 'CHEMBL601719', 'pchembl_value': '6.34', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '460', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539359, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '460', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7571831, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N#CC[C@H](C1CCCC1)n2cc(cn2)c3ncnc4[nH]ccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1789941', 'parent_molecule_chembl_id': 'CHEMBL1789941', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539373, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7572294, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cccc(c1)c2nc(N3CCOCC3)c4oc5ncccc5c4n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL573339', 'parent_molecule_chembl_id': 'CHEMBL573339', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539387, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7572710, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)N4CCC(CC4)N5CCN(C)CC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '10.45', 'le': '0.21', 'lle': '1.08', 'sei': '5.77'}, 'molecule_chembl_id': 'CHEMBL509032', 'parent_molecule_chembl_id': 'CHEMBL509032', 'pchembl_value': '6.42', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '380', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539401, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '380', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7572879, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC[C@H]1N(C2CCCC2)c3nc(Nc4ccc(cc4OC)C(=O)NC5CCN(C)CC5)ncc3N(C)C1=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL513909', 'parent_molecule_chembl_id': 'CHEMBL513909', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539346, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7573336, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1nc(Nc2ncc(s2)C(=O)Nc3c(C)cccc3Cl)cc(n1)N4CCN(CCO)CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '20.02', 'le': '0.4', 'lle': '6.33', 'sei': '7.25'}, 'molecule_chembl_id': 'CHEMBL1421', 'parent_molecule_chembl_id': 'CHEMBL1421', 'pchembl_value': '9.77', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '0.17', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539360, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '0.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7573812, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(C)CC(=O)N1CCC(CC1)c2ccc(NC(=O)c3nc(c[nH]3)C#N)c(c2)C4=CCCCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '11.45', 'le': '0.21', 'lle': '2.17', 'sei': '5.02'}, 'molecule_chembl_id': 'CHEMBL1908395', 'parent_molecule_chembl_id': 'CHEMBL1908842', 'pchembl_value': '5.28', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '5300', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539374, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '5300', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7574281, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35)N(C)C(=O)c9ccccc9', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL608533', 'parent_molecule_chembl_id': 'CHEMBL608533', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539388, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7574689, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(N)c2nc(c3cccc(O)c3)c(nc2n1)c4cccc(O)c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL230011', 'parent_molecule_chembl_id': 'CHEMBL230011', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539402, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7574857, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)c1ccc2\\C(=C(\\Nc3ccc(cc3)N(C)C(=O)CN4CCN(C)CC4)/c5ccccc5)\\C(=O)Nc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '10.56', 'le': '0.19', 'lle': '2.73', 'sei': '6.05'}, 'molecule_chembl_id': 'CHEMBL502835', 'parent_molecule_chembl_id': 'CHEMBL502835', 'pchembl_value': '5.7', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '2000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539347, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '2000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7575318, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '17.03', 'le': '0.32', 'lle': '2.39', 'sei': '8.96'}, 'molecule_chembl_id': 'CHEMBL553', 'parent_molecule_chembl_id': 'CHEMBL553', 'pchembl_value': '6.7', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '200', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539361, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '200', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7575789, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c4nccs4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '12.53', 'le': '0.24', 'lle': '2.66', 'sei': '4.56'}, 'molecule_chembl_id': 'CHEMBL1908396', 'parent_molecule_chembl_id': 'CHEMBL1908396', 'pchembl_value': '6.02', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '950', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539375, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '950', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7576254, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '13.46', 'le': '0.28', 'lle': '2.13', 'sei': '5.55'}, 'molecule_chembl_id': 'CHEMBL1230020', 'parent_molecule_chembl_id': 'CHEMBL1230020', 'pchembl_value': '5.57', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '2700', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539389, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '2700', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7576662, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc4cccc(c4)S(=O)(=O)NC(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '11.9', 'le': '0.23', 'lle': '1.12', 'sei': '5.34'}, 'molecule_chembl_id': 'CHEMBL1287853', 'parent_molecule_chembl_id': 'CHEMBL1287853', 'pchembl_value': '6.24', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '570', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539403, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '570', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7576831, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C\\C=C\\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]4CCOC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1173655', 'parent_molecule_chembl_id': 'CHEMBL1173655', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539348, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7577290, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc5ccc(F)cc5)cc3F)ccnc2cc1OCCCN6CCOCC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '11.96', 'le': '0.22', 'lle': '3.13', 'sei': '6.8'}, 'molecule_chembl_id': 'CHEMBL1230609', 'parent_molecule_chembl_id': 'CHEMBL1230609', 'pchembl_value': '7.57', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '27', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539362, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '27', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7577768, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(N1CCNCC1)c2ccc(\\C=C\\c3n[nH]c4ccccc34)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '19.86', 'le': '0.36', 'lle': '3.88', 'sei': '10.82'}, 'molecule_chembl_id': 'CHEMBL1908397', 'parent_molecule_chembl_id': 'CHEMBL1908397', 'pchembl_value': '6.6', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '250', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539376, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '250', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7578839, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1n[nH]c2ccc(cc12)c3cncc(OC[C@@H](N)Cc4ccccc4)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL379218', 'parent_molecule_chembl_id': 'CHEMBL379218', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539335, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7579213, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1)n2nc(cc2NC(=O)Nc3ccc(OCCN4CCOCC4)c5ccccc35)C(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '11.16', 'le': '0.21', 'lle': '-0.02', 'sei': '7.3'}, 'molecule_chembl_id': 'CHEMBL103667', 'parent_molecule_chembl_id': 'CHEMBL103667', 'pchembl_value': '5.89', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1300', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539349, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1300', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7579663, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CC[C@@H]([C@H](O)C1)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccccc4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL428690', 'parent_molecule_chembl_id': 'CHEMBL428690', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539363, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7580137, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL554', 'parent_molecule_chembl_id': 'CHEMBL554', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539377, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7580164, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1nc(c2cc3cc(O)ccc3[nH]2)c4c(N)ncnc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '19.2', 'le': '0.35', 'lle': '3.01', 'sei': '5.6'}, 'molecule_chembl_id': 'CHEMBL1241674', 'parent_molecule_chembl_id': 'CHEMBL1241674', 'pchembl_value': '5.92', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1200', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539390, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1200', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7580567, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC4CCN(C)CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '15.07', 'le': '0.33', 'lle': '2.07', 'sei': '12.03'}, 'molecule_chembl_id': 'CHEMBL24828', 'parent_molecule_chembl_id': 'CHEMBL24828', 'pchembl_value': '7.16', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '69', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539404, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7581197, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nc(cs4)c5cccnc5)c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '13.96', 'le': '0.26', 'lle': '2.48', 'sei': '6.85'}, 'molecule_chembl_id': 'CHEMBL1908391', 'parent_molecule_chembl_id': 'CHEMBL1908391', 'pchembl_value': '6.96', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '110', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539336, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '110', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7581582, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2nc(NCCN)c3ncc(C)n3c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL249697', 'parent_molecule_chembl_id': 'CHEMBL249697', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539350, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7582027, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCCn1cc(c2ccc3\\C(=N\\O)\\CCc3c2)c(n1)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL525191', 'parent_molecule_chembl_id': 'CHEMBL525191', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539364, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7582520, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(Nc2nnc(Cc3ccncc3)c4ccccc24)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL101253', 'parent_molecule_chembl_id': 'CHEMBL101253', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539391, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7582920, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(Sc4ccc(NC(=O)C5CC5)cc4)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '18.08', 'le': '0.35', 'lle': '3.95', 'sei': '6.59'}, 'molecule_chembl_id': 'CHEMBL572878', 'parent_molecule_chembl_id': 'CHEMBL572878', 'pchembl_value': '8.4', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '4', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539405, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7583543, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)c3cccc4[nH]nc(N)c34)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL223360', 'parent_molecule_chembl_id': 'CHEMBL223360', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539337, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7583940, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1oc(CSc2cnc(NC(=O)C3CCNCC3)s2)nc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL296468', 'parent_molecule_chembl_id': 'CHEMBL296468', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539351, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7584414, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cc(C2=C(C(=O)NC2=O)c3cn(C4CCN(Cc5ccccn5)CC4)c6ccccc36)c7ccccc17', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL300138', 'parent_molecule_chembl_id': 'CHEMBL300138', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539378, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7584876, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)Nc4n3)n2)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '13.06', 'le': '0.25', 'lle': '2.26', 'sei': '4.77'}, 'molecule_chembl_id': 'CHEMBL475251', 'parent_molecule_chembl_id': 'CHEMBL475251', 'pchembl_value': '6.14', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '720', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539392, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '720', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7585280, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(SC2=NN3C=NC(=O)C(=C3C=C2)c4c(Cl)cccc4Cl)c(F)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '13.11', 'le': '0.28', 'lle': '0.38', 'sei': '8.13'}, 'molecule_chembl_id': 'CHEMBL119385', 'parent_molecule_chembl_id': 'CHEMBL119385', 'pchembl_value': '5.72', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1900', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539406, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1900', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7585873, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1onc(NC(=O)Nc2ccc(cc2)c3cn4c5ccc(OCCN6CCOCC6)cc5sc4n3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL576982', 'parent_molecule_chembl_id': 'CHEMBL576982', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539338, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7586285, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CCOCC4)c3s2)c5cccc6[nH]ncc56)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL521851', 'parent_molecule_chembl_id': 'CHEMBL521851', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539365, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7586756, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c4cn(CCO1)c5ccccc45)c6ccccc26', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL91829', 'parent_molecule_chembl_id': 'CHEMBL91829', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539379, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7587210, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(F)c(F)c1C(=O)c2cnc(NC3CCN(CC3)S(=O)(=O)C)nc2N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL384304', 'parent_molecule_chembl_id': 'CHEMBL384304', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539393, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7587811, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '15.51', 'le': '0.29', 'lle': '2.26', 'sei': '6.78'}, 'molecule_chembl_id': 'CHEMBL377300', 'parent_molecule_chembl_id': 'CHEMBL377300', 'pchembl_value': '5.75', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1800', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539352, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1800', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7588264, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '12.97', 'le': '0.26', 'lle': '1.6', 'sei': '8.43'}, 'molecule_chembl_id': 'CHEMBL939', 'parent_molecule_chembl_id': 'CHEMBL939', 'pchembl_value': '5.8', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1600', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539366, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1600', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7588735, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1c(Cl)cc2c3ccncc3[nH]c2c1NC(=O)c4cccnc4C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL608154', 'parent_molecule_chembl_id': 'CHEMBL608154', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539380, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7589186, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[S+]([O-])c1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL10', 'parent_molecule_chembl_id': 'CHEMBL10', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539394, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7589357, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1ccccc1Sc2ccc3c(\\C=C\\c4ccccn4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '18.51', 'le': '0.35', 'lle': '2.66', 'sei': '7.46'}, 'molecule_chembl_id': 'CHEMBL1289926', 'parent_molecule_chembl_id': 'CHEMBL1289926', 'pchembl_value': '7.16', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '70', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539339, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '70', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7589781, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@]12O[C@H](C[C@]1(O)CO)n3c4ccccc4c5c6C(=O)NCc6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '11.8', 'le': '0.21', 'lle': '2.09', 'sei': '5.85'}, 'molecule_chembl_id': 'CHEMBL603469', 'parent_molecule_chembl_id': 'CHEMBL603469', 'pchembl_value': '5.19', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '6500', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539353, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '6500', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7590248, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1c(F)cccc1Nc2nc(Nc3cc4N(CCc4cc3OC)C(=O)CN(C)C)nc5[nH]ccc25', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL464552', 'parent_molecule_chembl_id': 'CHEMBL464552', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539367, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7590722, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(ncnc2cc1OCCCN3CCCCC3)N4CCN(CC4)C(=O)Nc5ccc(OC(C)C)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL124660', 'parent_molecule_chembl_id': 'CHEMBL124660', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539381, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7591173, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cc(cn1)c2ccc3nnc(Sc4ccc5ncccc5c4)n3n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1236107', 'parent_molecule_chembl_id': 'CHEMBL1236107', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539395, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7591330, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1(C)CNc2cc(NC(=O)c3cccnc3NCc4ccncc4)ccc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '14.32', 'le': '0.26', 'lle': '2.63', 'sei': '6.77'}, 'molecule_chembl_id': 'CHEMBL572881', 'parent_molecule_chembl_id': 'CHEMBL572881', 'pchembl_value': '5.35', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '4500', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539340, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '4500', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7591752, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc3nc([nH]c3c2)C4=C(N)c5c(F)cccc5NC4=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL522892', 'parent_molecule_chembl_id': 'CHEMBL522892', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539354, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7592224, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(CN4CCN(C)CC4)cc23)c5ccccc5C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1908394', 'parent_molecule_chembl_id': 'CHEMBL1908394', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539368, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7592697, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4c3n2)c5c(F)cccc5F)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '11.49', 'le': '0.22', 'lle': '-0.71', 'sei': '6.27'}, 'molecule_chembl_id': 'CHEMBL259084', 'parent_molecule_chembl_id': 'CHEMBL259084', 'pchembl_value': '5.48', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '3300', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539382, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '3300', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7593150, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '16.63', 'le': '0.33', 'lle': '3.94', 'sei': '10.65'}, 'molecule_chembl_id': 'CHEMBL288441', 'parent_molecule_chembl_id': 'CHEMBL288441', 'pchembl_value': '8.82', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1.5', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539396, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7593297, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '15.99', 'le': '0.3', 'lle': '3.96', 'sei': '8.95'}, 'molecule_chembl_id': 'CHEMBL574738', 'parent_molecule_chembl_id': 'CHEMBL574738', 'pchembl_value': '8.47', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '3.4', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539341, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '3.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7593732, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1c(Nc2ccc(cc2)C(F)(F)F)nc3cc(Oc4ccnc(c4)c5ncc([nH]5)C(F)(F)F)ccc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '11.04', 'le': '0.21', 'lle': '-0.75', 'sei': '7.09'}, 'molecule_chembl_id': 'CHEMBL558752', 'parent_molecule_chembl_id': 'CHEMBL558752', 'pchembl_value': '5.72', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '1900', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539355, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '1900', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7594204, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OC[C@H]3CCCNC3)c12)C#CC(C)(C)O)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL494089', 'parent_molecule_chembl_id': 'CHEMBL494089', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539369, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7594677, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cn(cn1)c2cc(NC(=O)c3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)cc(c2)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '14.32', 'le': '0.27', 'lle': '2.51', 'sei': '7.77'}, 'molecule_chembl_id': 'CHEMBL255863', 'parent_molecule_chembl_id': 'CHEMBL255863', 'pchembl_value': '7.59', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '26', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539383, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '26', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7595265, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1cccc(Cl)c1C(=O)Nc2c[nH]nc2C(=O)NC3CCNCC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL445813', 'parent_molecule_chembl_id': 'CHEMBL445813', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539342, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7595709, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '12.47', 'le': '0.24', 'lle': '2.02', 'sei': '6.84'}, 'molecule_chembl_id': 'CHEMBL31965', 'parent_molecule_chembl_id': 'CHEMBL31965', 'pchembl_value': '6.06', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '870', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539356, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '870', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7596183, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261849', 'parent_molecule_chembl_id': 'CHEMBL261849', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539370, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7596659, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '11.91', 'le': '0.24', 'lle': '1.36', 'sei': '6'}, 'molecule_chembl_id': 'CHEMBL1336', 'parent_molecule_chembl_id': 'CHEMBL1336', 'pchembl_value': '5.54', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '2900', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539397, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '2900', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7597237, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL215152', 'parent_molecule_chembl_id': 'CHEMBL215152', 'pchembl_value': None, 'potential_duplicate': True, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539343, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7597690, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(C(=O)NOCC2CC2)c(Nc3ccc(I)cc3Cl)c1F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL105442', 'parent_molecule_chembl_id': 'CHEMBL105442', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539357, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7598191, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(c1ccc2c(C)n(C)nc2c1)c3ccnc(Nc4ccc(C)c(c4)S(=O)(=O)N)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '12.62', 'le': '0.24', 'lle': '1.78', 'sei': '4.34'}, 'molecule_chembl_id': 'CHEMBL477772', 'parent_molecule_chembl_id': 'CHEMBL477772', 'pchembl_value': '5.52', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '3000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539384, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '3000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7598633, 'assay_chembl_id': 'CHEMBL1908690', 'assay_description': 'Binding constant for ABL2 kinase domain', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000034', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1908390', 'document_journal': 'Nat. Biotechnol.', 'document_year': 2011, 'ligand_efficiency': {'bei': '14.92', 'le': '0.27', 'lle': '3.14', 'sei': '10.02'}, 'molecule_chembl_id': 'CHEMBL388978', 'parent_molecule_chembl_id': 'CHEMBL388978', 'pchembl_value': '6.96', 'potential_duplicate': True, 'published_relation': '=', 'published_type': 'Kd', 'published_units': 'nM', 'published_value': '110', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1539398, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Kd', 'standard_units': 'nM', 'standard_value': '110', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7931065, 'assay_chembl_id': 'CHEMBL1919071', 'assay_description': 'Inhibition of ABL2 relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C\\C=C\\C(=O)N(C)c1cc2c(cc1F)nc(Nc3ccccc3C)c4cncn24', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1914368', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1916891', 'parent_molecule_chembl_id': 'CHEMBL1916891', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '65', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1559392, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '65', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 7959661, 'assay_chembl_id': 'CHEMBL1932271', 'assay_description': 'Inhibition of ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCN1CCN(CCC1=O)C(=O)c2cc(sc2NC(=O)Nc3cccc(Cl)c3Cl)C(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1926590', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1929238', 'parent_molecule_chembl_id': 'CHEMBL1929238', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '30', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1566418, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '30000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7959662, 'assay_chembl_id': 'CHEMBL1932271', 'assay_description': 'Inhibition of ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1)n2nc(cc2NC(=O)Nc3ccc(OCCN4CCOCC4)c5ccccc35)C(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1926590', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103667', 'parent_molecule_chembl_id': 'CHEMBL103667', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '30', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1566420, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '30000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 7996672, 'assay_chembl_id': 'CHEMBL1944003', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cccc(F)c1Nc2nc(Nc3ccc4c(NC(=O)[C@@H](CC4(C)C)NC(=O)N5CCCC5)c3)ncc2Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1938300', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1939491', 'parent_molecule_chembl_id': 'CHEMBL1939491', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1571363, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8046136, 'assay_chembl_id': 'CHEMBL1958809', 'assay_description': 'Inhibition of ABL2 at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc(Nc3nc(N)c(s3)C(=O)c4ccc5OCCOc5c4)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1955770', 'document_journal': 'J. Biol. Chem.', 'document_year': 2006, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1956070', 'parent_molecule_chembl_id': 'CHEMBL1956070', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1580282, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8061355, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NCc1ccc(cc1)c2nc(c3ccc(Cl)c(O)c3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909412', 'parent_molecule_chembl_id': 'CHEMBL200320', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583323, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8061532, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(C=NNc2ncnc3c2cnn3Cc4ccccc4)ccc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1789962', 'parent_molecule_chembl_id': 'CHEMBL1789962', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '49.24', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583532, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '49.24', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8061863, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)n2cnc(c3ccc(F)cc3)c2c4ccnc(Nc5ccccc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL318892', 'parent_molecule_chembl_id': 'CHEMBL318892', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.24', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583290, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.24', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8062054, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cc(C=C2C(=O)Nc3cccnc23)c4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1516890', 'parent_molecule_chembl_id': 'CHEMBL1516890', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583471, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8062394, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1c(nc2cnccc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188048', 'parent_molecule_chembl_id': 'CHEMBL188048', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583343, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8062556, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)C(=O)Nc2n[nH]c3nc(c(Br)cc23)c4ccc(O)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261129', 'parent_molecule_chembl_id': 'CHEMBL261129', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583337, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8062878, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2ccncc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185710', 'parent_molecule_chembl_id': 'CHEMBL185710', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583347, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8063234, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NCc1ccc(cc1)c2nc(c3ccc(Cl)c(O)c3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909412', 'parent_molecule_chembl_id': 'CHEMBL200320', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '55.78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583323, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '55.78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8063401, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc(Cl)c(c5)C(F)(F)F)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188794', 'parent_molecule_chembl_id': 'CHEMBL188794', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583627, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8063733, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NC(=O)c1ccc(cc1)c2nc(c3ccccn3)c([nH]2)c4ccc5OCOc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909378', 'parent_molecule_chembl_id': 'CHEMBL440084', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583321, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8063915, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cc(C=C2C(=O)Nc3cccnc23)c4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1516890', 'parent_molecule_chembl_id': 'CHEMBL1516890', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '20.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583471, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '20.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8064254, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1c(nc2cnccc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188048', 'parent_molecule_chembl_id': 'CHEMBL188048', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583343, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8064464, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C(=O)O[C@@H]1CN[C@H](C1)C#Cc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL466412', 'parent_molecule_chembl_id': 'CHEMBL466412', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583395, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8064826, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1ccc(Nc2oc(cn2)c3ccccc3)cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794060', 'parent_molecule_chembl_id': 'CHEMBL360561', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.21', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583499, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.21', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8064992, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc(Cl)c(c5)C(F)(F)F)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188794', 'parent_molecule_chembl_id': 'CHEMBL188794', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583627, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8065332, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NC(=O)c1ccc(cc1)c2nc(c3ccccn3)c([nH]2)c4ccc5OCOc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909378', 'parent_molecule_chembl_id': 'CHEMBL440084', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.03', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583321, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.03', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8065507, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(c1)c2nn3ncccc3c2c4ccnc(Nc5ccc6OCCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL362155', 'parent_molecule_chembl_id': 'CHEMBL362155', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.21', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583620, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.21', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8065731, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(c1)c2nn3ncccc3c2c4ccnc(Nc5ccc6OCCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL362155', 'parent_molecule_chembl_id': 'CHEMBL362155', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '32.13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583620, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '32.13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8065846, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2cnc(Oc3cccc(NC(=O)c4ccc(cc4)N(C)C)c3)cc12)c5nonc5N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL220465', 'parent_molecule_chembl_id': 'CHEMBL220465', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.48', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583397, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.48', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8066056, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C(=O)O[C@@H]1CN[C@H](C1)C#Cc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL466412', 'parent_molecule_chembl_id': 'CHEMBL466412', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583395, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8066280, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1nccc2c1nc(c3nonc3N)n2CC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365072', 'parent_molecule_chembl_id': 'CHEMBL365072', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583356, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8066416, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1ccc(Nc2oc(cn2)c3ccccc3)cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794060', 'parent_molecule_chembl_id': 'CHEMBL360561', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '57.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583499, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '57.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8066582, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2ccc3c(NC(=O)C4CC4)n[nH]c3n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL408732', 'parent_molecule_chembl_id': 'CHEMBL408732', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.81', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583335, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.81', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8066806, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2ccc3c(NC(=O)C4CC4)n[nH]c3n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL408732', 'parent_molecule_chembl_id': 'CHEMBL408732', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583335, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8066930, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)cc3)ccc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909370', 'parent_molecule_chembl_id': 'CHEMBL243908', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '16.06', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583553, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '16.06', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8067329, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909367', 'parent_molecule_chembl_id': 'CHEMBL244099', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583542, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8067450, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2cnc(Oc3cccc(NC(=O)c4ccc(cc4)N(C)C)c3)cc12)c5nonc5N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL220465', 'parent_molecule_chembl_id': 'CHEMBL220465', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583397, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8067674, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2nn3ccccc3c2c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL485745', 'parent_molecule_chembl_id': 'CHEMBL485745', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583467, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8067884, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1nccc2c1nc(c3nonc3N)n2CC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365072', 'parent_molecule_chembl_id': 'CHEMBL365072', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.26', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583356, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.26', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8068019, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2nccc(n2)c3cnn4ncccc34)cc(OC)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL359999', 'parent_molecule_chembl_id': 'CHEMBL359999', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583597, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8068407, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.N#Cc1cccc(Nc2oc(cn2)c3ccccc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794061', 'parent_molecule_chembl_id': 'CHEMBL192413', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583524, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8068532, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)cc3)ccc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909370', 'parent_molecule_chembl_id': 'CHEMBL243908', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '34.36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583553, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '34.36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8068756, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL397570', 'parent_molecule_chembl_id': 'CHEMBL397570', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.54', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583310, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.54', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8068930, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909367', 'parent_molecule_chembl_id': 'CHEMBL244099', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.34', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583542, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.34', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8069279, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2nn3ccccc3c2c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL485745', 'parent_molecule_chembl_id': 'CHEMBL485745', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583467, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8069350, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2nccc(n2)c3cnn4ncccc34)cc(OC)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL359999', 'parent_molecule_chembl_id': 'CHEMBL359999', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '69.6', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583597, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '69.6', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8069574, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc(Nc3nccc(n3)c4cnn5ncccc45)cc2C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL468963', 'parent_molecule_chembl_id': 'CHEMBL468963', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583576, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8069735, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.N#Cc1cccc(Nc2oc(cn2)c3ccccc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794061', 'parent_molecule_chembl_id': 'CHEMBL192413', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '20.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583524, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '20.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8070085, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL397570', 'parent_molecule_chembl_id': 'CHEMBL397570', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583310, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8070257, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2cc(ccc2c1)c3c(nc(c4ccc(cc4)[S+](C)[O-])n3C)c5ccncc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL399410', 'parent_molecule_chembl_id': 'CHEMBL399410', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.63', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583322, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.63', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8070606, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)c1ccc(cc1)c2cc(ccn2)c3c[nH]nc3c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL206544', 'parent_molecule_chembl_id': 'CHEMBL206544', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583544, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8070904, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2ccc(Nc3nccc(n3)c4cnn5ncccc45)cc2C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL468963', 'parent_molecule_chembl_id': 'CHEMBL468963', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '57.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583576, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '57.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8071061, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(Cl)cc2C(=NNc3ccc(cc3)S(=O)(=O)N)C(=O)Nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909397', 'parent_molecule_chembl_id': 'CHEMBL1909397', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583436, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8071411, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc(n1)c2n[nH]cc2c3ccc4ncccc4n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185238', 'parent_molecule_chembl_id': 'CHEMBL185238', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583589, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8071584, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2cc(ccc2c1)c3c(nc(c4ccc(cc4)[S+](C)[O-])n3C)c5ccncc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL399410', 'parent_molecule_chembl_id': 'CHEMBL399410', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583322, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8071808, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1cc2c(NC(=O)C3CC3)n[nH]c2nc1c4occc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL408564', 'parent_molecule_chembl_id': 'CHEMBL408564', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583349, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8071933, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)c1ccc(cc1)c2cc(ccn2)c3c[nH]nc3c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL206544', 'parent_molecule_chembl_id': 'CHEMBL206544', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '16.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583544, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '16.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8072247, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2cc(Oc3cccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)c3)ccc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909366', 'parent_molecule_chembl_id': 'CHEMBL244289', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583536, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8072404, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(Cl)cc2C(=NNc3ccc(cc3)S(=O)(=O)N)C(=O)Nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909397', 'parent_molecule_chembl_id': 'CHEMBL1909397', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583436, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8072628, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4ccccc4)cc3)ccc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909371', 'parent_molecule_chembl_id': 'CHEMBL243891', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583554, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8072753, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc(n1)c2n[nH]cc2c3ccc4ncccc4n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185238', 'parent_molecule_chembl_id': 'CHEMBL185238', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583589, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8073144, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1cc2c(NC(=O)C3CC3)n[nH]c2nc1c4occc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL408564', 'parent_molecule_chembl_id': 'CHEMBL408564', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '18.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583349, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '18.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8073269, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)cc2s1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909369', 'parent_molecule_chembl_id': 'CHEMBL244482', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '51.42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583552, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '51.42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8073612, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2NC(=O)\\C(=N/Nc3ccc(cc3)S(=O)(=O)N)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL271843', 'parent_molecule_chembl_id': 'CHEMBL271843', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.63', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583433, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.63', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8073845, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2cc(Oc3cccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)c3)ccc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909366', 'parent_molecule_chembl_id': 'CHEMBL244289', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '41.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583536, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '41.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8074221, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4ccccc4)cc3)ccc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909371', 'parent_molecule_chembl_id': 'CHEMBL243891', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '16.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583554, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '16.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8074351, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(=O)N(C)C)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL482326', 'parent_molecule_chembl_id': 'CHEMBL482326', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583373, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8074575, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(=O)N(C)C)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL482326', 'parent_molecule_chembl_id': 'CHEMBL482326', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583373, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8074732, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)Cc1ccccc1Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1785002', 'parent_molecule_chembl_id': 'CHEMBL1785002', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.21', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583303, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.21', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8074859, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)cc2s1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909369', 'parent_molecule_chembl_id': 'CHEMBL244482', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '73.6', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583552, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '73.6', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8075083, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2nc(Nc3cccc4ncccc34)c5cc[nH]c5n2)N6CCN(CC6)C(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL458438', 'parent_molecule_chembl_id': 'CHEMBL458438', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583378, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8075194, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2NC(=O)\\C(=N/Nc3ccc(cc3)S(=O)(=O)N)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL271843', 'parent_molecule_chembl_id': 'CHEMBL271843', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583433, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8075431, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nc(CN3CCCC3)cc12)C#CC(C)(C)O)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1096290', 'parent_molecule_chembl_id': 'CHEMBL1096290', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583367, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8075655, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nc(CN3CCCC3)cc12)C#CC(C)(C)O)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1096290', 'parent_molecule_chembl_id': 'CHEMBL1096290', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.65', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583367, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.65', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8075796, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1cc(NC2=C(C(=O)NC2=O)c3cccc(Cl)c3)ccc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL156987', 'parent_molecule_chembl_id': 'CHEMBL156987', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583318, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8076162, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2ncn(c3cc(O[C@H](C)c4ccccc4C(F)(F)F)c(s3)C(=O)N)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL522709', 'parent_molecule_chembl_id': 'CHEMBL522709', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583405, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8076310, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)Cc1ccccc1Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1785002', 'parent_molecule_chembl_id': 'CHEMBL1785002', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583303, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8076668, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2nc(Nc3cccc4ncccc34)c5cc[nH]c5n2)N6CCN(CC6)C(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL458438', 'parent_molecule_chembl_id': 'CHEMBL458438', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583378, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8076770, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(CCCN3CCOCC3)c2c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL14112', 'parent_molecule_chembl_id': 'CHEMBL14112', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583282, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8076994, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(CCCN3CCOCC3)c2c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL14112', 'parent_molecule_chembl_id': 'CHEMBL14112', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583282, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8077241, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nc(O[C@@H](CN)c3ccccc3)cc12)C#CC(C)(C)O)c4nonc4N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909349', 'parent_molecule_chembl_id': 'CHEMBL1099276', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583368, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8077369, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1cc(NC2=C(C(=O)NC2=O)c3cccc(Cl)c3)ccc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL156987', 'parent_molecule_chembl_id': 'CHEMBL156987', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583318, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8077744, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2ncn(c3cc(O[C@H](C)c4ccccc4C(F)(F)F)c(s3)C(=O)N)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL522709', 'parent_molecule_chembl_id': 'CHEMBL522709', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583405, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8077887, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCCc4ccccc4)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL473629', 'parent_molecule_chembl_id': 'CHEMBL473629', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.26', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583386, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.26', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8078250, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(Nc2cc(n[nH]2)c3ccc(O)c(F)c3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103115', 'parent_molecule_chembl_id': 'CHEMBL103115', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583268, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8078576, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.ON=C1CCc2cc(ccc12)c3nc([nH]c3c4ccncc4)C5CCNCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794071', 'parent_molecule_chembl_id': 'CHEMBL1851806', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583326, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8078826, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nc(O[C@@H](CN)c3ccccc3)cc12)C#CC(C)(C)O)c4nonc4N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909349', 'parent_molecule_chembl_id': 'CHEMBL1099276', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583368, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8078942, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1oc(nn1)c2ccc(C)c(c2)c3ccc(cc3)C(=O)Nc4cccc(c4)C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL270164', 'parent_molecule_chembl_id': 'CHEMBL270164', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583513, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8079166, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1oc(nn1)c2ccc(C)c(c2)c3ccc(cc3)C(=O)Nc4cccc(c4)C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL270164', 'parent_molecule_chembl_id': 'CHEMBL270164', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583513, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8079324, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(OC[C@@H](O)CO)cc23)c4ccccc4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794067', 'parent_molecule_chembl_id': 'CHEMBL1794067', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583429, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8079466, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCCc4ccccc4)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL473629', 'parent_molecule_chembl_id': 'CHEMBL473629', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.26', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583386, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.26', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8079690, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.[O-][S+]1CCN(Cc2oc(cc2)c3ccc4ncnc(Nc5ccc(OCc6ccccc6)c(F)c5)c4c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909391', 'parent_molecule_chembl_id': 'CHEMBL215716', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.02', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583503, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.02', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8079829, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(Nc2cc(n[nH]2)c3ccc(O)c(F)c3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103115', 'parent_molecule_chembl_id': 'CHEMBL103115', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '16.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583268, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '16.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8080158, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.ON=C1CCc2cc(ccc12)c3nc([nH]c3c4ccncc4)C5CCNCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794071', 'parent_molecule_chembl_id': 'CHEMBL1851806', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583326, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8080410, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)COC(=O)c1ccc2NC(=O)\\C(=C/Nc3ccc(cc3)S(=O)(=O)N)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL269883', 'parent_molecule_chembl_id': 'CHEMBL269883', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583463, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8080749, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909411', 'parent_molecule_chembl_id': 'CHEMBL15202', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583364, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8080913, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(OC[C@@H](O)CO)cc23)c4ccccc4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794067', 'parent_molecule_chembl_id': 'CHEMBL1794067', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583429, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8081272, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.[O-][S+]1CCN(Cc2oc(cc2)c3ccc4ncnc(Nc5ccc(OCc6ccccc6)c(F)c5)c4c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909391', 'parent_molecule_chembl_id': 'CHEMBL215716', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583503, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8081416, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCN1CCC(CC1)c2ccc(Nc3nc(Nc4cc(F)ccc4C(=O)N)c5cc[nH]c5n3)c(OC)c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL476259', 'parent_molecule_chembl_id': 'CHEMBL476259', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583376, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8081743, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(NC2=C(C(=O)NC2=O)c3cccc(Cl)c3)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL160333', 'parent_molecule_chembl_id': 'CHEMBL160333', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583319, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8081995, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)COC(=O)c1ccc2NC(=O)\\C(=C/Nc3ccc(cc3)S(=O)(=O)N)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL269883', 'parent_molecule_chembl_id': 'CHEMBL269883', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '20.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583463, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '20.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8082332, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909411', 'parent_molecule_chembl_id': 'CHEMBL15202', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.53', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583364, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.53', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8082505, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Nc1nccc(n1)c2c(ncn2C3CCNCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909407', 'parent_molecule_chembl_id': 'CHEMBL274064', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.01', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583285, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.01', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8082852, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1c2ccc(cc2)C(=O)NCC3CC3)C(=O)NC4CCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517507', 'parent_molecule_chembl_id': 'CHEMBL517507', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583582, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8083008, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCN1CCC(CC1)c2ccc(Nc3nc(Nc4cc(F)ccc4C(=O)N)c5cc[nH]c5n3)c(OC)c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL476259', 'parent_molecule_chembl_id': 'CHEMBL476259', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.54', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583376, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.54', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8083232, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(cc23)C(=O)NCCCn4ccnc4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272026', 'parent_molecule_chembl_id': 'CHEMBL272026', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583443, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8083331, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(NC2=C(C(=O)NC2=O)c3cccc(Cl)c3)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL160333', 'parent_molecule_chembl_id': 'CHEMBL160333', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583319, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8083585, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nonc1c2nc3cnccc3n2C4CCCCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189231', 'parent_molecule_chembl_id': 'CHEMBL189231', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583340, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8083809, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nonc1c2nc3cnccc3n2C4CCCCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189231', 'parent_molecule_chembl_id': 'CHEMBL189231', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583340, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8083919, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)n2cnc(c3ccc(F)cc3)c2c4ccnc(N)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL95207', 'parent_molecule_chembl_id': 'CHEMBL95207', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583286, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8084104, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Nc1nccc(n1)c2c(ncn2C3CCNCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909407', 'parent_molecule_chembl_id': 'CHEMBL274064', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583285, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8084328, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc4ncccc4c23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL409892', 'parent_molecule_chembl_id': 'CHEMBL409892', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583453, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8084446, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1c2ccc(cc2)C(=O)NCC3CC3)C(=O)NC4CCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517507', 'parent_molecule_chembl_id': 'CHEMBL517507', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.48', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583582, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.48', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8084831, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(cc23)C(=O)NCCCn4ccnc4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272026', 'parent_molecule_chembl_id': 'CHEMBL272026', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583443, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8084929, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)Nc1cccc(c1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103080', 'parent_molecule_chembl_id': 'CHEMBL103080', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583351, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8085153, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)Nc1cccc(c1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103080', 'parent_molecule_chembl_id': 'CHEMBL103080', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583351, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8085409, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(C=NNc2ncnc3c2cnn3Cc4ccccc4)ccc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1789962', 'parent_molecule_chembl_id': 'CHEMBL1789962', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '20.33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583532, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '20.33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8085517, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)n2cnc(c3ccc(F)cc3)c2c4ccnc(N)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL95207', 'parent_molecule_chembl_id': 'CHEMBL95207', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583286, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8085741, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)n2cnc(c3ccc(F)cc3)c2c4ccnc(Nc5ccccc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL318892', 'parent_molecule_chembl_id': 'CHEMBL318892', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583290, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8085930, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc4ncccc4c23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL409892', 'parent_molecule_chembl_id': 'CHEMBL409892', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '33.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583453, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '33.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8086045, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1cc2c(Nc3ccc4c(cnn4Cc5ccccc5)c3)ncnc2cn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL30432', 'parent_molecule_chembl_id': 'CHEMBL30432', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.06', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583440, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.06', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8086269, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1cc2c(Nc3ccc4c(cnn4Cc5ccccc5)c3)ncnc2cn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL30432', 'parent_molecule_chembl_id': 'CHEMBL30432', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.48', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583440, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.48', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8086431, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)C(=O)Nc2n[nH]c3nc(c(Br)cc23)c4ccc(O)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261129', 'parent_molecule_chembl_id': 'CHEMBL261129', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583337, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8086754, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2ccncc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185710', 'parent_molecule_chembl_id': 'CHEMBL185710', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583347, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8086965, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cncc(\\C=C\\c2c(Cl)cccc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL263796', 'parent_molecule_chembl_id': 'CHEMBL263796', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583475, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8087347, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCC(=O)Nc1ccc(C)c(c1)c2ccc(cc2)C(=O)NCC3CC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517666', 'parent_molecule_chembl_id': 'CHEMBL517666', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583595, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8087461, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCS(=O)(=O)c1ccc(OC)c(Nc2nccc(n2)N(C)c3ccc4c(C)n[nH]c4c3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909358', 'parent_molecule_chembl_id': 'CHEMBL475932', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '73.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583535, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '73.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8087823, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2oc(cc2)c3cc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4s3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL475761', 'parent_molecule_chembl_id': 'CHEMBL475761', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583584, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8087965, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCn1c(nc2cncc(C(=O)N3CCNCC3)c12)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909376', 'parent_molecule_chembl_id': 'CHEMBL493066', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.81', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583358, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.81', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8088189, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCn1c(nc2cncc(C(=O)N3CCNCC3)c12)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909376', 'parent_molecule_chembl_id': 'CHEMBL493066', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583358, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8088337, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)Nc1ccc(cc1)c2cc(cc(C(=O)N)c2N)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL230597', 'parent_molecule_chembl_id': 'CHEMBL230597', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583415, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8088689, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(O[C@@H](C)c4ccccc4Cl)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL521806', 'parent_molecule_chembl_id': 'CHEMBL521806', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.24', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583393, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.24', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8088782, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2ccccc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365286', 'parent_molecule_chembl_id': 'CHEMBL365286', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.04', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583484, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.04', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8089006, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2ccccc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365286', 'parent_molecule_chembl_id': 'CHEMBL365286', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583484, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8089134, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCN1CCC(CC1)Oc2cc(Nc3nc(Nc4cccc(F)c4C(=O)N)c5cc[nH]c5n3)c(OC)cc2Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517171', 'parent_molecule_chembl_id': 'CHEMBL517171', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583379, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8089506, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=Cc1cccc2NC(=O)\\C(=N/Nc3ccc(cc3)S(=O)(=O)N)\\c12)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL270544', 'parent_molecule_chembl_id': 'CHEMBL270544', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.09', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583456, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.09', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8089626, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccnc(c2)N3CCOCC3)cc1c4ccc(cc4)C(=O)NCC5CC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL476351', 'parent_molecule_chembl_id': 'CHEMBL476351', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '19.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583574, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '19.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8089850, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3ccccc3Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL179453', 'parent_molecule_chembl_id': 'CHEMBL179453', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583522, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8090030, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)c2c(nn3cc(ccc23)C(F)(F)F)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909402', 'parent_molecule_chembl_id': 'CHEMBL1909402', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583490, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8090195, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2CCN(C(=O)CN3CCN(CC3)C(C)C)c2cc1Nc4nc(Nc5cccc(F)c5C(=O)N)c6cc[nH]c6n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL505915', 'parent_molecule_chembl_id': 'CHEMBL505915', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.03', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583380, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.03', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8090586, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1nc(c2ccccc2)n3nc(NCCCN4CCOCC4)ncc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL486124', 'parent_molecule_chembl_id': 'CHEMBL486124', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583280, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8090725, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1ccc2c(cnn2n1)c3ccnc(Nc4cccc(c4)C(F)(F)F)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL183993', 'parent_molecule_chembl_id': 'CHEMBL183993', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583610, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8090949, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1)c3ccnc(Nc4cccc(c4)S(=O)(=O)N)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188381', 'parent_molecule_chembl_id': 'CHEMBL188381', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '20.18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583601, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '20.18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8091154, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909385', 'parent_molecule_chembl_id': 'CHEMBL213342', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583480, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8091291, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cncc(\\C=C\\c2c(Cl)cccc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL263796', 'parent_molecule_chembl_id': 'CHEMBL263796', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '35.68', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583475, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '35.68', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8091670, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCC(=O)Nc1ccc(C)c(c1)c2ccc(cc2)C(=O)NCC3CC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517666', 'parent_molecule_chembl_id': 'CHEMBL517666', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583595, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8091786, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1ccccc1Nc2oc(cn2)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794062', 'parent_molecule_chembl_id': 'CHEMBL194027', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583504, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8092010, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1ccccc1Nc2oc(cn2)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794062', 'parent_molecule_chembl_id': 'CHEMBL194027', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583504, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8092147, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccccc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275798', 'parent_molecule_chembl_id': 'CHEMBL275798', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583291, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8092522, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCc1cc(cs1)c2cc3c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)ncnc3s2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL475599', 'parent_molecule_chembl_id': 'CHEMBL475599', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583402, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8092670, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)Nc1ccc(cc1)c2cc(cc(C(=O)N)c2N)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL230597', 'parent_molecule_chembl_id': 'CHEMBL230597', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583415, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8093023, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(O[C@@H](C)c4ccccc4Cl)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL521806', 'parent_molecule_chembl_id': 'CHEMBL521806', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583393, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8093335, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCCCNc1nccc(n1)c2c(nn3cc(ccc23)C(F)(F)F)c4ccc(F)cc4.OC(=O)\\C=C\\C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909403', 'parent_molecule_chembl_id': 'CHEMBL1952232', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.63', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583492, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.63', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8093475, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCN1CCC(CC1)Oc2cc(Nc3nc(Nc4cccc(F)c4C(=O)N)c5cc[nH]c5n3)c(OC)cc2Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517171', 'parent_molecule_chembl_id': 'CHEMBL517171', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.32', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583379, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.32', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8093838, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=Cc1cccc2NC(=O)\\C(=N/Nc3ccc(cc3)S(=O)(=O)N)\\c12)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL270544', 'parent_molecule_chembl_id': 'CHEMBL270544', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '14', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583456, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8094182, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3ccccc3Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL179453', 'parent_molecule_chembl_id': 'CHEMBL179453', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '24.51', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583522, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '24.51', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8094362, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1cc(cc(C)c1\\C=C\\c2cncc(c2)c3nn[nH]n3)c4occc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909353', 'parent_molecule_chembl_id': 'CHEMBL373576', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583479, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8094537, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2CCN(C(=O)CN3CCN(CC3)C(C)C)c2cc1Nc4nc(Nc5cccc(F)c5C(=O)N)c6cc[nH]c6n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL505915', 'parent_molecule_chembl_id': 'CHEMBL505915', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583380, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8094761, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2nc(Nc3ccc(F)cc3C(=O)N)c4cc[nH]c4n2)N5CCN(CC5)C(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL458865', 'parent_molecule_chembl_id': 'CHEMBL458865', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583375, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8094917, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1nc(c2ccccc2)n3nc(NCCCN4CCOCC4)ncc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL486124', 'parent_molecule_chembl_id': 'CHEMBL486124', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583280, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8095281, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1)c3ccnc(Nc4cccc(c4)S(=O)(=O)N)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188381', 'parent_molecule_chembl_id': 'CHEMBL188381', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '71.91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583601, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '71.91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8095484, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909385', 'parent_molecule_chembl_id': 'CHEMBL213342', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583480, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8095625, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCN1CCC=C(C1)c2ccc(Nc3nc(Nc4ccccc4C(=O)N)c5cc[nH]c5n3)c(C)c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL513897', 'parent_molecule_chembl_id': 'CHEMBL513897', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.01', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583431, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.01', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8095849, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCN1CCC=C(C1)c2ccc(Nc3nc(Nc4ccccc4C(=O)N)c5cc[nH]c5n3)c(C)c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL513897', 'parent_molecule_chembl_id': 'CHEMBL513897', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583431, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8095997, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1cc2ncnc(Nc3ccc4c(cnn4Cc5ccccc5)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909380', 'parent_molecule_chembl_id': 'CHEMBL416031', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583438, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8096338, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5cccc(c5)C(F)(F)F)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275666', 'parent_molecule_chembl_id': 'CHEMBL275666', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583300, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8096477, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccccc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275798', 'parent_molecule_chembl_id': 'CHEMBL275798', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-3.16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583291, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-3.16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8096701, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.[O-][S+]1CCN(Cc2oc(cc2)c3ccc4ncnc(Nc5ccc(OCc6ccccc6)c(Cl)c5)c4c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909393', 'parent_molecule_chembl_id': 'CHEMBL212965', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583509, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8096857, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCc1cc(cs1)c2cc3c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)ncnc3s2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL475599', 'parent_molecule_chembl_id': 'CHEMBL475599', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583402, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8097004, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)c5cccs5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL506414', 'parent_molecule_chembl_id': 'CHEMBL506414', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.27', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583549, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.27', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8097228, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)c5cccs5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL506414', 'parent_molecule_chembl_id': 'CHEMBL506414', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583549, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8097315, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2ncn(c3cc(O[C@H](C)c4ccccc4Cl)c(s3)C(=O)N)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL493326', 'parent_molecule_chembl_id': 'CHEMBL493326', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583404, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8097535, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCCCNc1nccc(n1)c2c(nn3cc(ccc23)C(F)(F)F)c4ccc(F)cc4.OC(=O)\\C=C\\C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909403', 'parent_molecule_chembl_id': 'CHEMBL1952232', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583492, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8097685, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nc(OC[C@@H](N)c3ccccc3)cc12)C#CC(C)(C)O)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1096626', 'parent_molecule_chembl_id': 'CHEMBL1096626', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583424, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8097909, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nc(OC[C@@H](N)c3ccccc3)cc12)C#CC(C)(C)O)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1096626', 'parent_molecule_chembl_id': 'CHEMBL1096626', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583424, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8098042, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4cccc(c4)C(=O)O)cc3)ccc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909373', 'parent_molecule_chembl_id': 'CHEMBL244097', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.6', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583558, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.6', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8098386, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(COc2cc(sc2C(=O)N)n3cnc4ccccc34)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL516248', 'parent_molecule_chembl_id': 'CHEMBL516248', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.24', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583598, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.24', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8098566, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1cc(cc(C)c1\\C=C\\c2cncc(c2)c3nn[nH]n3)c4occc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909353', 'parent_molecule_chembl_id': 'CHEMBL373576', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583479, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8098975, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2nc(Nc3ccc(F)cc3C(=O)N)c4cc[nH]c4n2)N5CCN(CC5)C(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL458865', 'parent_molecule_chembl_id': 'CHEMBL458865', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583375, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8099119, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1coc(c1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909386', 'parent_molecule_chembl_id': 'CHEMBL377437', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.06', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583488, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.06', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8099485, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(=O)C)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL471789', 'parent_molecule_chembl_id': 'CHEMBL471789', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583371, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8099679, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2nn3cc(ccc3c2c4ccnc(NC5CC5)n4)C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1885746', 'parent_molecule_chembl_id': 'CHEMBL1885746', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583487, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8100050, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccc(C)cc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL303687', 'parent_molecule_chembl_id': 'CHEMBL303687', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '64.21', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583629, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '64.21', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8100196, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1cc2ncnc(Nc3ccc4c(cnn4Cc5ccccc5)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909380', 'parent_molecule_chembl_id': 'CHEMBL416031', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583438, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8100536, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5cccc(c5)C(F)(F)F)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275666', 'parent_molecule_chembl_id': 'CHEMBL275666', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.03', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583300, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.03', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8100900, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.[O-][S+]1CCN(Cc2oc(cc2)c3ccc4ncnc(Nc5ccc(OCc6ccccc6)c(Cl)c5)c4c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909393', 'parent_molecule_chembl_id': 'CHEMBL212965', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583509, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8101060, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1C(=O)N)c2ccncc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL231013', 'parent_molecule_chembl_id': 'CHEMBL231013', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583416, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8101426, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2oc(cn2)c3ccccc3)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL443563', 'parent_molecule_chembl_id': 'CHEMBL443563', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.54', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583523, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.54', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8101611, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2ncn(c3cc(O[C@H](C)c4ccccc4Cl)c(s3)C(=O)N)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL493326', 'parent_molecule_chembl_id': 'CHEMBL493326', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583404, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8101864, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)c2c[nH]c3c(N\\N=C\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL206010', 'parent_molecule_chembl_id': 'CHEMBL206010', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '41.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583612, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '41.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8102243, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL251549', 'parent_molecule_chembl_id': 'CHEMBL251549', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '69.13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583580, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '69.13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8102374, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4cccc(c4)C(=O)O)cc3)ccc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909373', 'parent_molecule_chembl_id': 'CHEMBL244097', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583558, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8102598, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)S(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3ccccc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275473', 'parent_molecule_chembl_id': 'CHEMBL275473', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.09', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583495, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.09', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8102718, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(COc2cc(sc2C(=O)N)n3cnc4ccccc34)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL516248', 'parent_molecule_chembl_id': 'CHEMBL516248', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583598, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8102896, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(Oc1ccc(Nc2ncnc3ccc(cc23)c4occc4)cc1)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL215993', 'parent_molecule_chembl_id': 'CHEMBL215993', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583441, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8103120, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(Oc1ccc(Nc2ncnc3ccc(cc23)c4occc4)cc1)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL215993', 'parent_molecule_chembl_id': 'CHEMBL215993', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.34', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583441, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.34', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8103316, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nc(OC[C@H](N)c3ccccc3)cc12)C#CC(C)(C)O)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1096634', 'parent_molecule_chembl_id': 'CHEMBL1096634', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.63', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583425, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.63', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8103454, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1coc(c1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909386', 'parent_molecule_chembl_id': 'CHEMBL377437', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583488, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8103678, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NC(=O)c1cccc(Nc2nccc(Nc3cccc(F)c3)n2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909382', 'parent_molecule_chembl_id': 'CHEMBL400388', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583566, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8103828, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(=O)C)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL471789', 'parent_molecule_chembl_id': 'CHEMBL471789', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583371, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8104013, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2nn3cc(ccc3c2c4ccnc(NC5CC5)n4)C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1885746', 'parent_molecule_chembl_id': 'CHEMBL1885746', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583487, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8104237, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)cc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909364', 'parent_molecule_chembl_id': 'CHEMBL396283', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.27', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583511, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.27', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8104385, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccc(C)cc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL303687', 'parent_molecule_chembl_id': 'CHEMBL303687', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '40.52', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583629, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '40.52', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8104531, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(cc23)c4ocnc4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL269827', 'parent_molecule_chembl_id': 'CHEMBL269827', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583434, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8104755, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(cc23)c4ocnc4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL269827', 'parent_molecule_chembl_id': 'CHEMBL269827', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583434, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8104869, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc(cc5)C#N)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL13972', 'parent_molecule_chembl_id': 'CHEMBL13972', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.9', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583295, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8105233, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc(Cl)cc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275168', 'parent_molecule_chembl_id': 'CHEMBL275168', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583306, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8105399, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1C(=O)N)c2ccncc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL231013', 'parent_molecule_chembl_id': 'CHEMBL231013', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583416, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8105623, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(OC4CCN(C)CC4)cc23)c5ccccc5Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794070', 'parent_molecule_chembl_id': 'CHEMBL1794070', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583414, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8105761, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2oc(cn2)c3ccccc3)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL443563', 'parent_molecule_chembl_id': 'CHEMBL443563', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '52.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583523, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '52.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8106041, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)Nc1cccc(c1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL205798', 'parent_molecule_chembl_id': 'CHEMBL205798', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583559, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8106206, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)c2c[nH]c3c(N\\N=C\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL206010', 'parent_molecule_chembl_id': 'CHEMBL206010', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '78.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583612, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '78.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8106430, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCCNc1nccc(n1)c2c(nn3cc(ccc23)C(F)(F)F)c4ccc(F)cc4.CS(=O)(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909405', 'parent_molecule_chembl_id': 'CHEMBL1896047', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583517, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8106586, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL251549', 'parent_molecule_chembl_id': 'CHEMBL251549', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '88.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583580, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '88.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8106939, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)S(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3ccccc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275473', 'parent_molecule_chembl_id': 'CHEMBL275473', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '36.61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583495, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '36.61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8107060, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1cc(c2ccnc3[nH]ccc23)c(n1)c4cccc(NC(=O)Nc5ccc(OCc6ccccc6)cc5)c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL505187', 'parent_molecule_chembl_id': 'CHEMBL505187', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583423, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8107456, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1sc(cc1OCc2ccccc2Br)n3cnc4cc(ccc34)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL480371', 'parent_molecule_chembl_id': 'CHEMBL480371', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583276, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8107657, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nc(OC[C@H](N)c3ccccc3)cc12)C#CC(C)(C)O)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1096634', 'parent_molecule_chembl_id': 'CHEMBL1096634', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.84', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583425, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.84', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8108016, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NC(=O)c1cccc(Nc2nccc(Nc3cccc(F)c3)n2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909382', 'parent_molecule_chembl_id': 'CHEMBL400388', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '51.88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583566, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '51.88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8108174, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1sc(cc1OCc2ccccc2C(F)(F)F)n3cnc4cc(OC)c(OC)cc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL518968', 'parent_molecule_chembl_id': 'CHEMBL518968', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583372, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8108573, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)cc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909364', 'parent_molecule_chembl_id': 'CHEMBL396283', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '28.78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583511, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '28.78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8108720, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(OCC4CCN(C)CC4)cc23)c5ccccc5Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794069', 'parent_molecule_chembl_id': 'CHEMBL1794069', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.53', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583413, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.53', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8109086, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)c5oc(COCCS(=O)(=O)c6ccccc6)cc5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL212250', 'parent_molecule_chembl_id': 'CHEMBL212250', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583515, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8109200, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc(cc5)C#N)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL13972', 'parent_molecule_chembl_id': 'CHEMBL13972', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583295, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8109424, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)c1C.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909400', 'parent_molecule_chembl_id': 'CHEMBL14212', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583307, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8109554, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc(Cl)cc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275168', 'parent_molecule_chembl_id': 'CHEMBL275168', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583306, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8109949, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(OC4CCN(C)CC4)cc23)c5ccccc5Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794070', 'parent_molecule_chembl_id': 'CHEMBL1794070', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583414, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8110081, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2oc(cn2)c3ccccc3)cc(OC)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL176553', 'parent_molecule_chembl_id': 'CHEMBL176553', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.68', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583525, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.68', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8110360, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)Nc1cccc(c1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL205798', 'parent_molecule_chembl_id': 'CHEMBL205798', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583559, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8110750, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCCNc1nccc(n1)c2c(nn3cc(ccc23)C(F)(F)F)c4ccc(F)cc4.CS(=O)(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909405', 'parent_molecule_chembl_id': 'CHEMBL1896047', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.34', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583517, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.34', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8110908, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OCCCN)c12)C#CCN)c3nonc3N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794064', 'parent_molecule_chembl_id': 'CHEMBL494280', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.47', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583412, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.47', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8111255, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1cccc(NC(=O)Nc2ccc(Oc3ccc4nc(NC(=O)OC)[nH]c4c3)cc2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL243907', 'parent_molecule_chembl_id': 'CHEMBL243907', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '14.82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583538, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '14.82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8111382, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1cc(c2ccnc3[nH]ccc23)c(n1)c4cccc(NC(=O)Nc5ccc(OCc6ccccc6)cc5)c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL505187', 'parent_molecule_chembl_id': 'CHEMBL505187', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583423, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8111606, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OC[C@@H]3CCCN3)c12)C#CC(C)(C)O)c4nonc4N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909375', 'parent_molecule_chembl_id': 'CHEMBL1963560', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583417, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8111772, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1sc(cc1OCc2ccccc2Br)n3cnc4cc(ccc34)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL480371', 'parent_molecule_chembl_id': 'CHEMBL480371', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583276, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8111977, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc(Nc2oc(cn2)c3ccccc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL192417', 'parent_molecule_chembl_id': 'CHEMBL192417', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583526, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8112338, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2nc(C)c3c(N\\N=C(/C)\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL442363', 'parent_molecule_chembl_id': 'CHEMBL442363', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583605, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8112506, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1sc(cc1OCc2ccccc2C(F)(F)F)n3cnc4cc(OC)c(OC)cc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL518968', 'parent_molecule_chembl_id': 'CHEMBL518968', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '13.25', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583372, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13.25', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8112730, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncc(c2cccc(c2)S(=O)(=O)N)c3scc(c4ccc(F)c(Cl)c4)c13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL241517', 'parent_molecule_chembl_id': 'CHEMBL241517', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '35.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583277, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '35.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8112902, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1ccoc1c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909388', 'parent_molecule_chembl_id': 'CHEMBL213822', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583491, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8113054, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(OCC4CCN(C)CC4)cc23)c5ccccc5Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794069', 'parent_molecule_chembl_id': 'CHEMBL1794069', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583413, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8113278, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCn1c(nc2c(nc(OCCNC)cc12)C#CC(C)(C)O)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909350', 'parent_molecule_chembl_id': 'CHEMBL1098943', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583426, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8113414, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)c5oc(COCCS(=O)(=O)c6ccccc6)cc5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL212250', 'parent_molecule_chembl_id': 'CHEMBL212250', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.65', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583515, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.65', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8113762, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)c1C.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909400', 'parent_molecule_chembl_id': 'CHEMBL14212', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583307, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8113878, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)CCc1ccccc1Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1785003', 'parent_molecule_chembl_id': 'CHEMBL1785003', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583304, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8114278, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(c5)C(F)(F)F)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909387', 'parent_molecule_chembl_id': 'CHEMBL214419', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.21', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583489, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.21', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8114410, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2oc(cn2)c3ccccc3)cc(OC)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL176553', 'parent_molecule_chembl_id': 'CHEMBL176553', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '29.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583525, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '29.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8114634, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)c5occc5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514938', 'parent_molecule_chembl_id': 'CHEMBL514938', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583428, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8114686, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1c2ccc(cc2)C(=O)NCC3CC3)C(=O)NC4CCCCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477978', 'parent_molecule_chembl_id': 'CHEMBL477978', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.04', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583581, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.04', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8114910, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1c2ccc(cc2)C(=O)NCC3CC3)C(=O)NC4CCCCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477978', 'parent_molecule_chembl_id': 'CHEMBL477978', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583581, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8115076, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Nc1ncnc2occ(c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL588025', 'parent_molecule_chembl_id': 'CHEMBL247228', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '25.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583570, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '25.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8115241, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OCCCN)c12)C#CCN)c3nonc3N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794064', 'parent_molecule_chembl_id': 'CHEMBL494280', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583412, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8115465, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)Nc1cccc(n1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL205765', 'parent_molecule_chembl_id': 'CHEMBL205765', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583591, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8115585, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1cccc(NC(=O)Nc2ccc(Oc3ccc4nc(NC(=O)OC)[nH]c4c3)cc2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL243907', 'parent_molecule_chembl_id': 'CHEMBL243907', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '44.77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583538, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '44.77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8115942, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OC[C@@H]3CCCN3)c12)C#CC(C)(C)O)c4nonc4N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909375', 'parent_molecule_chembl_id': 'CHEMBL1963560', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583417, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8116101, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(CO)CNC(=O)c1ccc2NC(=O)\\C(=N/Nc3ccc(cc3)S(=O)(=O)N)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL410072', 'parent_molecule_chembl_id': 'CHEMBL410072', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583449, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8116304, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc(Nc2oc(cn2)c3ccccc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL192417', 'parent_molecule_chembl_id': 'CHEMBL192417', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '18.01', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583526, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '18.01', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8116528, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OC3CCNCC3)c12)C#CC(C)(C)O)c4nonc4N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794066', 'parent_molecule_chembl_id': 'CHEMBL522857', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.02', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583418, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.02', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8116662, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2nc(C)c3c(N\\N=C(/C)\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL442363', 'parent_molecule_chembl_id': 'CHEMBL442363', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583605, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8117058, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncc(c2cccc(c2)S(=O)(=O)N)c3scc(c4ccc(F)c(Cl)c4)c13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL241517', 'parent_molecule_chembl_id': 'CHEMBL241517', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '78.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583277, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '78.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8117229, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1ccoc1c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909388', 'parent_molecule_chembl_id': 'CHEMBL213822', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583491, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8117611, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCn1c(nc2c(nc(OCCNC)cc12)C#CC(C)(C)O)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909350', 'parent_molecule_chembl_id': 'CHEMBL1098943', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583426, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8117741, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL529066', 'parent_molecule_chembl_id': 'CHEMBL380247', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583498, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8118103, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc(F)c(F)c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1785004', 'parent_molecule_chembl_id': 'CHEMBL1785004', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.34', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583301, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.34', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8118219, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)CCc1ccccc1Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1785003', 'parent_molecule_chembl_id': 'CHEMBL1785003', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583304, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8118443, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1c(cc(cc1c2ccc(cc2)S(=O)(=O)N)c3ccc(Cl)cc3)C(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL268885', 'parent_molecule_chembl_id': 'CHEMBL268885', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583422, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8118615, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(c5)C(F)(F)F)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909387', 'parent_molecule_chembl_id': 'CHEMBL214419', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583489, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8118975, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)c5occc5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514938', 'parent_molecule_chembl_id': 'CHEMBL514938', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583428, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8119246, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(C)c(NC(=O)CN(C)C)cc1Nc2nc(Nc3cccc(F)c3C(=O)N)c4cc[nH]c4n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL511765', 'parent_molecule_chembl_id': 'CHEMBL511765', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583390, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8119405, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Nc1ncnc2occ(c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL588025', 'parent_molecule_chembl_id': 'CHEMBL247228', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '64.18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583570, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '64.18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8119796, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)Nc1cccc(n1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL205765', 'parent_molecule_chembl_id': 'CHEMBL205765', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583591, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8119915, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1nc(cs1)c2ccc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909355', 'parent_molecule_chembl_id': 'CHEMBL516375', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583482, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8120278, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2c(c3ccnc(Nc4ccc5OCCOc5c4)n3)c(nn2n1)c6ccc(cc6)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188247', 'parent_molecule_chembl_id': 'CHEMBL188247', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583269, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8120438, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(CO)CNC(=O)c1ccc2NC(=O)\\C(=N/Nc3ccc(cc3)S(=O)(=O)N)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL410072', 'parent_molecule_chembl_id': 'CHEMBL410072', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583449, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8120662, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.O=C(O[C@H]1CN[C@@H](C1)C#Cc2cc3ncnc(Nc4ccc5c(cnn5Cc6ccccc6)c4)c3s2)N7CCOCC7', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909408', 'parent_molecule_chembl_id': 'CHEMBL507821', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583385, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8120863, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OC3CCNCC3)c12)C#CC(C)(C)O)c4nonc4N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794066', 'parent_molecule_chembl_id': 'CHEMBL522857', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583418, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8120991, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)c1ccc2\\C(=N/Nc3ccc(cc3)S(=O)(=O)N)\\C(=O)Nc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL271594', 'parent_molecule_chembl_id': 'CHEMBL271594', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.65', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583446, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.65', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8121215, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)c1ccc2\\C(=N/Nc3ccc(cc3)S(=O)(=O)N)\\C(=O)Nc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL271594', 'parent_molecule_chembl_id': 'CHEMBL271594', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '25.69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583446, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '25.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8121387, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(F)(F)F.O=C(O[C@H]1CN[C@@H](C1)C#Cc2cc3ncnc(Nc4ccc(Cc5ccccc5)cc4)c3s2)N6CCOCC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909409', 'parent_molecule_chembl_id': 'CHEMBL455434', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583396, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8121554, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3cccc(CCc4ccncc4)c23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909399', 'parent_molecule_chembl_id': 'CHEMBL1794054', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583455, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8121941, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1sc(cc1OCc2ccccc2Br)n3cnc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL518953', 'parent_molecule_chembl_id': 'CHEMBL518953', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583369, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8122062, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL529066', 'parent_molecule_chembl_id': 'CHEMBL380247', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583498, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8122286, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2occ(c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL247228', 'parent_molecule_chembl_id': 'CHEMBL247228', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '23.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583571, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '23.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8122424, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc(F)c(F)c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1785004', 'parent_molecule_chembl_id': 'CHEMBL1785004', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583301, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8122768, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1c(cc(cc1c2ccc(cc2)S(=O)(=O)N)c3ccc(Cl)cc3)C(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL268885', 'parent_molecule_chembl_id': 'CHEMBL268885', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.9', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583422, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8122935, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5cccc(F)c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL14014', 'parent_molecule_chembl_id': 'CHEMBL14014', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583298, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8123301, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514499', 'parent_molecule_chembl_id': 'CHEMBL514499', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583272, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8123579, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(C)c(NC(=O)CN(C)C)cc1Nc2nc(Nc3cccc(F)c3C(=O)N)c4cc[nH]c4n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL511765', 'parent_molecule_chembl_id': 'CHEMBL511765', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.02', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583390, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.02', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8123729, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(C=NNc2ncnc3c2cnn3c4ccccc4)ccc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1789961', 'parent_molecule_chembl_id': 'CHEMBL1789961', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583483, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8123953, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(C=NNc2ncnc3c2cnn3c4ccccc4)ccc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1789961', 'parent_molecule_chembl_id': 'CHEMBL1789961', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '71.51', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583483, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '71.51', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8124120, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2cnc3c(N\\N=C\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL204934', 'parent_molecule_chembl_id': 'CHEMBL204934', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583611, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8124239, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1nc(cs1)c2ccc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909355', 'parent_molecule_chembl_id': 'CHEMBL516375', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.66', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583482, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.66', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8124463, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(Nc2nccc(n2)c3cnn4ncccc34)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL187081', 'parent_molecule_chembl_id': 'CHEMBL187081', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583608, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8124602, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2c(c3ccnc(Nc4ccc5OCCOc5c4)n3)c(nn2n1)c6ccc(cc6)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188247', 'parent_molecule_chembl_id': 'CHEMBL188247', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583269, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8124991, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.O=C(O[C@H]1CN[C@@H](C1)C#Cc2cc3ncnc(Nc4ccc5c(cnn5Cc6ccccc6)c4)c3s2)N7CCOCC7', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909408', 'parent_molecule_chembl_id': 'CHEMBL507821', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.25', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583385, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.25', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8125192, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL428877', 'parent_molecule_chembl_id': 'CHEMBL428877', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583294, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8125546, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(F)(F)F.O=C(Nc1n[nH]c2nnc(cc12)c3cccnc3)C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909343', 'parent_molecule_chembl_id': 'CHEMBL35785', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583330, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8125714, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(F)(F)F.O=C(O[C@H]1CN[C@@H](C1)C#Cc2cc3ncnc(Nc4ccc(Cc5ccccc5)cc4)c3s2)N6CCOCC6', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909409', 'parent_molecule_chembl_id': 'CHEMBL455434', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583396, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8125878, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3cccc(CCc4ccncc4)c23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909399', 'parent_molecule_chembl_id': 'CHEMBL1794054', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583455, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8126102, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCN1CCC(CC1)C(=O)Nc2n[nH]c3nnc(cc23)c4cccc(F)c4F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909345', 'parent_molecule_chembl_id': 'CHEMBL39300', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583333, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8126266, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1sc(cc1OCc2ccccc2Br)n3cnc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL518953', 'parent_molecule_chembl_id': 'CHEMBL518953', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.23', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583369, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.23', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8126605, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2occ(c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL247228', 'parent_molecule_chembl_id': 'CHEMBL247228', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '56.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583571, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '56.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8126741, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\C=C\\2/C(=O)Nc3ccc4ncsc4c23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL271595', 'parent_molecule_chembl_id': 'CHEMBL271595', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583445, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8127087, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc(Oc6ccccc6)cc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL13868', 'parent_molecule_chembl_id': 'CHEMBL13868', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583296, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8127254, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5cccc(F)c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL14014', 'parent_molecule_chembl_id': 'CHEMBL14014', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583298, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8127478, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3cccc(F)c3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL179465', 'parent_molecule_chembl_id': 'CHEMBL179465', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '32.8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583521, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '32.8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8127620, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4C(F)(F)F)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514499', 'parent_molecule_chembl_id': 'CHEMBL514499', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '13.24', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583272, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13.24', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8127908, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2ncc3c(C)nc(c4cccc(Oc5ccccc5)c4)n3n2)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL519881', 'parent_molecule_chembl_id': 'CHEMBL519881', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583278, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8128284, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C(=O)c1cncc(\\C=C\\c2c(C)cc(O)cc2C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL220244', 'parent_molecule_chembl_id': 'CHEMBL220244', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583464, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8128451, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2cnc3c(N\\N=C\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL204934', 'parent_molecule_chembl_id': 'CHEMBL204934', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '59.45', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583611, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '59.45', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8128794, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(Nc2nccc(n2)c3cnn4ncccc34)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL187081', 'parent_molecule_chembl_id': 'CHEMBL187081', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '44.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583608, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '44.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8128931, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Cl)cc(NC2=C(C(=O)NC2=O)c3cccc(c3)[N+](=O)[O-])cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL352222', 'parent_molecule_chembl_id': 'CHEMBL352222', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583311, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8129155, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Cl)cc(NC2=C(C(=O)NC2=O)c3cccc(c3)[N+](=O)[O-])cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL352222', 'parent_molecule_chembl_id': 'CHEMBL352222', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583311, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8129326, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(C)CCOc1ccc(cc1)c2oc(c3ccncc3)c(c2)c4ccc5C(=NO)CCc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794072', 'parent_molecule_chembl_id': 'CHEMBL1852436', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583332, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8129515, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL428877', 'parent_molecule_chembl_id': 'CHEMBL428877', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.01', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583294, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.01', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8129878, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(F)(F)F.O=C(Nc1n[nH]c2nnc(cc12)c3cccnc3)C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909343', 'parent_molecule_chembl_id': 'CHEMBL35785', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583330, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8130039, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)CNc1nccc(n1)c2cnn3ncccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL446024', 'parent_molecule_chembl_id': 'CHEMBL446024', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583545, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8130435, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCN1CCC(CC1)C(=O)Nc2n[nH]c3nnc(cc23)c4cccc(F)c4F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909345', 'parent_molecule_chembl_id': 'CHEMBL39300', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583333, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8130595, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)Cc1ccc(Nc2nccc(n2)c3cnn4ncccc34)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1882194', 'parent_molecule_chembl_id': 'CHEMBL1882194', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.47', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583577, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.47', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8130935, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)c1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL418348', 'parent_molecule_chembl_id': 'CHEMBL418348', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583302, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8131074, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\C=C\\2/C(=O)Nc3ccc4ncsc4c23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL271595', 'parent_molecule_chembl_id': 'CHEMBL271595', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '21.77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583445, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '21.77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8131298, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccccc1Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL417804', 'parent_molecule_chembl_id': 'CHEMBL417804', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583299, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8131418, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc(Oc6ccccc6)cc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL13868', 'parent_molecule_chembl_id': 'CHEMBL13868', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583296, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8131809, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3cccc(F)c3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL179465', 'parent_molecule_chembl_id': 'CHEMBL179465', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '74.59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583521, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '74.59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8131950, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2occ(c3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL273564', 'parent_molecule_chembl_id': 'CHEMBL273564', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '33.61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583593, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '33.61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8132236, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2ncc3c(C)nc(c4cccc(Oc5ccccc5)c4)n3n2)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL519881', 'parent_molecule_chembl_id': 'CHEMBL519881', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583278, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8132607, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C(=O)c1cncc(\\C=C\\c2c(C)cc(O)cc2C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL220244', 'parent_molecule_chembl_id': 'CHEMBL220244', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583464, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8132775, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cncc(\\C=C\\c2ccccc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218970', 'parent_molecule_chembl_id': 'CHEMBL218970', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583477, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8133120, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(CNc2nccc(n2)c3cnn4ncccc34)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL513330', 'parent_molecule_chembl_id': 'CHEMBL513330', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583579, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8133482, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1CCC(CC(=O)Nc2n[nH]c3nnc(cc23)c4cccc(F)c4F)CC1.OC(C(O)C(=O)O)C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2062289', 'parent_molecule_chembl_id': 'CHEMBL38425', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583334, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8133654, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(C)CCOc1ccc(cc1)c2oc(c3ccncc3)c(c2)c4ccc5C(=NO)CCc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794072', 'parent_molecule_chembl_id': 'CHEMBL1852436', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '18.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583332, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '18.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8133834, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(c1ccc(NC(=O)Nc2ccc(cc2)C(=O)N3CCN(C)CC3)cc1)c4ccnc(Nc5ccc(CS(=O)(=O)C)cc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909360', 'parent_molecule_chembl_id': 'CHEMBL187494', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '21.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583631, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '21.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8134058, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(c1ccc(NC(=O)Nc2ccc(cc2)C(=O)N3CCN(C)CC3)cc1)c4ccnc(Nc5ccc(CS(=O)(=O)C)cc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909360', 'parent_molecule_chembl_id': 'CHEMBL187494', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '56.54', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583631, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '56.54', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8134206, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2oc3ncnc(N)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL373073', 'parent_molecule_chembl_id': 'CHEMBL373073', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583531, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8134366, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)CNc1nccc(n1)c2cnn3ncccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL446024', 'parent_molecule_chembl_id': 'CHEMBL446024', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583545, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8134590, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2cocc2)cc1c3ccc(cc3)C(=O)NCC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477583', 'parent_molecule_chembl_id': 'CHEMBL477583', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583565, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8134774, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)Nc1ccc(N\\C=C\\2/C(=O)Nc3ccccc23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794058', 'parent_molecule_chembl_id': 'CHEMBL1794058', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583435, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8134934, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)Cc1ccc(Nc2nccc(n2)c3cnn4ncccc34)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1882194', 'parent_molecule_chembl_id': 'CHEMBL1882194', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '22.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583577, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '22.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8135158, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1cc(cc(C)c1\\C=C\\c2cncc(c2)c3nn[nH]n3)c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909354', 'parent_molecule_chembl_id': 'CHEMBL374680', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583481, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8135273, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)c1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL418348', 'parent_molecule_chembl_id': 'CHEMBL418348', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.04', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583302, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.04', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8135638, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccccc1Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL417804', 'parent_molecule_chembl_id': 'CHEMBL417804', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.54', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583299, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.54', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8135759, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL269450', 'parent_molecule_chembl_id': 'CHEMBL269450', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583292, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8135983, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL269450', 'parent_molecule_chembl_id': 'CHEMBL269450', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583292, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8136151, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(\\C=N\\Nc2ncnc3c2cnn3c4cccc(OC)c4)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL305477', 'parent_molecule_chembl_id': 'CHEMBL305477', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583628, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8136295, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2occ(c3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL273564', 'parent_molecule_chembl_id': 'CHEMBL273564', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '64.69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583593, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '64.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8136519, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc6OCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL273611', 'parent_molecule_chembl_id': 'CHEMBL273611', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.06', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583297, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.06', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8136585, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(C)c(cc1Nc2nc(Nc3cccc(F)c3C(=O)N)c4cc[nH]c4n2)N(C)C(=O)CN(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL467581', 'parent_molecule_chembl_id': 'CHEMBL467581', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.32', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583391, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.32', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8136809, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(C)c(cc1Nc2nc(Nc3cccc(F)c3C(=O)N)c4cc[nH]c4n2)N(C)C(=O)CN(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL467581', 'parent_molecule_chembl_id': 'CHEMBL467581', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-3.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583391, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-3.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8136944, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(CC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)Nc3ccc4[nH]ncc4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL374453', 'parent_molecule_chembl_id': 'CHEMBL374453', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583401, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8137107, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cncc(\\C=C\\c2ccccc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218970', 'parent_molecule_chembl_id': 'CHEMBL218970', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '21.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583477, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '21.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8137331, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCNc1cccc(c1)n2ncc3c(N\\N=C\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL67241', 'parent_molecule_chembl_id': 'CHEMBL67241', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583590, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8137451, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(CNc2nccc(n2)c3cnn4ncccc34)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL513330', 'parent_molecule_chembl_id': 'CHEMBL513330', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583579, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8137823, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1CCC(CC(=O)Nc2n[nH]c3nnc(cc23)c4cccc(F)c4F)CC1.OC(C(O)C(=O)O)C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2062289', 'parent_molecule_chembl_id': 'CHEMBL38425', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583334, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8137989, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccccc1C(=O)Nc2sc3CCCCc3c2C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL234838', 'parent_molecule_chembl_id': 'CHEMBL234838', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583496, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8138392, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1nc(cs1)c2ccc3ncnc(Nc4ccc(OCc5cccc(c5)C(F)(F)F)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909356', 'parent_molecule_chembl_id': 'CHEMBL505970', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583493, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8138540, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2oc3ncnc(N)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL373073', 'parent_molecule_chembl_id': 'CHEMBL373073', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583531, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8138922, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2cocc2)cc1c3ccc(cc3)C(=O)NCC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477583', 'parent_molecule_chembl_id': 'CHEMBL477583', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583565, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8139107, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)Nc1ccc(N\\C=C\\2/C(=O)Nc3ccccc23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794058', 'parent_molecule_chembl_id': 'CHEMBL1794058', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583435, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8139490, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1cc(cc(C)c1\\C=C\\c2cncc(c2)c3nn[nH]n3)c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909354', 'parent_molecule_chembl_id': 'CHEMBL374680', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '20.18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583481, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '20.18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8139604, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)c(c4)C(F)(F)F)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909389', 'parent_molecule_chembl_id': 'CHEMBL387207', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583497, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8139828, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)c(c4)C(F)(F)F)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909389', 'parent_molecule_chembl_id': 'CHEMBL387207', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583497, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8139969, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(F)(F)F.[O-][S+]1CCN(Cc2oc(cc2)c3ccc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909390', 'parent_molecule_chembl_id': 'CHEMBL212954', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.01', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583502, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.01', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8140316, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[Li+].[O-]C(=O)c1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909401', 'parent_molecule_chembl_id': 'CHEMBL14233', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583308, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8140475, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(\\C=N\\Nc2ncnc3c2cnn3c4cccc(OC)c4)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL305477', 'parent_molecule_chembl_id': 'CHEMBL305477', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '15.16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583628, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '15.16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8140842, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ncn(C3CCNCC3)c2c4ccnc(Oc5ccc6OCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL273611', 'parent_molecule_chembl_id': 'CHEMBL273611', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583297, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8141144, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2CCN(C(=O)CN(C)C)c2cc1Nc3nc(N4CCc5ccccc45)c6cc[nH]c6n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL458415', 'parent_molecule_chembl_id': 'CHEMBL458415', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.02', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583389, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.02', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8141274, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(CC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)Nc3ccc4[nH]ncc4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL374453', 'parent_molecule_chembl_id': 'CHEMBL374453', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583401, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8141658, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCNc1cccc(c1)n2ncc3c(N\\N=C\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL67241', 'parent_molecule_chembl_id': 'CHEMBL67241', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '61.86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583590, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '61.86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8141777, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cncc(\\C=C\\c2c(C)cccc2C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218859', 'parent_molecule_chembl_id': 'CHEMBL218859', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.09', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583474, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.09', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8142001, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cncc(\\C=C\\c2c(C)cccc2C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218859', 'parent_molecule_chembl_id': 'CHEMBL218859', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '51.33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583474, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '51.33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8142162, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc6OCCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188257', 'parent_molecule_chembl_id': 'CHEMBL188257', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.47', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583622, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.47', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8142330, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccccc1C(=O)Nc2sc3CCCCc3c2C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL234838', 'parent_molecule_chembl_id': 'CHEMBL234838', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583496, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8142554, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(OCC4CCN(C)CC4)cc23)c5ccccc5C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794068', 'parent_molecule_chembl_id': 'CHEMBL1794068', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583408, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8142730, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1nc(cs1)c2ccc3ncnc(Nc4ccc(OCc5cccc(c5)C(F)(F)F)cc4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909356', 'parent_molecule_chembl_id': 'CHEMBL505970', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583493, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8142879, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)NC(=O)c1ccc(C)c(c1)c2ccc(cc2)C(=O)NCC3CC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477979', 'parent_molecule_chembl_id': 'CHEMBL477979', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.09', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583588, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.09', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8143103, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)NC(=O)c1ccc(C)c(c1)c2ccc(cc2)C(=O)NCC3CC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477979', 'parent_molecule_chembl_id': 'CHEMBL477979', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583588, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8143258, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ccc(cc1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL205966', 'parent_molecule_chembl_id': 'CHEMBL205966', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583537, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8143445, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Br)cc(C=C2C(=O)Nc3ccc(I)cc23)cc1Br', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1880739', 'parent_molecule_chembl_id': 'CHEMBL1880739', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583452, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8143669, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Br)cc(C=C2C(=O)Nc3ccc(I)cc23)cc1Br', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1880739', 'parent_molecule_chembl_id': 'CHEMBL1880739', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.48', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583452, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.48', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8143828, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2c(c3ccnc(Nc4cccc(c4)C(F)(F)F)n3)c(nn2n1)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL434729', 'parent_molecule_chembl_id': 'CHEMBL434729', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-9.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583630, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-9.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8144166, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)c(Br)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909392', 'parent_molecule_chembl_id': 'CHEMBL214689', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583506, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8144305, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(F)(F)F.[O-][S+]1CCN(Cc2oc(cc2)c3ccc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4c3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909390', 'parent_molecule_chembl_id': 'CHEMBL212954', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.14', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583502, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8144659, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[Li+].[O-]C(=O)c1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909401', 'parent_molecule_chembl_id': 'CHEMBL14233', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583308, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8144812, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cc(cc(c1N)c2ccc(cc2)S(=O)(=O)N3CCCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL230592', 'parent_molecule_chembl_id': 'CHEMBL230592', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583421, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8145036, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cc(cc(c1N)c2ccc(cc2)S(=O)(=O)N3CCCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL230592', 'parent_molecule_chembl_id': 'CHEMBL230592', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583421, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8145173, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)c5oc(CNCCS(=O)(=O)c6ccccc6)cc5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909395', 'parent_molecule_chembl_id': 'CHEMBL1794063', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583528, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8145486, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2CCN(C(=O)CN(C)C)c2cc1Nc3nc(N4CCc5ccccc45)c6cc[nH]c6n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL458415', 'parent_molecule_chembl_id': 'CHEMBL458415', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583389, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8145610, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1n[nH]c2nc(ccc12)c3occc3)C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL101804', 'parent_molecule_chembl_id': 'CHEMBL101804', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583353, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8145834, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1n[nH]c2nc(ccc12)c3occc3)C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL101804', 'parent_molecule_chembl_id': 'CHEMBL101804', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583353, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8145995, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(c1ccc(NC(=O)Nc2c(Cl)cccc2Cl)cc1)c3ccnc(Nc4cccc(CS(=O)(=O)C)c4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189353', 'parent_molecule_chembl_id': 'CHEMBL189353', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '25.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583606, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '25.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8146339, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)Nc1nc2ccc(Sc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)cc2[nH]1.OS(=O)(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909365', 'parent_molecule_chembl_id': 'CHEMBL243912', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583512, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8146499, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc6OCCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188257', 'parent_molecule_chembl_id': 'CHEMBL188257', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '33.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583622, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '33.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8146890, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1cc(sc1C(=O)N)n2cnc3ccc(OCC4CCN(C)CC4)cc23)c5ccccc5C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794068', 'parent_molecule_chembl_id': 'CHEMBL1794068', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583408, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8147059, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)C(=O)Nc2n[nH]c3nc(c(Br)cc23)c4ccc(O)cc4.OC(=O)\\C=C/C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909347', 'parent_molecule_chembl_id': 'CHEMBL261129', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583338, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8147425, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(Nc2nccc(n2)c3cnn4nc(ccc34)c5ccccc5)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189415', 'parent_molecule_chembl_id': 'CHEMBL189415', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583615, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8147578, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ccc(cc1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL205966', 'parent_molecule_chembl_id': 'CHEMBL205966', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583537, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8147989, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)c1ccc2NC(=O)C(=Cc3cc(Br)c(O)c(Br)c3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794052', 'parent_molecule_chembl_id': 'CHEMBL1794052', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.66', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583457, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.66', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8148147, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2c(c3ccnc(Nc4cccc(c4)C(F)(F)F)n3)c(nn2n1)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL434729', 'parent_molecule_chembl_id': 'CHEMBL434729', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '33.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583630, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '33.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8148485, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5ccccc5)c(Br)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909392', 'parent_molecule_chembl_id': 'CHEMBL214689', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583506, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8148624, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275200', 'parent_molecule_chembl_id': 'CHEMBL275200', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583305, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8148848, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275200', 'parent_molecule_chembl_id': 'CHEMBL275200', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583305, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8148986, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275724', 'parent_molecule_chembl_id': 'CHEMBL275724', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583293, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8149369, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCN(CC#N)Cc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL384407', 'parent_molecule_chembl_id': 'CHEMBL384407', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583516, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8149503, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)c5oc(CNCCS(=O)(=O)c6ccccc6)cc5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909395', 'parent_molecule_chembl_id': 'CHEMBL1794063', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583528, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8149825, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)Oc1cc(C)c(\\C=C\\c2cncc(c2)C(=O)NC)c(C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218932', 'parent_molecule_chembl_id': 'CHEMBL218932', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583466, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8150174, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1ccc(cc1NC(=O)Nc2ccc(Oc3ccc4[nH]c(NC(=O)c5occc5)nc4c3)cc2)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909368', 'parent_molecule_chembl_id': 'CHEMBL244297', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '35.63', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583547, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '35.63', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8150334, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(c1ccc(NC(=O)Nc2c(Cl)cccc2Cl)cc1)c3ccnc(Nc4cccc(CS(=O)(=O)C)c4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189353', 'parent_molecule_chembl_id': 'CHEMBL189353', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '55.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583606, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '55.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8150678, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)Nc1nc2ccc(Sc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)cc2[nH]1.OS(=O)(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909365', 'parent_molecule_chembl_id': 'CHEMBL243912', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '58.91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583512, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '58.91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8150843, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2CCCN(C(=O)CN(C)C)c2cc1Nc3nc(Nc4ccsc4C(=O)N)c5cc[nH]c5n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL456252', 'parent_molecule_chembl_id': 'CHEMBL456252', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583387, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8151067, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2CCCN(C(=O)CN(C)C)c2cc1Nc3nc(Nc4ccsc4C(=O)N)c5cc[nH]c5n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL456252', 'parent_molecule_chembl_id': 'CHEMBL456252', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.21', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583387, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.21', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8151230, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1c2ccc3[nH]ncc3c2)C(=O)NC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL495902', 'parent_molecule_chembl_id': 'CHEMBL495902', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583617, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8151407, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)C(=O)Nc2n[nH]c3nc(c(Br)cc23)c4ccc(O)cc4.OC(=O)\\C=C/C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909347', 'parent_molecule_chembl_id': 'CHEMBL261129', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583338, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8151769, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(Nc2nccc(n2)c3cnn4nc(ccc34)c5ccccc5)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189415', 'parent_molecule_chembl_id': 'CHEMBL189415', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583615, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8151923, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5cccc(c5)C(F)(F)F)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL186213', 'parent_molecule_chembl_id': 'CHEMBL186213', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583621, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8152147, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5cccc(c5)C(F)(F)F)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL186213', 'parent_molecule_chembl_id': 'CHEMBL186213', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583621, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8152335, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)c1ccc2NC(=O)C(=Cc3cc(Br)c(O)c(Br)c3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794052', 'parent_molecule_chembl_id': 'CHEMBL1794052', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '15.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583457, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '15.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8152493, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N(c1ccccc1)c2oc(cn2)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL318728', 'parent_molecule_chembl_id': 'CHEMBL318728', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583485, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8152717, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N(c1ccccc1)c2oc(cn2)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL318728', 'parent_molecule_chembl_id': 'CHEMBL318728', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '22.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583485, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '22.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8152831, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCS(=O)(=O)c1ccc(OC)c(Nc2nccc(n2)N(C)c3ccc4c(C)n[nH]c4c3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909358', 'parent_molecule_chembl_id': 'CHEMBL475932', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '41.96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583535, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '41.96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8153194, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2oc(cc2)c3cc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4s3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL475761', 'parent_molecule_chembl_id': 'CHEMBL475761', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.03', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583584, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.03', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8153331, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc(Oc2nccc(n2)c3c(ncn3C4CCNCC4)c5ccc(F)cc5)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL275724', 'parent_molecule_chembl_id': 'CHEMBL275724', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583293, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8153712, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCN(CC#N)Cc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL384407', 'parent_molecule_chembl_id': 'CHEMBL384407', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583516, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8153845, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2cncc(C(=O)NCCNC)c12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL506153', 'parent_molecule_chembl_id': 'CHEMBL506153', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583281, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8154069, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2cncc(C(=O)NCCNC)c12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL506153', 'parent_molecule_chembl_id': 'CHEMBL506153', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583281, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8154166, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)Oc1cc(C)c(\\C=C\\c2cncc(c2)C(=O)NC)c(C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218932', 'parent_molecule_chembl_id': 'CHEMBL218932', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '64.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583466, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '64.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8154516, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1ccc(cc1NC(=O)Nc2ccc(Oc3ccc4[nH]c(NC(=O)c5occc5)nc4c3)cc2)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909368', 'parent_molecule_chembl_id': 'CHEMBL244297', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '66.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583547, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '66.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8154675, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cccc(c1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL207410', 'parent_molecule_chembl_id': 'CHEMBL207410', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583573, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8154899, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cccc(c1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL207410', 'parent_molecule_chembl_id': 'CHEMBL207410', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583573, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8155019, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccnc(c2)N3CCOCC3)cc1c4ccc(cc4)C(=O)NCC5CC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL476351', 'parent_molecule_chembl_id': 'CHEMBL476351', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583574, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8155419, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)c2c(nn3cc(ccc23)C(F)(F)F)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909402', 'parent_molecule_chembl_id': 'CHEMBL1909402', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583490, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8155580, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1c2ccc3[nH]ncc3c2)C(=O)NC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL495902', 'parent_molecule_chembl_id': 'CHEMBL495902', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583617, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8155758, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1nn2ncccc2c1c3ccnc(NC4CC4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL524057', 'parent_molecule_chembl_id': 'CHEMBL524057', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583548, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8155982, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1nn2ncccc2c1c3ccnc(NC4CC4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL524057', 'parent_molecule_chembl_id': 'CHEMBL524057', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583548, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8156120, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1ccc2c(cnn2n1)c3ccnc(Nc4cccc(c4)C(F)(F)F)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL183993', 'parent_molecule_chembl_id': 'CHEMBL183993', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.04', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583610, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.04', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8156332, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL381604', 'parent_molecule_chembl_id': 'CHEMBL381604', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583596, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8156556, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1)c2oc3ncnc(NC(=O)C4CC4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL182283', 'parent_molecule_chembl_id': 'CHEMBL182283', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583616, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8156706, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3cccc(c3)C(=O)C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191705', 'parent_molecule_chembl_id': 'CHEMBL191705', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '60.8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583519, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '60.8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8157073, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(Nc2oc(cn2)c3ccccc3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL194062', 'parent_molecule_chembl_id': 'CHEMBL194062', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '42.02', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583494, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '42.02', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8157193, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(CC(=O)N1)c2ccc(cc2)C(F)(F)F)C(=O)Nc3ccc4[nH]nc(C)c4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218720', 'parent_molecule_chembl_id': 'CHEMBL218720', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583409, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8157558, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2ncc3c(C)nc(c4cccc(c4)C(F)(F)F)n3n2)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL520037', 'parent_molecule_chembl_id': 'CHEMBL520037', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583271, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8157688, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1ccc(cc1NC(=O)Nc2ccc(Oc3ccc4[nH]c(NC(=O)c5ccccc5)nc4c3)cc2)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909374', 'parent_molecule_chembl_id': 'CHEMBL243917', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '65.89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583562, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '65.89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8157912, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccccc1C2=C(Nc3ccccc3)C(=O)NC2=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL156263', 'parent_molecule_chembl_id': 'CHEMBL156263', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.45', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583314, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.45', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8158073, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261849', 'parent_molecule_chembl_id': 'CHEMBL261849', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583527, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8158323, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2cc(ccc2c1)c3c(nc(c4ccc(cc4C)S(=O)(=O)C)n3C)c5ccncc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL237571', 'parent_molecule_chembl_id': 'CHEMBL237571', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583328, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8158705, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccnc(c2)N3CCCC3)cc1c4ccc(cc4)C(=O)NCC5CC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477182', 'parent_molecule_chembl_id': 'CHEMBL477182', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583568, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8158874, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(F)c(c1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261440', 'parent_molecule_chembl_id': 'CHEMBL261440', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583341, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8159233, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncnc4cc(C#C[C@@H]5C[C@H](CN5)OC(=O)N6CCOCC6)sc34)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL507329', 'parent_molecule_chembl_id': 'CHEMBL507329', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583279, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8159353, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(CC(=O)N1)c2ccc(cc2)C(F)(F)F)C(=O)Nc3cc(Cl)c4[nH]ncc4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL427058', 'parent_molecule_chembl_id': 'CHEMBL427058', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.51', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583410, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.51', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8159577, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2c(nc3SCCn23)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL266707', 'parent_molecule_chembl_id': 'CHEMBL266707', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583363, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8159708, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(Nc2cc(n[nH]2)c3cccc(O)c3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103104', 'parent_molecule_chembl_id': 'CHEMBL103104', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.81', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583267, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.81', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8160073, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.C1Cc2nc(c3ccccn3)c(c4ccc5OCOc5c4)n2C1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909377', 'parent_molecule_chembl_id': 'CHEMBL268889', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583317, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8160210, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(=O)O.O=C(CN1CCOCC1)Nc2sc3CCCCc3c2C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909342', 'parent_molecule_chembl_id': 'CHEMBL232405', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.84', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583329, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.84', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8160584, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)c2c(ncn2C3CCC(O)CC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1888586', 'parent_molecule_chembl_id': 'CHEMBL1888586', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583288, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8160878, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1)c2oc3ncnc(NC(=O)C4CC4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL182283', 'parent_molecule_chembl_id': 'CHEMBL182283', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583616, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8161028, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(c1ccc(NC(=O)NCCN2CCOCC2)cc1)c3ccnc(Nc4ccc(CS(=O)(=O)C)cc4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909361', 'parent_molecule_chembl_id': 'CHEMBL363316', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.09', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583632, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.09', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8161395, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C1COc2cc(Nc3nccc(n3)c4cnn5ncccc45)ccc2O1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL361894', 'parent_molecule_chembl_id': 'CHEMBL361894', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.27', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583600, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.27', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8161520, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(CC(=O)N1)c2ccc(cc2)C(F)(F)F)C(=O)Nc3ccc4[nH]nc(C)c4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218720', 'parent_molecule_chembl_id': 'CHEMBL218720', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583409, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8161744, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cccc(NC2=C(C(=O)NC2=O)c3ccccc3Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL160937', 'parent_molecule_chembl_id': 'CHEMBL160937', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583316, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8161882, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2ncc3c(C)nc(c4cccc(c4)C(F)(F)F)n3n2)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL520037', 'parent_molecule_chembl_id': 'CHEMBL520037', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '13.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583271, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8162236, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccccc1C2=C(Nc3ccccc3)C(=O)NC2=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL156263', 'parent_molecule_chembl_id': 'CHEMBL156263', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583314, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8162396, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN1CCN(CCCNc2nc3ccc(Oc4ccc(NC(=O)Nc5cc(ccc5F)C(F)(F)F)cc4)cc3[nH]2)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909372', 'parent_molecule_chembl_id': 'CHEMBL1888322', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583556, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8162649, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCn1c(nc2cncc(C(=O)N3CC[C@H](N)C3)c12)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909384', 'parent_molecule_chembl_id': 'CHEMBL1956071', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583359, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8163021, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(NC=C2C(=O)Nc3ccc4ncsc4c23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794055', 'parent_molecule_chembl_id': 'CHEMBL1794055', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583510, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8163190, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(F)c(c1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261440', 'parent_molecule_chembl_id': 'CHEMBL261440', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '18.98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583341, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '18.98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8163414, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1sc2CCCCc2c1C#N)c3cccc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL233001', 'parent_molecule_chembl_id': 'CHEMBL233001', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583518, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8163548, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncnc4cc(C#C[C@@H]5C[C@H](CN5)OC(=O)N6CCOCC6)sc34)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL507329', 'parent_molecule_chembl_id': 'CHEMBL507329', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.68', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583279, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.68', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8163895, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2c(nc3SCCn23)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL266707', 'parent_molecule_chembl_id': 'CHEMBL266707', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583363, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8164029, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCN1CCCC(C1)c2ccc(Nc3nc(Nc4cc(F)ccc4C(=O)N)c5cc[nH]c5n3)c(OC)c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477069', 'parent_molecule_chembl_id': 'CHEMBL477069', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583374, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8164393, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1(C)CC(CC(C)(C)N1)n2cnc(c3ccc(F)cc3)c2c4ccnc(N)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL95502', 'parent_molecule_chembl_id': 'CHEMBL95502', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583287, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8164548, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(=O)O.O=C(CN1CCOCC1)Nc2sc3CCCCc3c2C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909342', 'parent_molecule_chembl_id': 'CHEMBL232405', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.84', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583329, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.84', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8164772, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N#Cc1cccc(Nc2nccc(n2)c3cnn4ncccc34)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL495696', 'parent_molecule_chembl_id': 'CHEMBL495696', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583575, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8164916, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)c2c(ncn2C3CCC(O)CC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1888586', 'parent_molecule_chembl_id': 'CHEMBL1888586', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '30.34', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583288, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '30.34', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8165210, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1ncccc1Nc2nc(Nc3cc4N(CCCc4cc3OC)C(=O)CN(C)C)nc5[nH]ccc25', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1895450', 'parent_molecule_chembl_id': 'CHEMBL1895450', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.06', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583392, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.06', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8165351, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(c1ccc(NC(=O)NCCN2CCOCC2)cc1)c3ccnc(Nc4ccc(CS(=O)(=O)C)cc4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909361', 'parent_molecule_chembl_id': 'CHEMBL363316', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '36.03', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583632, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '36.03', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8165575, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Cl)cc(NC2=C(C(=O)NC2=O)c3ccccc3Cl)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL157258', 'parent_molecule_chembl_id': 'CHEMBL157258', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583315, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8165718, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C1COc2cc(Nc3nccc(n3)c4cnn5ncccc45)ccc2O1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL361894', 'parent_molecule_chembl_id': 'CHEMBL361894', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '43.89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583600, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '43.89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8166068, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cccc(NC2=C(C(=O)NC2=O)c3ccccc3Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL160937', 'parent_molecule_chembl_id': 'CHEMBL160937', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583316, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8166206, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NS(=O)(=O)c1cccc(Nc2cc(n[nH]2)c3ccc(F)cc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909351', 'parent_molecule_chembl_id': 'CHEMBL329040', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583618, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8166560, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Oc1cccc(c1)c2nc([nH]c2c3ccncc3)c4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909413', 'parent_molecule_chembl_id': 'CHEMBL304624', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '13.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583325, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8166885, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2nccc(Nc3ccc4c(C)n[nH]c4c3)n2)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL479079', 'parent_molecule_chembl_id': 'CHEMBL479079', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '69.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583514, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '69.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8166973, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCn1c(nc2cncc(C(=O)N3CC[C@H](N)C3)c12)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909384', 'parent_molecule_chembl_id': 'CHEMBL1956071', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583359, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8167197, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCn1c(nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc12)c6nonc6N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909363', 'parent_molecule_chembl_id': 'CHEMBL220241', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583399, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8167338, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(NC=C2C(=O)Nc3ccc4ncsc4c23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794055', 'parent_molecule_chembl_id': 'CHEMBL1794055', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '31.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583510, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '31.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8167726, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1sc2CCCCc2c1C#N)c3cccc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL233001', 'parent_molecule_chembl_id': 'CHEMBL233001', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583518, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8167859, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2ccc(F)cc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL426800', 'parent_molecule_chembl_id': 'CHEMBL426800', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583586, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8168207, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(NC(=O)N1)c2ccc(F)cc2)C(=O)Nc3ccc4[nH]ncc4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL384073', 'parent_molecule_chembl_id': 'CHEMBL384073', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583381, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8168348, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCN1CCCC(C1)c2ccc(Nc3nc(Nc4cc(F)ccc4C(=O)N)c5cc[nH]c5n3)c(OC)c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477069', 'parent_molecule_chembl_id': 'CHEMBL477069', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583374, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8168572, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc2c(c3ccnc(NCCCO)n3)c(nn2c1)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909404', 'parent_molecule_chembl_id': 'CHEMBL1909404', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583508, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8168708, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1(C)CC(CC(C)(C)N1)n2cnc(c3ccc(F)cc3)c2c4ccnc(N)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL95502', 'parent_molecule_chembl_id': 'CHEMBL95502', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.01', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583287, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.01', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8169096, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N#Cc1cccc(Nc2nccc(n2)c3cnn4ncccc34)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL495696', 'parent_molecule_chembl_id': 'CHEMBL495696', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '44.32', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583575, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '44.32', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8169238, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)Nc1ccc(cc1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL102936', 'parent_molecule_chembl_id': 'CHEMBL102936', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583352, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8169542, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1ncccc1Nc2nc(Nc3cc4N(CCCc4cc3OC)C(=O)CN(C)C)nc5[nH]ccc25', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1895450', 'parent_molecule_chembl_id': 'CHEMBL1895450', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583392, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8169900, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Cl)cc(NC2=C(C(=O)NC2=O)c3ccccc3Cl)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL157258', 'parent_molecule_chembl_id': 'CHEMBL157258', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583315, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8170045, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2occ(c3ccc(NC(=O)Nc4cc(cc(c4)C(F)(F)F)C(F)(F)F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL396107', 'parent_molecule_chembl_id': 'CHEMBL396107', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583592, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8170394, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc2\\C(=N\\Nc3ccc(cc3)S(=O)(=O)N)\\C(=O)Nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909398', 'parent_molecule_chembl_id': 'CHEMBL1909398', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583439, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8170534, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.NS(=O)(=O)c1cccc(Nc2cc(n[nH]2)c3ccc(F)cc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909351', 'parent_molecule_chembl_id': 'CHEMBL329040', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583618, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8170758, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OCC3CCNCC3)c12)C#CC(C)(C)O)c4nonc4N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794065', 'parent_molecule_chembl_id': 'CHEMBL521658', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583411, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8170893, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Oc1cccc(c1)c2nc([nH]c2c3ccncc3)c4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909413', 'parent_molecule_chembl_id': 'CHEMBL304624', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '50.84', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583325, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50.84', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8171090, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN1CCN(CCCNc2nc3ccc(Oc4ccc(NC(=O)Nc5cc(ccc5F)C(F)(F)F)cc4)cc3[nH]2)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909372', 'parent_molecule_chembl_id': 'CHEMBL1888322', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '15.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583556, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '15.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8171314, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2nccc(Nc3ccc4c(C)n[nH]c4c3)n2)cc(OC)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL479079', 'parent_molecule_chembl_id': 'CHEMBL479079', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '18.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583514, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '18.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8171531, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCn1c(nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc12)c6nonc6N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909363', 'parent_molecule_chembl_id': 'CHEMBL220241', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583399, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8171672, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(cc1Nc3nc(Nc4ccsc4C(=O)N)c5cc[nH]c5n3)N(CCC2(C)C)C(=O)CN(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL463931', 'parent_molecule_chembl_id': 'CHEMBL463931', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583388, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8172049, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4cccc(F)c4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL69757', 'parent_molecule_chembl_id': 'CHEMBL69757', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.52', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583613, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.52', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8172181, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2ccc(F)cc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL426800', 'parent_molecule_chembl_id': 'CHEMBL426800', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583586, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8172405, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccc(N\\C=C\\3/C(=O)Nc4ccccc34)cc2N1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794057', 'parent_molecule_chembl_id': 'CHEMBL1794057', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583442, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8172533, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(NC(=O)N1)c2ccc(F)cc2)C(=O)Nc3ccc4[nH]ncc4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL384073', 'parent_molecule_chembl_id': 'CHEMBL384073', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '19.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583381, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '19.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8172899, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc2c(c3ccnc(NCCCO)n3)c(nn2c1)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909404', 'parent_molecule_chembl_id': 'CHEMBL1909404', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.14', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583508, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8173035, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1cccc(c1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL407113', 'parent_molecule_chembl_id': 'CHEMBL407113', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583350, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8173424, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL306865', 'parent_molecule_chembl_id': 'CHEMBL306865', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '47.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583585, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '47.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8173565, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)Nc1ccc(cc1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL102936', 'parent_molecule_chembl_id': 'CHEMBL102936', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583352, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8173789, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Oc1c(Br)cc(C=C2C(=O)Nc3ccc(cc23)c4cccnc4)cc1Br', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794050', 'parent_molecule_chembl_id': 'CHEMBL1851668', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583465, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8173876, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(cc23)C(=O)NCCc4c[nH]cn4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272028', 'parent_molecule_chembl_id': 'CHEMBL272028', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583448, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8174232, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)c1cncc(\\C=C\\c2c(C)cc(O)cc2C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL220243', 'parent_molecule_chembl_id': 'CHEMBL220243', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583459, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8174380, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2occ(c3ccc(NC(=O)Nc4cc(cc(c4)C(F)(F)F)C(F)(F)F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL396107', 'parent_molecule_chembl_id': 'CHEMBL396107', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '48.88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583592, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '48.88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8174604, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(NCC1CC1)c2ccc(cc2)c3cccc(c3)C(=O)NC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL479038', 'parent_molecule_chembl_id': 'CHEMBL479038', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583602, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8174726, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc2\\C(=N\\Nc3ccc(cc3)S(=O)(=O)N)\\C(=O)Nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909398', 'parent_molecule_chembl_id': 'CHEMBL1909398', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583439, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8175093, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(ncc(OCC3CCNCC3)c12)C#CC(C)(C)O)c4nonc4N.OC(=O)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794065', 'parent_molecule_chembl_id': 'CHEMBL521658', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583411, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8175229, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)c1ccc(Nc2nccc(n2)c3cnn4ncccc34)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL359963', 'parent_molecule_chembl_id': 'CHEMBL359963', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583599, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8175453, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)c1ccc(Nc2nccc(n2)c3cnn4ncccc34)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL359963', 'parent_molecule_chembl_id': 'CHEMBL359963', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583599, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8175485, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccccc2/C/1=C/Nc3ccc(cc3)n4cncn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794056', 'parent_molecule_chembl_id': 'CHEMBL1794056', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583450, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8175709, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccccc2/C/1=C/Nc3ccc(cc3)n4cncn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794056', 'parent_molecule_chembl_id': 'CHEMBL1794056', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583450, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8175872, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(c1ccc2c(C)nn(C)c2c1)c3ccnc(Nc4cccc(c4)S(=O)(=O)N)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794073', 'parent_molecule_chembl_id': 'CHEMBL476571', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '30.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583569, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '30.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8176025, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2c(cc1Nc3nc(Nc4ccsc4C(=O)N)c5cc[nH]c5n3)N(CCC2(C)C)C(=O)CN(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL463931', 'parent_molecule_chembl_id': 'CHEMBL463931', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583388, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8176249, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NCc1ccc(cc1)n2c(nc3cnccc23)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188268', 'parent_molecule_chembl_id': 'CHEMBL188268', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583355, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8176398, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4cccc(F)c4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL69757', 'parent_molecule_chembl_id': 'CHEMBL69757', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '52.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583613, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '52.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8176754, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccc(N\\C=C\\3/C(=O)Nc4ccccc34)cc2N1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794057', 'parent_molecule_chembl_id': 'CHEMBL1794057', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '19.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583442, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '19.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8176884, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(Cn1ccnc1)Oc2ccc(cc2)c3cc(ccn3)c4c[nH]nc4c5ccccn5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL208437', 'parent_molecule_chembl_id': 'CHEMBL208437', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583563, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8177108, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(Cn1ccnc1)Oc2ccc(cc2)c3cc(ccn3)c4c[nH]nc4c5ccccn5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL208437', 'parent_molecule_chembl_id': 'CHEMBL208437', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '56.36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583563, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '56.36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8177250, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1cc(O)cc(C)c1\\C=C\\c2cncc(c2)c3nn[nH]n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909352', 'parent_molecule_chembl_id': 'CHEMBL218791', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '19.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583472, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '19.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8177388, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1cccc(c1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL407113', 'parent_molecule_chembl_id': 'CHEMBL407113', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583350, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8177612, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2[nH]c3c4[nH]c5ccc(OC)cc5c4c6C(=O)NC(=O)c6c3c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1956068', 'parent_molecule_chembl_id': 'CHEMBL1956068', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583444, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8177776, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccncc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL306865', 'parent_molecule_chembl_id': 'CHEMBL306865', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '82.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583585, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '82.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8178140, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Oc1c(Br)cc(C=C2C(=O)Nc3ccc(cc23)c4cccnc4)cc1Br', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794050', 'parent_molecule_chembl_id': 'CHEMBL1851668', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583465, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8178228, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(cc23)C(=O)NCCc4c[nH]cn4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272028', 'parent_molecule_chembl_id': 'CHEMBL272028', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583448, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8178452, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C(=O)O[C@H]1CN[C@@H](C1)C#Cc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517123', 'parent_molecule_chembl_id': 'CHEMBL517123', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583383, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8178579, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)c1cncc(\\C=C\\c2c(C)cc(O)cc2C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL220243', 'parent_molecule_chembl_id': 'CHEMBL220243', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '57.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583459, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '57.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8178952, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(NCC1CC1)c2ccc(cc2)c3cccc(c3)C(=O)NC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL479038', 'parent_molecule_chembl_id': 'CHEMBL479038', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583602, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8179075, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCNC(=O)O[C@H]1CN[C@@H](C1)C#Cc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL512076', 'parent_molecule_chembl_id': 'CHEMBL512076', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583384, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8179299, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCNC(=O)O[C@H]1CN[C@@H](C1)C#Cc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL512076', 'parent_molecule_chembl_id': 'CHEMBL512076', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.21', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583384, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.21', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8179443, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(cc23)C(=O)NCc4ccncc4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272165', 'parent_molecule_chembl_id': 'CHEMBL272165', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583447, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8179804, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCCN(CCS(=O)(=O)C)Cc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909394', 'parent_molecule_chembl_id': 'CHEMBL212251', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583520, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8180061, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN1CCC(CC1)C(=O)Nc2n[nH]c3nnc(cc23)c4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909344', 'parent_molecule_chembl_id': 'CHEMBL406125', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583331, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8180215, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(c1ccc2c(C)nn(C)c2c1)c3ccnc(Nc4cccc(c4)S(=O)(=O)N)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794073', 'parent_molecule_chembl_id': 'CHEMBL476571', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '74.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583569, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '74.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8180595, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NCc1ccc(cc1)n2c(nc3cnccc23)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188268', 'parent_molecule_chembl_id': 'CHEMBL188268', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583355, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8180743, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1ccc2NC(=O)\\C(=C/Nc3ccc(cc3)S(=O)(=O)N)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272414', 'parent_molecule_chembl_id': 'CHEMBL272414', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583462, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8181100, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(O)cc1Nc2ccnc3ccc(cc23)S(=O)(=O)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL237347', 'parent_molecule_chembl_id': 'CHEMBL237347', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '80.76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583486, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '80.76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8181455, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C\\C(=C/1\\C(=O)Nc2ccccc12)\\Nc3ccc(cc3)S(=O)(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL405042', 'parent_molecule_chembl_id': 'CHEMBL405042', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.23', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583454, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.23', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8181595, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1cc(O)cc(C)c1\\C=C\\c2cncc(c2)c3nn[nH]n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909352', 'parent_molecule_chembl_id': 'CHEMBL218791', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '68.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583472, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '68.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8181958, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2[nH]c3c4[nH]c5ccc(OC)cc5c4c6C(=O)NC(=O)c6c3c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1956068', 'parent_molecule_chembl_id': 'CHEMBL1956068', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583444, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8182121, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(c2ccc(F)cc2)c(s1)c3ccc4ncccc4n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL361237', 'parent_molecule_chembl_id': 'CHEMBL361237', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583587, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8182485, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2nccc(n2)c3c(nn4ncccc34)c5ccc(cc5)C(F)(F)F)cc1F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188784', 'parent_molecule_chembl_id': 'CHEMBL188784', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583625, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8182801, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)C(=O)O[C@H]1CN[C@@H](C1)C#Cc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517123', 'parent_molecule_chembl_id': 'CHEMBL517123', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.24', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583383, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.24', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8182923, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccc(F)cc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL65884', 'parent_molecule_chembl_id': 'CHEMBL65884', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.51', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583614, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.51', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8183147, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccc(F)cc4)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL65884', 'parent_molecule_chembl_id': 'CHEMBL65884', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '57.91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583614, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '57.91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8183296, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3cccc(OC)c3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL179311', 'parent_molecule_chembl_id': 'CHEMBL179311', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '27.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583507, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '27.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8183649, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc6OCCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185939', 'parent_molecule_chembl_id': 'CHEMBL185939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583624, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8183791, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(cc23)C(=O)NCc4ccncc4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272165', 'parent_molecule_chembl_id': 'CHEMBL272165', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583447, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8184151, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CCCN(CCS(=O)(=O)C)Cc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909394', 'parent_molecule_chembl_id': 'CHEMBL212251', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.25', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583520, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.25', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8184417, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN1CCC(CC1)C(=O)Nc2n[nH]c3nnc(cc23)c4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909344', 'parent_molecule_chembl_id': 'CHEMBL406125', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583331, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8184564, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)c5ccc[nH]5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909415', 'parent_molecule_chembl_id': 'CHEMBL473436', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.02', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583551, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.02', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8184788, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)c5ccc[nH]5)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909415', 'parent_molecule_chembl_id': 'CHEMBL473436', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583551, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8184945, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc6OCCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365297', 'parent_molecule_chembl_id': 'CHEMBL365297', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583619, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8185094, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1ccc2NC(=O)\\C(=C/Nc3ccc(cc3)S(=O)(=O)N)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272414', 'parent_molecule_chembl_id': 'CHEMBL272414', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.52', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583462, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.52', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8185318, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)NCc1cccc(c1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL207247', 'parent_molecule_chembl_id': 'CHEMBL207247', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583603, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8185449, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(O)cc1Nc2ccnc3ccc(cc23)S(=O)(=O)C', 'data_validity_comment': 'No data provided for value, units or activity_comment, needs further investigation', 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL237347', 'parent_molecule_chembl_id': 'CHEMBL237347', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': None, 'qudt_units': None, 'record_id': 1583486, 'src_id': 16, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 8185804, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C\\C(=C/1\\C(=O)Nc2ccccc12)\\Nc3ccc(cc3)S(=O)(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL405042', 'parent_molecule_chembl_id': 'CHEMBL405042', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583454, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8185943, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1n[nH]c2cc(ccc12)c3ccccc3)C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL405021', 'parent_molecule_chembl_id': 'CHEMBL405021', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583339, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8186167, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1n[nH]c2cc(ccc12)c3ccccc3)C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL405021', 'parent_molecule_chembl_id': 'CHEMBL405021', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '31.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583339, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '31.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8186308, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc(F)c(F)c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL427159', 'parent_molecule_chembl_id': 'CHEMBL427159', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.7', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583623, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.7', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8186472, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(c2ccc(F)cc2)c(s1)c3ccc4ncccc4n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL361237', 'parent_molecule_chembl_id': 'CHEMBL361237', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '20.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583587, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '20.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8186696, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)C2=C(N3CCc4ccccc34)C(=O)NC2=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL347580', 'parent_molecule_chembl_id': 'CHEMBL347580', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583313, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8186835, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2nccc(n2)c3c(nn4ncccc34)c5ccc(cc5)C(F)(F)F)cc1F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188784', 'parent_molecule_chembl_id': 'CHEMBL188784', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.03', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583625, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.03', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8187157, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(O)cc(C)c1\\C=C\\c2cncc(c2)C(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218088', 'parent_molecule_chembl_id': 'CHEMBL218088', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583468, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8187505, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2c(cnn2n1)c3ccnc(Nc4cccc(OC(F)(F)F)c4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365248', 'parent_molecule_chembl_id': 'CHEMBL365248', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583607, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8187653, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3cccc(OC)c3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL179311', 'parent_molecule_chembl_id': 'CHEMBL179311', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '72.59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583507, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '72.59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8188006, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc6OCCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185939', 'parent_molecule_chembl_id': 'CHEMBL185939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.47', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583624, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.47', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8188149, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(Cl)cc23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL270054', 'parent_molecule_chembl_id': 'CHEMBL270054', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583437, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8188373, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(N\\N=C\\2/C(=O)Nc3ccc(Cl)cc23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL270054', 'parent_molecule_chembl_id': 'CHEMBL270054', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583437, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8188508, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccc(cc4)S(=O)(=O)C)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL66292', 'parent_molecule_chembl_id': 'CHEMBL66292', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '45.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583609, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '45.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8188782, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2oc(cc2)c3cc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4s3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL475761', 'parent_molecule_chembl_id': 'CHEMBL475761', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.53', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583584, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.53', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8189154, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(\\C=N\\Nc2ncnc3c2cnn3C(C)C)ccc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL63728', 'parent_molecule_chembl_id': 'CHEMBL63728', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '16.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583533, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '16.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8189310, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc6OCCOc6c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365297', 'parent_molecule_chembl_id': 'CHEMBL365297', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '56.14', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583619, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '56.14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8189683, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)NCc1cccc(c1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL207247', 'parent_molecule_chembl_id': 'CHEMBL207247', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583603, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8189815, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCCCCOc1ccc2ncnc(Nc3cccc(c3)C#C)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517907', 'parent_molecule_chembl_id': 'CHEMBL517907', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583541, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8190039, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCCCCOc1ccc2ncnc(Nc3cccc(c3)C#C)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL517907', 'parent_molecule_chembl_id': 'CHEMBL517907', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '14.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583541, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '14.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8190171, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccccc1c2cc(\\C=C\\3/C(=O)Nc4ncc(Br)cc34)cc(Br)c2O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL176857', 'parent_molecule_chembl_id': 'CHEMBL176857', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583473, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8190535, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1cc(cc(c1N)c2ccccc2)c3ccncc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL230911', 'parent_molecule_chembl_id': 'CHEMBL230911', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583420, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8190672, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccc(F)c(F)c5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL427159', 'parent_molecule_chembl_id': 'CHEMBL427159', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583623, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8191060, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)C2=C(N3CCc4ccccc34)C(=O)NC2=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL347580', 'parent_molecule_chembl_id': 'CHEMBL347580', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583313, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8191198, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(C)CCNC(=O)Nc1ccc(cc1)N(C)c2ccnc(Nc3ccc(CS(=O)(=O)C)cc3)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909362', 'parent_molecule_chembl_id': 'CHEMBL187930', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583266, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8191422, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(C)CCNC(=O)Nc1ccc(cc1)N(C)c2ccnc(Nc3ccc(CS(=O)(=O)C)cc3)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909362', 'parent_molecule_chembl_id': 'CHEMBL187930', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '16.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583266, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '16.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8191518, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(O)cc(C)c1\\C=C\\c2cncc(c2)C(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218088', 'parent_molecule_chembl_id': 'CHEMBL218088', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '59.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583468, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '59.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8191864, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2c(cnn2n1)c3ccnc(Nc4cccc(OC(F)(F)F)c4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365248', 'parent_molecule_chembl_id': 'CHEMBL365248', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '19.06', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583607, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '19.06', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8192013, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1cccc(CC)c1\\C=C\\c2cncc(c2)C(=O)NC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL385426', 'parent_molecule_chembl_id': 'CHEMBL385426', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583478, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8192237, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1cccc(CC)c1\\C=C\\c2cncc(c2)C(=O)NC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL385426', 'parent_molecule_chembl_id': 'CHEMBL385426', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583478, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8192366, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(CNC(=O)c2ccc(cc2)c3cc(ccc3C)c4oc(C)nn4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL269985', 'parent_molecule_chembl_id': 'CHEMBL269985', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583557, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8192734, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cncc(\\C=C\\c2ccccc2C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218969', 'parent_molecule_chembl_id': 'CHEMBL218969', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583476, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8192870, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccc(cc4)S(=O)(=O)C)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL66292', 'parent_molecule_chembl_id': 'CHEMBL66292', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '61.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583609, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '61.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8193142, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2oc(cc2)c3cc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4s3)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL475761', 'parent_molecule_chembl_id': 'CHEMBL475761', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '10.72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583584, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '10.72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8193511, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(\\C=N\\Nc2ncnc3c2cnn3C(C)C)ccc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL63728', 'parent_molecule_chembl_id': 'CHEMBL63728', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '68.53', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583533, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '68.53', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8193668, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1cccc(N\\C=C\\2/C(=O)Nc3ccccc23)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794059', 'parent_molecule_chembl_id': 'CHEMBL1794059', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583432, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8193892, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1cccc(N\\C=C\\2/C(=O)Nc3ccccc23)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794059', 'parent_molecule_chembl_id': 'CHEMBL1794059', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '13.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583432, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8194041, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nccc12)N3CCCC3)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL187985', 'parent_molecule_chembl_id': 'CHEMBL187985', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583354, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8194396, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1cc2ncnc(Nc3ccc(C)c(O)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909357', 'parent_molecule_chembl_id': 'CHEMBL478442', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '15.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583461, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '15.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8194527, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccccc1c2cc(\\C=C\\3/C(=O)Nc4ncc(Br)cc34)cc(Br)c2O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL176857', 'parent_molecule_chembl_id': 'CHEMBL176857', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '15.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583473, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '15.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8194894, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1cc(cc(c1N)c2ccccc2)c3ccncc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL230911', 'parent_molecule_chembl_id': 'CHEMBL230911', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '54.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583420, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '54.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8195027, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)n2cnc(c3ccc(F)cc3)c2c4ccnc(NCCO)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL330422', 'parent_molecule_chembl_id': 'CHEMBL330422', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583289, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8195251, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCC(CC1)n2cnc(c3ccc(F)cc3)c2c4ccnc(NCCO)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL330422', 'parent_molecule_chembl_id': 'CHEMBL330422', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583289, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8195415, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Cl)cc(C=C2C(=O)Nc3ccc(cc23)C(=O)c4occc4)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1789963', 'parent_molecule_chembl_id': 'CHEMBL1789963', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.9', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583458, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8195778, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCc1ccc(cc1)c2nc(c3ccccn3)c([nH]2)c4ccc5OCOc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL267228', 'parent_molecule_chembl_id': 'CHEMBL267228', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583320, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8195876, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(N=C(N1)c2ccc(nc2)C(F)(F)F)c3ccc(F)cc3)C(=O)Nc4ccc5[nH]ncc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL485598', 'parent_molecule_chembl_id': 'CHEMBL485598', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583406, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8196100, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(N=C(N1)c2ccc(nc2)C(F)(F)F)c3ccc(F)cc3)C(=O)Nc4ccc5[nH]ncc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL485598', 'parent_molecule_chembl_id': 'CHEMBL485598', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583406, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8196217, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.C(c1ccccc1)c2nc3ccc(Nc4ncnc5ccccc45)cc3[nH]2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909379', 'parent_molecule_chembl_id': 'CHEMBL32464', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583366, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8196591, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2c(c3ccnc(Nc4ccccc4)n3)c(nn2n1)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189459', 'parent_molecule_chembl_id': 'CHEMBL189459', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583270, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8196719, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(CNC(=O)c2ccc(cc2)c3cc(ccc3C)c4oc(C)nn4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL269985', 'parent_molecule_chembl_id': 'CHEMBL269985', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583557, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8197084, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNC(=O)c1cncc(\\C=C\\c2ccccc2C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL218969', 'parent_molecule_chembl_id': 'CHEMBL218969', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '16.14', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583476, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '16.14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8197221, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1ccc2c(cnn2n1)c3ccnc(Nc4cc(OC)cc(c4)C(F)(F)F)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188426', 'parent_molecule_chembl_id': 'CHEMBL188426', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583604, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8197445, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1ccc2c(cnn2n1)c3ccnc(Nc4cc(OC)cc(c4)C(F)(F)F)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188426', 'parent_molecule_chembl_id': 'CHEMBL188426', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.53', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583604, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.53', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8197496, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1cc(cc(c1N)c2ccncc2)c3ccc(F)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL231623', 'parent_molecule_chembl_id': 'CHEMBL231623', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.26', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583419, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.26', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8197720, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1cc(cc(c1N)c2ccncc2)c3ccc(F)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL231623', 'parent_molecule_chembl_id': 'CHEMBL231623', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583419, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8197860, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4Cl)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514162', 'parent_molecule_chembl_id': 'CHEMBL514162', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583274, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8198241, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1ccc(cc1)c2nc3SCCn3c2c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909406', 'parent_molecule_chembl_id': 'CHEMBL313417', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583362, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8198379, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1c(nc2c(nccc12)N3CCCC3)c4nonc4N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL187985', 'parent_molecule_chembl_id': 'CHEMBL187985', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583354, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8198733, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1cc2ncnc(Nc3ccc(C)c(O)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909357', 'parent_molecule_chembl_id': 'CHEMBL478442', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '65.15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583461, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '65.15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8198864, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(cc1)C2=C(N3CCc4ccccc34)C(=O)NC2=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL156524', 'parent_molecule_chembl_id': 'CHEMBL156524', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583309, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8199088, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(cc1)C2=C(N3CCc4ccccc34)C(=O)NC2=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL156524', 'parent_molecule_chembl_id': 'CHEMBL156524', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583309, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8199236, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1cc2c(Nc3ccc4nc(Cc5ccccc5)[nH]c4c3)ncnc2cn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL531804', 'parent_molecule_chembl_id': 'CHEMBL531804', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583451, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8199594, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncncc3C#Cc4ccccc4)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL379093', 'parent_molecule_chembl_id': 'CHEMBL379093', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.23', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583534, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.23', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8199757, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Cl)cc(C=C2C(=O)Nc3ccc(cc23)C(=O)c4occc4)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1789963', 'parent_molecule_chembl_id': 'CHEMBL1789963', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '15.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583458, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '15.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8200119, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCc1ccc(cc1)c2nc(c3ccccn3)c([nH]2)c4ccc5OCOc5c4', 'data_validity_comment': 'No data provided for value, units or activity_comment, needs further investigation', 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL267228', 'parent_molecule_chembl_id': 'CHEMBL267228', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': None, 'qudt_units': None, 'record_id': 1583320, 'src_id': 16, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 8200447, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccccc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189148', 'parent_molecule_chembl_id': 'CHEMBL189148', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583626, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8200562, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.C(c1ccccc1)c2nc3ccc(Nc4ncnc5ccccc45)cc3[nH]2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909379', 'parent_molecule_chembl_id': 'CHEMBL32464', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583366, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8200936, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc2c(c3ccnc(Nc4ccccc4)n3)c(nn2n1)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189459', 'parent_molecule_chembl_id': 'CHEMBL189459', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '34.06', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583270, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '34.06', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8201066, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4cccs4)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL480382', 'parent_molecule_chembl_id': 'CHEMBL480382', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.54', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583403, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.54', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8201290, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4cccs4)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL480382', 'parent_molecule_chembl_id': 'CHEMBL480382', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '18.45', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583403, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '18.45', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8201425, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(cc1)c2cc3ccncc3cc2OCc4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL483748', 'parent_molecule_chembl_id': 'CHEMBL483748', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.51', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583427, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.51', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8201782, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2cc(ccc2c1)c3c(nc(c4ccc(cc4C)[S+](C)[O-])n3C)c5ccncc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL237570', 'parent_molecule_chembl_id': 'CHEMBL237570', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583327, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8202061, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(c4)C(F)(F)F)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL215814', 'parent_molecule_chembl_id': 'CHEMBL215814', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583501, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8202201, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4Cl)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514162', 'parent_molecule_chembl_id': 'CHEMBL514162', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '21.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583274, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '21.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8202425, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Nc1nc(cs1)c2ccc3NC(=O)C(=Cc4cc(Br)c(O)c(Br)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794053', 'parent_molecule_chembl_id': 'CHEMBL1852697', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.45', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583460, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.45', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8202592, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1ccc(cc1)c2nc3SCCn3c2c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909406', 'parent_molecule_chembl_id': 'CHEMBL313417', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583362, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8202717, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2cc(ccn2)c3c[nH]nc3c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL381948', 'parent_molecule_chembl_id': 'CHEMBL381948', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.48', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583543, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.48', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8202941, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2cc(ccn2)c3c[nH]nc3c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL381948', 'parent_molecule_chembl_id': 'CHEMBL381948', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583543, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8203071, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)C(=C1Nc2ccccc2)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL346551', 'parent_molecule_chembl_id': 'CHEMBL346551', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583361, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8203426, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(c1ccc2c(C)n(C)nc2c1)c3ccnc(Nc4cccc(c4)S(=O)(=O)N)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909359', 'parent_molecule_chembl_id': 'CHEMBL514838', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '19.51', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583572, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '19.51', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8203572, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1cc2c(Nc3ccc4nc(Cc5ccccc5)[nH]c4c3)ncnc2cn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL531804', 'parent_molecule_chembl_id': 'CHEMBL531804', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.06', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583451, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.06', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8203930, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cccc(COc2ccc(Nc3ncncc3C#Cc4ccccc4)cc2Cl)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL379093', 'parent_molecule_chembl_id': 'CHEMBL379093', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583534, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8204096, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(O)cc(C)c1\\C=C\\c2cncc(c2)C(=O)OC(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL374060', 'parent_molecule_chembl_id': 'CHEMBL374060', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583469, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8204320, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(O)cc(C)c1\\C=C\\c2cncc(c2)C(=O)OC(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL374060', 'parent_molecule_chembl_id': 'CHEMBL374060', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '36.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583469, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '36.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8204457, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1ccc(O)cc1Nc2ccnc3cc(ccc23)c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL581096', 'parent_molecule_chembl_id': 'CHEMBL395358', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '74.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583470, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '74.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8204786, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(cc1)c2nn3ncccc3c2c4ccnc(Nc5ccccc5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL189148', 'parent_molecule_chembl_id': 'CHEMBL189148', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '18.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583626, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '18.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8204901, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(\\C=N\\Nc2ncnc3[nH]ncc23)ccc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL66004', 'parent_molecule_chembl_id': 'CHEMBL66004', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '15.55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583505, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '15.55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8205125, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(\\C=N\\Nc2ncnc3[nH]ncc23)ccc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL66004', 'parent_molecule_chembl_id': 'CHEMBL66004', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '65.74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583505, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '65.74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8205274, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C1CN(CCO1)c2ccc3c(cnn3n2)c4ccnc(NC5CC5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL495771', 'parent_molecule_chembl_id': 'CHEMBL495771', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583560, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8205634, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1nccc2c1nc(c3nonc3N)n2CC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188240', 'parent_molecule_chembl_id': 'CHEMBL188240', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.48', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583345, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.48', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8205773, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(cc1)c2cc3ccncc3cc2OCc4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL483748', 'parent_molecule_chembl_id': 'CHEMBL483748', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.27', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583427, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.27', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8205997, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)CC2CC2)cc1c3ccc(cc3)C(=O)NCC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL516908', 'parent_molecule_chembl_id': 'CHEMBL516908', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583594, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8206129, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2cc(ccc2c1)c3c(nc(c4ccc(cc4C)[S+](C)[O-])n3C)c5ccncc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL237570', 'parent_molecule_chembl_id': 'CHEMBL237570', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583327, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8206405, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)CCNCc1oc(cc1)c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(c4)C(F)(F)F)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL215814', 'parent_molecule_chembl_id': 'CHEMBL215814', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583501, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8206772, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Nc1nc(cs1)c2ccc3NC(=O)C(=Cc4cc(Br)c(O)c(Br)c4)c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1794053', 'parent_molecule_chembl_id': 'CHEMBL1852697', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583460, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8206952, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCCn1c(nc2cnccc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191105', 'parent_molecule_chembl_id': 'CHEMBL191105', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583357, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8207302, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(c2cccc(Cl)c2)c(s1)c3ccc4ncccc4n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365663', 'parent_molecule_chembl_id': 'CHEMBL365663', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583578, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8207432, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)C(=C1Nc2ccccc2)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL346551', 'parent_molecule_chembl_id': 'CHEMBL346551', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.54', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583361, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.54', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8207788, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.CN(c1ccc2c(C)n(C)nc2c1)c3ccnc(Nc4cccc(c4)S(=O)(=O)N)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909359', 'parent_molecule_chembl_id': 'CHEMBL514838', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '62.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583572, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '62.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8207933, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(CNc1nccc(n1)c2cnn3ncccc23)CN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL524901', 'parent_molecule_chembl_id': 'CHEMBL524901', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.25', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583546, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.25', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8208157, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(CNc1nccc(n1)c2cnn3ncccc23)CN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL524901', 'parent_molecule_chembl_id': 'CHEMBL524901', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583546, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8208289, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2cc(ccn2)c3c[nH]nc3c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL202891', 'parent_molecule_chembl_id': 'CHEMBL202891', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583540, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8208679, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(CC(=O)N1)c2ccc3ccccc3c2)C(=O)Nc4ccc5[nH]ncc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL441702', 'parent_molecule_chembl_id': 'CHEMBL441702', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583400, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8208812, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1ccc(O)cc1Nc2ccnc3cc(ccc23)c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL581096', 'parent_molecule_chembl_id': 'CHEMBL395358', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '95.72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583470, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '95.72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8209141, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3cccc(c3)c4ccccc4F)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL372474', 'parent_molecule_chembl_id': 'CHEMBL372474', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.9', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583539, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8209481, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(c2ccccn2)c(s1)c3ccc4ncccc4n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL181361', 'parent_molecule_chembl_id': 'CHEMBL181361', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583550, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8209631, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C1CN(CCO1)c2ccc3c(cnn3n2)c4ccnc(NC5CC5)n4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL495771', 'parent_molecule_chembl_id': 'CHEMBL495771', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583560, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8209855, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(cc1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103098', 'parent_molecule_chembl_id': 'CHEMBL103098', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '6.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583346, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8209991, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1nccc2c1nc(c3nonc3N)n2CC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188240', 'parent_molecule_chembl_id': 'CHEMBL188240', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '11.16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583345, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '11.16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8210356, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)CC2CC2)cc1c3ccc(cc3)C(=O)NCC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL516908', 'parent_molecule_chembl_id': 'CHEMBL516908', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.68', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583594, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.68', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8210492, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1CCC(CC(=O)Nc2n[nH]c3nc(c(Br)cc23)c4cccs4)CC1.OC(C(O)C(=O)O)C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2062290', 'parent_molecule_chembl_id': 'CHEMBL101747', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.08', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583348, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.08', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8210751, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1oc(nn1)c2ccc(C)c(c2)c3ccc(cc3)C(=O)NCc4ccc(Cl)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL402108', 'parent_molecule_chembl_id': 'CHEMBL402108', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583561, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8211119, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)c1sc(cc1OCc2ccccc2C(F)(F)F)n3cnc4cc(OC)c(OC)cc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL473420', 'parent_molecule_chembl_id': 'CHEMBL473420', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583370, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8211289, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCCn1c(nc2cnccc12)c3nonc3N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191105', 'parent_molecule_chembl_id': 'CHEMBL191105', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-5.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583357, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-5.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8211636, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(c2cccc(Cl)c2)c(s1)c3ccc4ncccc4n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL365663', 'parent_molecule_chembl_id': 'CHEMBL365663', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583578, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8211765, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(cc1)c2nc3[nH]nc(NC(=O)C4CC4)c3cc2Br', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL260417', 'parent_molecule_chembl_id': 'CHEMBL260417', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.68', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583336, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.68', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8211989, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(cc1)c2nc3[nH]nc(NC(=O)C4CC4)c3cc2Br', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL260417', 'parent_molecule_chembl_id': 'CHEMBL260417', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '25.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583336, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '25.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8212121, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1cccc(c1)c2cc3ccncc3cc2OCc4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL483747', 'parent_molecule_chembl_id': 'CHEMBL483747', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583430, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8212486, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL419903', 'parent_molecule_chembl_id': 'CHEMBL419903', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583342, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8212619, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2cc(ccn2)c3c[nH]nc3c4ccccn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL202891', 'parent_molecule_chembl_id': 'CHEMBL202891', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '35.59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583540, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '35.59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8212843, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1oc(nn1)c2cccc(c2)c3ccc(cc3)C(=O)NCC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL257113', 'parent_molecule_chembl_id': 'CHEMBL257113', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.81', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583564, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.81', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8213013, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(CC(=O)N1)c2ccc3ccccc3c2)C(=O)Nc4ccc5[nH]ncc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL441702', 'parent_molecule_chembl_id': 'CHEMBL441702', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583400, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8213142, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nonc1c2nc3cnccc3n2C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185962', 'parent_molecule_chembl_id': 'CHEMBL185962', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583344, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8213366, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nonc1c2nc3cnccc3n2C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185962', 'parent_molecule_chembl_id': 'CHEMBL185962', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583344, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8213470, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3cccc(c3)c4ccccc4F)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL372474', 'parent_molecule_chembl_id': 'CHEMBL372474', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '65.09', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583539, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '65.09', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8213807, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(c2ccccn2)c(s1)c3ccc4ncccc4n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL181361', 'parent_molecule_chembl_id': 'CHEMBL181361', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583550, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8214178, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(cc1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103098', 'parent_molecule_chembl_id': 'CHEMBL103098', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.09', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583346, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.09', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8214315, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(O[C@H](C)c4ccccc4Cl)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL222419', 'parent_molecule_chembl_id': 'CHEMBL222419', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583394, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8214673, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1ccc(Nc2ccnc(Nc3cccc(c3)C(=O)N)n2)cc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909381', 'parent_molecule_chembl_id': 'CHEMBL250322', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '50.75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583500, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50.75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8214825, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1CCC(CC(=O)Nc2n[nH]c3nc(c(Br)cc23)c4cccs4)CC1.OC(C(O)C(=O)O)C(=O)O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2062290', 'parent_molecule_chembl_id': 'CHEMBL101747', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583348, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8215076, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1oc(nn1)c2ccc(C)c(c2)c3ccc(cc3)C(=O)NCc4ccc(Cl)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL402108', 'parent_molecule_chembl_id': 'CHEMBL402108', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583561, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8215300, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)c2c(ncn2CCCN3CCOCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL274863', 'parent_molecule_chembl_id': 'CHEMBL274863', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583283, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8215453, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)c1sc(cc1OCc2ccccc2C(F)(F)F)n3cnc4cc(OC)c(OC)cc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL473420', 'parent_molecule_chembl_id': 'CHEMBL473420', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583370, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8215617, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(F)(F)F.Fc1ccc(F)c(Cn2ccc3cc(Nc4ncnc5cc(C#C[C@@H]6C[C@H](CN6)OC(=O)N7CCOCC7)sc45)ccc23)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909410', 'parent_molecule_chembl_id': 'CHEMBL1963561', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583398, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8215841, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)C(F)(F)F.Fc1ccc(F)c(Cn2ccc3cc(Nc4ncnc5cc(C#C[C@@H]6C[C@H](CN6)OC(=O)N7CCOCC7)sc45)ccc23)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909410', 'parent_molecule_chembl_id': 'CHEMBL1963561', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.47', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583398, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.47', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8215960, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2nc(Nc3ccc(F)cc3C(=O)NC[C@@H](O)CO)c4cc[nH]c4n2)N5CCN(CC5)C(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL450071', 'parent_molecule_chembl_id': 'CHEMBL450071', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-1.39', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583377, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-1.39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8216303, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1sc(cc1OCc2ccccc2Br)n3cnc4ccc(cc34)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL481510', 'parent_molecule_chembl_id': 'CHEMBL481510', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583275, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8216439, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1cccc(c1)c2cc3ccncc3cc2OCc4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL483747', 'parent_molecule_chembl_id': 'CHEMBL483747', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '15.18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583430, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '15.18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8216663, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc2\\C(=C\\3/C(=O)Nc4ccccc34)\\CCc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL175321', 'parent_molecule_chembl_id': 'CHEMBL175321', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.63', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583365, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.63', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8216801, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2ccc3c(NC(=O)C4CC4)n[nH]c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL419903', 'parent_molecule_chembl_id': 'CHEMBL419903', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '12.26', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583342, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '12.26', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8217159, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1oc(nn1)c2cccc(c2)c3ccc(cc3)C(=O)NCC4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL257113', 'parent_molecule_chembl_id': 'CHEMBL257113', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.01', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583564, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.01', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8217333, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.N(c1ccc(Oc2ccccc2)cc1)c3oc(cn3)c4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909341', 'parent_molecule_chembl_id': 'CHEMBL194117', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583529, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8217688, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4S(=O)(=O)C)c(C#N)s3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL373751', 'parent_molecule_chembl_id': 'CHEMBL373751', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583407, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8217789, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1cc(NC2=C(C(=O)NC2=O)c3ccc(Cl)cc3)ccc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL160876', 'parent_molecule_chembl_id': 'CHEMBL160876', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583312, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8218013, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1cc(NC2=C(C(=O)NC2=O)c3ccc(Cl)cc3)ccc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL160876', 'parent_molecule_chembl_id': 'CHEMBL160876', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583312, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8218128, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O.Cl.CN(C)CCOc1ccc(cc1)c2nc(c3ccncc3)c([nH]2)c4ccc5\\C(=N\\O)\\CCc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909414', 'parent_molecule_chembl_id': 'CHEMBL477989', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583324, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8218479, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccc(cc4)C(=O)NCCN(C)C)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909383', 'parent_molecule_chembl_id': 'CHEMBL67374', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '73.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583583, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '73.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8218622, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(O[C@H](C)c4ccccc4Cl)c(s3)C(=O)N)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL222419', 'parent_molecule_chembl_id': 'CHEMBL222419', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '37.22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583394, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '37.22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8218846, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1ccc(cc1)c2oc3ncnc(N)c3c2c4ccc(NC(=O)Nc5cc(ccc5F)C(F)(F)F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909396', 'parent_molecule_chembl_id': 'CHEMBL194911', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '13.57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583567, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13.57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8218977, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Cc1ccc(Nc2ccnc(Nc3cccc(c3)C(=O)N)n2)cc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909381', 'parent_molecule_chembl_id': 'CHEMBL250322', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '77.12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583500, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '77.12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8219137, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(CN1CCOCC1)Oc2ccc(cc2)c3cc(ccn3)c4c[nH]nc4c5ccccn5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL205158', 'parent_molecule_chembl_id': 'CHEMBL205158', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583555, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8219361, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(CN1CCOCC1)Oc2ccc(cc2)c3cc(ccn3)c4c[nH]nc4c5ccccn5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL205158', 'parent_molecule_chembl_id': 'CHEMBL205158', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '34.11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583555, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '34.11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8219611, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)c2c(ncn2CCCN3CCOCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL274863', 'parent_molecule_chembl_id': 'CHEMBL274863', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583283, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8219772, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2coc3ncnc(N)c23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL196022', 'parent_molecule_chembl_id': 'CHEMBL196022', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583530, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8220165, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(C(=O)Nc2sc3CCCCc3c2C#N)c4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL233002', 'parent_molecule_chembl_id': 'CHEMBL233002', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583360, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8220294, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2nc(Nc3ccc(F)cc3C(=O)NC[C@@H](O)CO)c4cc[nH]c4n2)N5CCN(CC5)C(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL450071', 'parent_molecule_chembl_id': 'CHEMBL450071', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583377, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8220632, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1sc(cc1OCc2ccccc2Br)n3cnc4ccc(cc34)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL481510', 'parent_molecule_chembl_id': 'CHEMBL481510', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583275, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8220994, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc2\\C(=C\\3/C(=O)Nc4ccccc34)\\CCc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL175321', 'parent_molecule_chembl_id': 'CHEMBL175321', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '9.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583365, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '9.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8221130, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nonc1c2nc3cnccc3n2C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185962', 'parent_molecule_chembl_id': 'CHEMBL185962', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583344, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8221487, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2nc(Nc3cccc(F)c3C(=O)O)c4cc[nH]c4n2)N5CCN(CC5)C(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514261', 'parent_molecule_chembl_id': 'CHEMBL514261', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.02', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583382, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.02', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8221652, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.N(c1ccc(Oc2ccccc2)cc1)c3oc(cn3)c4ccccc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909341', 'parent_molecule_chembl_id': 'CHEMBL194117', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '1.49', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583529, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.49', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8222007, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncn(c3cc(OCc4ccccc4S(=O)(=O)C)c(C#N)s3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL373751', 'parent_molecule_chembl_id': 'CHEMBL373751', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '17.96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583407, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '17.96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8222329, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCS(=O)(=O)c1ccc(OC)c(Nc2oc(cn2)c3cccc(c3)C(=O)C)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191705', 'parent_molecule_chembl_id': 'CHEMBL191705', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583519, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8222463, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O.Cl.CN(C)CCOc1ccc(cc1)c2nc(c3ccncc3)c([nH]2)c4ccc5\\C(=N\\O)\\CCc5c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909414', 'parent_molecule_chembl_id': 'CHEMBL477989', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '19.37', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583324, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '19.37', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8222687, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(Nc2oc(cn2)c3ccccc3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL194062', 'parent_molecule_chembl_id': 'CHEMBL194062', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '4.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583494, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8222805, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1cccc(c1)n2ncc3c(N\\N=C\\c4ccc(cc4)C(=O)NCCN(C)C)ncnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909383', 'parent_molecule_chembl_id': 'CHEMBL67374', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '82.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583583, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '82.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8223173, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.COc1ccc(cc1)c2oc3ncnc(N)c3c2c4ccc(NC(=O)Nc5cc(ccc5F)C(F)(F)F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909396', 'parent_molecule_chembl_id': 'CHEMBL194911', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '68.07', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583567, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '68.07', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8223302, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Fc1ccc(cc1NC(=O)Nc2ccc(Oc3ccc4[nH]c(NC(=O)c5ccccc5)nc4c3)cc2)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909374', 'parent_molecule_chembl_id': 'CHEMBL243917', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '25.05', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583562, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '25.05', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8223687, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261849', 'parent_molecule_chembl_id': 'CHEMBL261849', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.27', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583527, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.27', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8223937, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2cc(ccc2c1)c3c(nc(c4ccc(cc4C)S(=O)(=O)C)n3C)c5ccncc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL237571', 'parent_molecule_chembl_id': 'CHEMBL237571', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583328, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8224099, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2coc3ncnc(N)c23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL196022', 'parent_molecule_chembl_id': 'CHEMBL196022', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '8.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583530, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8224323, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccnc(c2)N3CCCC3)cc1c4ccc(cc4)C(=O)NCC5CC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL477182', 'parent_molecule_chembl_id': 'CHEMBL477182', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583568, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8224493, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(C(=O)Nc2sc3CCCCc3c2C#N)c4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL233002', 'parent_molecule_chembl_id': 'CHEMBL233002', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '7.43', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583360, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.43', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8224628, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1sc2N(CCCc2c1C#N)C(=O)C3CC3)c4cccc5ccccc45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL232601', 'parent_molecule_chembl_id': 'CHEMBL232601', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '2.9', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583273, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '2.9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8224852, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1sc2N(CCCc2c1C#N)C(=O)C3CC3)c4cccc5ccccc45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL232601', 'parent_molecule_chembl_id': 'CHEMBL232601', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583273, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8224966, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC1=C(C(CC(=O)N1)c2ccc(cc2)C(F)(F)F)C(=O)Nc3cc(Cl)c4[nH]ncc4c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL427058', 'parent_molecule_chembl_id': 'CHEMBL427058', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.63', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583410, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.63', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8225324, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NS(=O)(=O)c1ccc(Nc2cc(n[nH]2)c3cccc(O)c3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL103104', 'parent_molecule_chembl_id': 'CHEMBL103104', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583267, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8225462, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nonc1c2nc3cnccc3n2C4CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL185962', 'parent_molecule_chembl_id': 'CHEMBL185962', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-2.96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583344, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-2.96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8225686, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.C1Cc2nc(c3ccccn3)c(c4ccc5OCOc5c4)n2C1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909377', 'parent_molecule_chembl_id': 'CHEMBL268889', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '0.69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583317, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8225821, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(ccc1Nc2nc(Nc3cccc(F)c3C(=O)O)c4cc[nH]c4n2)N5CCN(CC5)C(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL514261', 'parent_molecule_chembl_id': 'CHEMBL514261', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '5.35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583382, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5.35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8225979, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Nc1nccc(n1)c2c(ncn2C3CCNCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909407', 'parent_molecule_chembl_id': 'CHEMBL274064', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '-0.73', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583284, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '-0.73', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8226203, 'assay_chembl_id': 'CHEMBL1962243', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cl.Nc1nccc(n1)c2c(ncn2C3CCNCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1909407', 'parent_molecule_chembl_id': 'CHEMBL274064', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '19.31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583284, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '19.31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 8226328, 'assay_chembl_id': 'CHEMBL1962242', 'assay_description': 'GSK_PKIS: ARG mean inhibition at 0.1 uM [Nanosyn]', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)C#Cc2cncnc2Nc3ccc(OCc4cccc(F)c4)c(Cl)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL1961873', 'document_journal': None, 'document_year': None, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL381604', 'parent_molecule_chembl_id': 'CHEMBL381604', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Inhibition', 'published_units': '%', 'published_value': '3.79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1583596, 'src_id': 16, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 10838551, 'assay_chembl_id': 'CHEMBL2014124', 'assay_description': 'Inhibition of ARG at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2c3ccnc(c3n(CCCCN)c2c1)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2010722', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2012, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2012574', 'parent_molecule_chembl_id': 'CHEMBL2012574', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '0', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1633209, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': 'Not Active', 'activity_id': 11022088, 'assay_chembl_id': 'CHEMBL2090280', 'assay_description': 'Inhibition of Arg at >1000 nM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C#Cc1cccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2086389', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2012, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2087361', 'parent_molecule_chembl_id': 'CHEMBL2087361', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1674287, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 12046240, 'assay_chembl_id': 'CHEMBL2157260', 'assay_description': 'Inhibition of Arg at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(O)C1CCN(Cc2ccc3nc(nc(N4CCOCC4)c3n2)c5c(F)ccc6[nH]ccc56)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2151019', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2012, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2152768', 'parent_molecule_chembl_id': 'CHEMBL2152768', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '0.3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1731548, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0.3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12074618, 'assay_chembl_id': 'CHEMBL2161015', 'assay_description': 'Inhibition of Arg at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CC(=O)N1CCC(CC1)c2ccc(NC(=O)c3nc(c[nH]3)C#N)c(c2)C4=CCCCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2157860', 'document_journal': 'J. Med. Chem.', 'document_year': 2011, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1908842', 'parent_molecule_chembl_id': 'CHEMBL1908842', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1733200, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12112606, 'assay_chembl_id': 'CHEMBL2173305', 'assay_description': 'Inhibition of ABL2 at 1 uM by 33P kinase hotspot assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc(Nc2ncc(F)c(Nc3ccccc3Cl)n2)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2169801', 'document_journal': 'J. Med. Chem.', 'document_year': 2012, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2170414', 'parent_molecule_chembl_id': 'CHEMBL2170414', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1740100, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12112607, 'assay_chembl_id': 'CHEMBL2173305', 'assay_description': 'Inhibition of ABL2 at 1 uM by 33P kinase hotspot assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(Sc4ccc(NC(=O)C5CC5)cc4)n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2169801', 'document_journal': 'J. Med. Chem.', 'document_year': 2012, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL572878', 'parent_molecule_chembl_id': 'CHEMBL572878', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1740350, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12173751, 'assay_chembl_id': 'CHEMBL2212089', 'assay_description': 'Inhibition of ABL2 assessed as residual activity at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1cc(ccn1)c2ccc(OCc3ccccc3)c(c2)C(=O)Nc4cccnc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2203081', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2012, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2204495', 'parent_molecule_chembl_id': 'CHEMBL2204495', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '100', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1757300, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '100', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12185167, 'assay_chembl_id': 'CHEMBL2216363', 'assay_description': 'Inhibition of ABL2', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)NS(=O)(=O)c1cncc(c1)c2ccn3nc(N)nc3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2203257', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2012, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2205766', 'parent_molecule_chembl_id': 'CHEMBL2205766', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'pIC50', 'published_units': None, 'published_value': '5', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1759115, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12207424, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCC(O)CCO\\N=C/1\\C(=C/2\\C(=O)Nc3ccccc23)\\Nc4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1802727', 'parent_molecule_chembl_id': 'CHEMBL1802727', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '45', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763564, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '45', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207425, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N\\C(=C(\\C#N)/c1cccc(c1)C(O)c2ccncc2)\\SC3CC=CC=C3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218939', 'parent_molecule_chembl_id': 'CHEMBL2218939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '104', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763565, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '104', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207426, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL23327', 'parent_molecule_chembl_id': 'CHEMBL23327', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763566, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207427, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(Nc2nc(cs2)c3ccc(Cl)cc3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1076555', 'parent_molecule_chembl_id': 'CHEMBL1076555', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '101', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763567, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '101', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207428, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCCc1c([nH]c2nccnc12)c3ccc(OC)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL306498', 'parent_molecule_chembl_id': 'CHEMBL306498', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763568, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207429, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(Nc2ccc(cc2)S(=O)(=O)N)nn1C(=S)Nc3c(F)cccc3F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261720', 'parent_molecule_chembl_id': 'CHEMBL261720', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '-2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763569, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '-2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207430, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(CNc2nc(nc3c2ncn3C(C)C)N(CCO)CCO)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL80713', 'parent_molecule_chembl_id': 'CHEMBL80713', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '113', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763570, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '113', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207431, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(CNC(=O)Nc2ncc(s2)[N+](=O)[O-])cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL259850', 'parent_molecule_chembl_id': 'CHEMBL259850', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '115', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763571, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '115', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207432, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c2ccccc2c3N=Nc4cccc1c34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1725279', 'parent_molecule_chembl_id': 'CHEMBL1725279', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763572, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207433, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'ClC1=C(N2C(=O)CCC2=O)C(=O)c3ccccc3C1=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL404939', 'parent_molecule_chembl_id': 'CHEMBL404939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763573, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207434, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1cccc(c1)c2cc3c(Oc4cccc(O)c4)ncnc3[nH]2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL405759', 'parent_molecule_chembl_id': 'CHEMBL405759', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '-3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763574, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '-3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207435, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)[C@H](CO)Nc1nc(Nc2cc(N)cc(Cl)c2)c3ncn(C(C)C)c3n1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL286721', 'parent_molecule_chembl_id': 'CHEMBL286721', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763575, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207436, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1n[nH]c2nc3ccccc3nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL259389', 'parent_molecule_chembl_id': 'CHEMBL259389', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763576, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207437, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)C(=O)c1ccc(Nc2nc(OCC3CCCCC3)c4nc[nH]c4n2)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1802728', 'parent_molecule_chembl_id': 'CHEMBL1802728', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '52', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763577, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '52', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207438, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O\\N=C/1\\C(=C/2\\C(=O)Nc3cc(Br)ccc23)\\Nc4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL409450', 'parent_molecule_chembl_id': 'CHEMBL409450', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '16', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763578, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '16', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207439, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1nc2c3ccccc3C(=O)c4cccc1c24', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1802485', 'parent_molecule_chembl_id': 'CHEMBL1802485', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '102', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763579, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '102', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207440, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N\\C(=C(/C#N)\\c1ccccc1C(F)(F)F)\\Sc2ccc(N)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218940', 'parent_molecule_chembl_id': 'CHEMBL2218940', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763580, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207441, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1ccc(\\C=C\\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL104264', 'parent_molecule_chembl_id': 'CHEMBL104264', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763581, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207442, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1ccc2c3nc4ccccc4n3C(=O)c5cccc1c25', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1182777', 'parent_molecule_chembl_id': 'CHEMBL1182777', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763582, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207443, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(CN1CCCCC1)Oc2ccc(cc2)c3cnc4c(cnn4c3)c5ccncc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL478629', 'parent_molecule_chembl_id': 'CHEMBL478629', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763583, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207444, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc(cc1)c2nc(c3ccc4OCCOc4c3)c([nH]2)c5ccccn5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL410456', 'parent_molecule_chembl_id': 'CHEMBL410456', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '113', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763584, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '113', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207445, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)c1nn(c2N=C(Cc3ccc(OCCO)cc3)NC(=O)c12)c4c(Cl)cccc4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL258721', 'parent_molecule_chembl_id': 'CHEMBL258721', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763585, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207446, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)O\\N=C\\1/C(=C\\2/C(=O)Nc3cc(Br)ccc23)/Nc4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218941', 'parent_molecule_chembl_id': 'CHEMBL2218941', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763586, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207447, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N#C\\C(=C/1\\Nc2ccccc2S1)\\c3ccnc(NCCc4cccnc4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191384', 'parent_molecule_chembl_id': 'CHEMBL191384', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763587, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207448, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2[nH]nc(Nc3ccc(F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1240885', 'parent_molecule_chembl_id': 'CHEMBL1240885', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '70', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763588, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '70', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207449, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1nc([nH]c1c2ccncc2)c3ccc(OC)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL278724', 'parent_molecule_chembl_id': 'CHEMBL278724', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '104', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763589, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '104', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207450, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2NC(=O)\\C(=C/c3cnc[nH]3)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL258805', 'parent_molecule_chembl_id': 'CHEMBL258805', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763590, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207451, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)\\C=C\\c1cc(Br)c(Br)c(Br)c1Br', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL270724', 'parent_molecule_chembl_id': 'CHEMBL270724', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763591, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207452, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N\\C(=N/[N+](=O)[O-])\\N\\N=C/c1oc(cc1)c2cccc(c2)[N+](=O)[O-]', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL221271', 'parent_molecule_chembl_id': 'CHEMBL221271', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763592, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207453, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCCCn1cc(C2=C(C(=O)NC2=O)c3cnccn3)c4cccnc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272629', 'parent_molecule_chembl_id': 'CHEMBL272629', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '101', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763593, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '101', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207454, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1sc2CCCCc2c1C#N)c3cccc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL233001', 'parent_molecule_chembl_id': 'CHEMBL233001', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '111', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763594, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '111', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207455, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ccc2ncnc(NCCc3ccc(Oc4ccccc4)cc3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL522502', 'parent_molecule_chembl_id': 'CHEMBL522502', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '104', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763595, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '104', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207456, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL278041', 'parent_molecule_chembl_id': 'CHEMBL278041', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763596, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207457, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2c(cnc3cnc(NCc4cccnc4)cc23)C#N)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL200381', 'parent_molecule_chembl_id': 'CHEMBL200381', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763597, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207458, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218926', 'parent_molecule_chembl_id': 'CHEMBL2218926', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '51', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763440, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '51', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207459, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)C(=C1c2c[nH]c3ccccc23)c4c[nH]c5ccccc45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL266487', 'parent_molecule_chembl_id': 'CHEMBL266487', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '25', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763441, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '25', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207460, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(Nc2cc(Nc3cccc(NC(=O)C4CC4)c3)ncn2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL387187', 'parent_molecule_chembl_id': 'CHEMBL387187', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '90', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763442, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '90', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207461, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(Cl)cc1NC(=O)Nc2cc(C)nc3ccccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL439259', 'parent_molecule_chembl_id': 'CHEMBL439259', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '114', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763443, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '114', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207462, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL53753', 'parent_molecule_chembl_id': 'CHEMBL53753', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763444, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207463, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2c1cnn2c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL65063', 'parent_molecule_chembl_id': 'CHEMBL65063', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763445, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207464, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cc(\\C=C\\2/C(=O)Nc3ccc(cc23)S(=O)(=O)N)c4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL104279', 'parent_molecule_chembl_id': 'CHEMBL104279', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '31', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763446, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '31', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207465, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL7917', 'parent_molecule_chembl_id': 'CHEMBL7917', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '10', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763447, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '10', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207466, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1nc2cc3nc(cnc3cc2n1C)c4cccs4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218927', 'parent_molecule_chembl_id': 'CHEMBL2218927', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763448, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207467, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cnc2cc3c(Nc4cccc(Br)c4)ncnc3cc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL174426', 'parent_molecule_chembl_id': 'CHEMBL174426', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '14', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763449, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207468, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC#CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL203644', 'parent_molecule_chembl_id': 'CHEMBL203644', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763450, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207469, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1cccc(c1)C(=O)Nc2nc3ccccc3n2CCN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL379787', 'parent_molecule_chembl_id': 'CHEMBL379787', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '103', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763451, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '103', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207470, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188762', 'parent_molecule_chembl_id': 'CHEMBL188762', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763452, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207471, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)n1nc(Cc2cccc3ccccc23)c4c(N)ncnc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL573578', 'parent_molecule_chembl_id': 'CHEMBL573578', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763453, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207472, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NCCNc1ncc(C(=O)N)c(Nc2cccc(c2)C(F)(F)F)n1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL471901', 'parent_molecule_chembl_id': 'CHEMBL471901', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '67', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763454, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207473, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccccc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL86943', 'parent_molecule_chembl_id': 'CHEMBL86943', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763455, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207474, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC[n+]1c(\\C=C\\N(C)c2ccccc2)n(c3ccccc3)c4ccc(cc14)c5nc6ccccc6s5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1186409', 'parent_molecule_chembl_id': 'CHEMBL1186409', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763456, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207475, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2c(c[n+](C)c3c2ccc4cc5OCOc5cc34)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL13045', 'parent_molecule_chembl_id': 'CHEMBL13045', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763457, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207476, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1OC)C(=O)Nc2sc3CCCCc3c2C(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL210833', 'parent_molecule_chembl_id': 'CHEMBL210833', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '101', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763458, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '101', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207477, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1nc2c3ccc(F)cc3c4C(=O)NC=Cc4c2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL21156', 'parent_molecule_chembl_id': 'CHEMBL21156', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '100', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763459, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '100', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207478, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4ccccc4[nH]3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL266325', 'parent_molecule_chembl_id': 'CHEMBL266325', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '116', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763460, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '116', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207479, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc4ccc(F)cc4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL7939', 'parent_molecule_chembl_id': 'CHEMBL7939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '58', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763461, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '58', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207480, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)\\C=C\\c1ccc2OCOc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL596380', 'parent_molecule_chembl_id': 'CHEMBL596380', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763462, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207481, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(NC(=O)c2ccccc2NCc3ccncc3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL101683', 'parent_molecule_chembl_id': 'CHEMBL101683', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '84', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763463, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '84', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207482, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1N=C(N)c2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c4ncnc1c24', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL331237', 'parent_molecule_chembl_id': 'CHEMBL331237', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763464, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207483, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL35820', 'parent_molecule_chembl_id': 'CHEMBL35820', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763465, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207484, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4cc(O)ccc4[nH]3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL377193', 'parent_molecule_chembl_id': 'CHEMBL377193', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763466, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207485, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(O)c(Br)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL473773', 'parent_molecule_chembl_id': 'CHEMBL473773', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '22', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763467, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '22', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207486, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(N3CCN(CC3)C(=O)Nc4ccc(Oc5ccccc5)cc4)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL102346', 'parent_molecule_chembl_id': 'CHEMBL102346', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '118', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763468, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '118', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207487, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)C(=C1Nc2ccccc2)c3cn(CCCn4ccnc4)c5ccccc35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL366266', 'parent_molecule_chembl_id': 'CHEMBL366266', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '60', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763469, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '60', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207488, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'c1ccc(nc1)c2n[nH]cc2c3ccnc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261454', 'parent_molecule_chembl_id': 'CHEMBL261454', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763470, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207489, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1289494', 'parent_molecule_chembl_id': 'CHEMBL1289494', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '-1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763471, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '-1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207490, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccccc2N1C3CCN(Cc4ccc(cc4)c5nc6cc7[nH]cnc7cc6nc5c8ccccc8)CC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL258844', 'parent_molecule_chembl_id': 'CHEMBL258844', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763472, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207491, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1C=C(Oc2c1ccc3ccccc23)N4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL104468', 'parent_molecule_chembl_id': 'CHEMBL104468', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '113', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763473, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '113', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207492, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261849', 'parent_molecule_chembl_id': 'CHEMBL261849', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '106', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763474, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '106', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207493, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL596674', 'parent_molecule_chembl_id': 'CHEMBL596674', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763475, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207494, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL120077', 'parent_molecule_chembl_id': 'CHEMBL120077', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763476, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207495, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\\C=C(/C)\\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\\C=C\\C=C\\C=C(/C)\\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL413', 'parent_molecule_chembl_id': 'CHEMBL413', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '118', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763477, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '118', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207496, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc(n1)c2[nH]c(nc2c3ccc4OCOc4c3)C(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL226838', 'parent_molecule_chembl_id': 'CHEMBL226838', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763478, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207497, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1ccc2NC(=O)\\C(=C\\c3cc4CCCCc4[nH]3)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218925', 'parent_molecule_chembl_id': 'CHEMBL2218925', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763479, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207498, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCCCN1c2ccccc2Oc3ccc(Cl)cc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1398474', 'parent_molecule_chembl_id': 'CHEMBL1398474', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '122', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763480, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '122', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207499, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)c1ccc(cc1O)N2CCOCC2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1317546', 'parent_molecule_chembl_id': 'CHEMBL1317546', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '102', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763481, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '102', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207500, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1c2ccccc2c3c4C(=O)NCc4c5c6ccccc6n(CCC#N)c5c13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL302449', 'parent_molecule_chembl_id': 'CHEMBL302449', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '69', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763482, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '69', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207501, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccc(cc2/C/1=C\\c3ccc[nH]3)c4cccnc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218929', 'parent_molecule_chembl_id': 'CHEMBL2218929', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '11', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763483, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207502, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccccc4C)cc3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218930', 'parent_molecule_chembl_id': 'CHEMBL2218930', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763484, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207503, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'c1ccc2c(c[nH]c2c1)c3ccncc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL380071', 'parent_molecule_chembl_id': 'CHEMBL380071', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763485, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207504, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(C=C(C#N)C#N)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL77456', 'parent_molecule_chembl_id': 'CHEMBL77456', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '114', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763486, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '114', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207505, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(C)c(\\C=C\\2/C(=O)Nc3ccccc23)[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL276711', 'parent_molecule_chembl_id': 'CHEMBL276711', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '81', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763487, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '81', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207506, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1c2ccccc2c3nc4nnnn4nc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL599894', 'parent_molecule_chembl_id': 'CHEMBL599894', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '113', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763488, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '113', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207507, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cccc(c1)c2nc(N3CCOCC3)c4oc5ncccc5c4n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL573339', 'parent_molecule_chembl_id': 'CHEMBL573339', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '102', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763489, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '102', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207508, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2c(c1)c(cn2CCCN(C)C)C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261491', 'parent_molecule_chembl_id': 'CHEMBL261491', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763490, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207509, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2c1c(cn2C3CCCC3)c4ccc(Oc5ccccc5)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL47940', 'parent_molecule_chembl_id': 'CHEMBL47940', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '21', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763491, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '21', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207510, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccc3ncsc3c2/C/1=C/c4c[nH]cn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL235641', 'parent_molecule_chembl_id': 'CHEMBL235641', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763492, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207511, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H]1CN(CCCN1S(=O)(=O)c2cccc3cncc(C)c23)C(=O)CN', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218931', 'parent_molecule_chembl_id': 'CHEMBL2218931', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763493, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207512, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(\\C=C(/C#N)\\C(=O)NCc2ccccc2)cc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL56543', 'parent_molecule_chembl_id': 'CHEMBL56543', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763494, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207513, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2cnc3c(cnn3c2)c4ccsc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL92461', 'parent_molecule_chembl_id': 'CHEMBL92461', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763495, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207514, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(NC(=O)c4ccccc4)cc3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL382590', 'parent_molecule_chembl_id': 'CHEMBL382590', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763496, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207515, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)C(=C2CCN(CCN3C(=S)Nc4ccccc4C3=O)CC2)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261131', 'parent_molecule_chembl_id': 'CHEMBL261131', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763497, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207516, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'o1c2ccccc2c3[nH]nc(c4ccccc4)c13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL406375', 'parent_molecule_chembl_id': 'CHEMBL406375', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763498, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207517, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1C=C(Oc2c1cccc2c3ccccc3)N4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL98350', 'parent_molecule_chembl_id': 'CHEMBL98350', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763499, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207518, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Cl)cc(\\C=C\\2/C(=O)Nc3ccc(Cl)cc23)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218932', 'parent_molecule_chembl_id': 'CHEMBL2218932', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763500, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207519, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35)N(C)C(=O)c9ccccc9', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL608533', 'parent_molecule_chembl_id': 'CHEMBL608533', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '45', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763501, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '45', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207520, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=C(C#N)C#N)\\C(=C\\c1ccc(O)cc1)\\C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL76589', 'parent_molecule_chembl_id': 'CHEMBL76589', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '107', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763502, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '107', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207521, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cc(ccc1C(=O)c2ccccc2)N3CCOCC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL478980', 'parent_molecule_chembl_id': 'CHEMBL478980', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763503, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207522, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1cccc(c1)c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL483847', 'parent_molecule_chembl_id': 'CHEMBL483847', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763504, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207523, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1ccc(\\C=C\\2/C(=O)Nc3ccccc23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL328710', 'parent_molecule_chembl_id': 'CHEMBL328710', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763505, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207524, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@H]1C[C@H](C)[C@@H](OC)C2=CC(=O)C=C(NC(=O)\\C(=C\\C=C\\[C@H](OC)[C@@H](OC(=O)N)\\C(=C\\[C@H](C)[C@H]1OC)\\C)\\C)C2=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL479533', 'parent_molecule_chembl_id': 'CHEMBL479533', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '105', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763506, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '105', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207525, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1C=C(Oc2c1cccc2c3ccccc3)N4CCNCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1363184', 'parent_molecule_chembl_id': 'CHEMBL1363184', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '101', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763507, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '101', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207526, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)\\C(=C/c2ccc3nccnc3c2)\\S1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218934', 'parent_molecule_chembl_id': 'CHEMBL2218934', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763508, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207527, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL97771', 'parent_molecule_chembl_id': 'CHEMBL97771', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763509, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207528, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc2ncc(nc2cc1C)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL7724', 'parent_molecule_chembl_id': 'CHEMBL7724', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '103', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763510, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '103', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207529, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL383899', 'parent_molecule_chembl_id': 'CHEMBL383899', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '44', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763511, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '44', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207530, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL7463', 'parent_molecule_chembl_id': 'CHEMBL7463', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763512, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207531, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL563845', 'parent_molecule_chembl_id': 'CHEMBL563845', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763513, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207532, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(CN1CCCC1)Oc2ccc(Nc3ncc(s3)c4ccccc4)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218935', 'parent_molecule_chembl_id': 'CHEMBL2218935', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763514, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207533, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(c1cccc(Cl)c1)S(=O)(=O)c2ccc3NC(=O)\\C(=C/C4=C(C)C(=C(C)C4)C(=O)N5CCN(C)CC5)\\c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218936', 'parent_molecule_chembl_id': 'CHEMBL2218936', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '61', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763515, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '61', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207534, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC1(F)Oc2ccc(\\C=C\\3/SC(=O)NC3=O)cc2O1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1231533', 'parent_molecule_chembl_id': 'CHEMBL1231533', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763516, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207535, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCNC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccc(Cl)cc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL13485', 'parent_molecule_chembl_id': 'CHEMBL13485', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '7', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763517, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '7', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207536, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncc(nc2cc1OC)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL71191', 'parent_molecule_chembl_id': 'CHEMBL71191', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '84', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763518, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '84', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207537, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL388978', 'parent_molecule_chembl_id': 'CHEMBL388978', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '-1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763519, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '-1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207538, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN([C@@H](Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)C(=O)N4CCN(CC4)c5ccccc5)S(=O)(=O)c6cccc7cnccc67', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL28324', 'parent_molecule_chembl_id': 'CHEMBL28324', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763520, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207539, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(Nc2ccc(cc2)S(=O)(=O)N)nn1C(=O)c3c(F)cccc3F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191003', 'parent_molecule_chembl_id': 'CHEMBL191003', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763521, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207540, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1ccc2c(c1)[nH]c3c4[nH]c5ccccc5c4c6C(=O)NC(=O)c6c23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL64758', 'parent_molecule_chembl_id': 'CHEMBL64758', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763522, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207541, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](N)[C@@H]1CC[C@H](CC1)C(=O)Nc2ccncc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL559147', 'parent_molecule_chembl_id': 'CHEMBL559147', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '100', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763523, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '100', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207542, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)S(=O)(=O)c1ccc2NC(=O)\\C(=C/c3cc4CCCCc4[nH]3)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL605003', 'parent_molecule_chembl_id': 'CHEMBL605003', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763524, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207543, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(NC(=O)CCCc2ccc(cc2)c3ccccc3F)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL235658', 'parent_molecule_chembl_id': 'CHEMBL235658', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763525, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207544, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CSc1nc(c2ccc(F)cc2)c([nH]1)c3ccnc(NC(C)c4ccccc4)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL111364', 'parent_molecule_chembl_id': 'CHEMBL111364', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763526, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207545, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[S+]([O-])c1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL10', 'parent_molecule_chembl_id': 'CHEMBL10', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763527, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207546, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1C=C(OC(=C1)c2cccc3Sc4ccccc4Sc23)N5CCOCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL222102', 'parent_molecule_chembl_id': 'CHEMBL222102', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '90', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763528, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '90', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207547, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1[nH]c2ccccc2c1c3[nH]c4ccccc4c3N=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL126077', 'parent_molecule_chembl_id': 'CHEMBL126077', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '28', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763529, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '28', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207548, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(OC)c2C(=S)c3ccccc3Nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1331734', 'parent_molecule_chembl_id': 'CHEMBL1331734', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '84', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763530, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '84', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207549, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1n[nH]c2nnc(cc12)c3c(nn4ccccc34)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL259551', 'parent_molecule_chembl_id': 'CHEMBL259551', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763531, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207550, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(Nc2nc(nc3ccccc23)c4ccccc4)n[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL359482', 'parent_molecule_chembl_id': 'CHEMBL359482', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763532, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207551, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1nc(NC(=O)Cc2cc(OC)ccc2OC)cc(N)c1C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL210618', 'parent_molecule_chembl_id': 'CHEMBL210618', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763533, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207552, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(c2ccc(F)cc2)c(nn1c3ccc(Cl)cc3)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL91730', 'parent_molecule_chembl_id': 'CHEMBL91730', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '53', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763534, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '53', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207553, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=S(=O)(N1CCCNCC1)c2cccc3cnccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL38380', 'parent_molecule_chembl_id': 'CHEMBL38380', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '80', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763535, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '80', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207554, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1cc(NC(=S)NC(NC(=O)C(c2ccccc2)c3ccccc3)C(Cl)(Cl)Cl)ccc1F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1221601', 'parent_molecule_chembl_id': 'CHEMBL1221601', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763536, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207555, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1)S(=O)(=O)\\C=C\\C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL403183', 'parent_molecule_chembl_id': 'CHEMBL403183', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763537, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207556, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC2=CC(=O)c3sc(C)nc3C2=O)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL290904', 'parent_molecule_chembl_id': 'CHEMBL290904', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763538, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207557, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1n[nH]c2nnc(cc12)c3c(nn4ccccc34)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218938', 'parent_molecule_chembl_id': 'CHEMBL2218938', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763539, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207558, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)c2c1c3c4ccccc4[nH]c3n5cncc25', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL413188', 'parent_molecule_chembl_id': 'CHEMBL413188', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '56', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763540, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '56', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207559, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)[C@@]1(O)C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL281948', 'parent_molecule_chembl_id': 'CHEMBL281948', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '35', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763541, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '35', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207560, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(C2=CC(=O)c3ccccc3O2)c1N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL35482', 'parent_molecule_chembl_id': 'CHEMBL35482', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763542, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207561, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)c2c1c3c4ccccc4n5C6CCC(O6)n7c8ccccc8c2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL304428', 'parent_molecule_chembl_id': 'CHEMBL304428', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763543, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207562, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1ccc2[nH]c3c(CC(=O)Nc4ccccc34)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL50894', 'parent_molecule_chembl_id': 'CHEMBL50894', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763544, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207563, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1cnc2c(NCc3ccccc3)nc(NCCCO)nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL83980', 'parent_molecule_chembl_id': 'CHEMBL83980', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763545, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207564, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1\\C(=C\\C(=O)C)\\Sc2ccc(OC)cc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL408982', 'parent_molecule_chembl_id': 'CHEMBL408982', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '81', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763546, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '81', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207565, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1c2ccccc2[n+]3ccc4c5ccccc5[nH]c4c13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL602937', 'parent_molecule_chembl_id': 'CHEMBL602937', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763547, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207566, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(OC)c(\\C=C\\2/C(=O)Nc3ccccc23)c(OC)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL404941', 'parent_molecule_chembl_id': 'CHEMBL404941', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763548, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207567, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1ccc2[nH]c3c(CC(=O)Nc4ccccc34)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL296586', 'parent_molecule_chembl_id': 'CHEMBL296586', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '45', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763549, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '45', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207568, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL17331', 'parent_molecule_chembl_id': 'CHEMBL17331', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763550, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207569, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1oc(c2ccncc2)c(n1)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL36450', 'parent_molecule_chembl_id': 'CHEMBL36450', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '45', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763551, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '45', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207570, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1ccc2[nH]c3c(CC(=O)Nc4ccc(CCC#N)cc34)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL260138', 'parent_molecule_chembl_id': 'CHEMBL260138', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '17', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763552, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '17', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207571, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1[nH]c2ccccc2c1\\C=C/3\\C(=O)Nc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261425', 'parent_molecule_chembl_id': 'CHEMBL261425', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '66', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763553, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '66', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207572, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc2[nH]c(nc2c1)c3ccc(Oc4ccc(Cl)cc4)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL179583', 'parent_molecule_chembl_id': 'CHEMBL179583', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763554, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207573, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1SC(=O)N(Cc2ccccc2)C1=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL284861', 'parent_molecule_chembl_id': 'CHEMBL284861', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '90', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763555, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '90', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207574, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL257167', 'parent_molecule_chembl_id': 'CHEMBL257167', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '19', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763556, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '19', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207575, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)S(=O)(=O)N(CCO)c2ccccc2CN(C)C\\C=C\\c3ccc(Cl)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL155333', 'parent_molecule_chembl_id': 'CHEMBL155333', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763557, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207576, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)c2c(ncn2C3CCNCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL274064', 'parent_molecule_chembl_id': 'CHEMBL274064', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '65', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763558, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '65', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207577, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2nc3SCCn3c2c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL313417', 'parent_molecule_chembl_id': 'CHEMBL313417', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763559, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207578, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCCc1c([nH]c2nccnc12)c3ccc(O)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL75680', 'parent_molecule_chembl_id': 'CHEMBL75680', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '60', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763560, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '60', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207579, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@@H]4CCCC[C@@H]4N)nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL367625', 'parent_molecule_chembl_id': 'CHEMBL367625', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763561, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207580, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1cnc2\\C(=N\\c3cccc(Cl)c3)\\N=C(NCCO)Nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL311228', 'parent_molecule_chembl_id': 'CHEMBL311228', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '10', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763562, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '10', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207581, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Ic1cccc(CSc2oc(nn2)c3ccncc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL288064', 'parent_molecule_chembl_id': 'CHEMBL288064', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763563, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207582, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCC(O)CCO\\N=C/1\\C(=C/2\\C(=O)Nc3ccccc23)\\Nc4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1802727', 'parent_molecule_chembl_id': 'CHEMBL1802727', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763564, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207583, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N\\C(=C(\\C#N)/c1cccc(c1)C(O)c2ccncc2)\\SC3CC=CC=C3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218939', 'parent_molecule_chembl_id': 'CHEMBL2218939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763565, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207584, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL23327', 'parent_molecule_chembl_id': 'CHEMBL23327', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763566, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207585, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(Nc2nc(cs2)c3ccc(Cl)cc3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1076555', 'parent_molecule_chembl_id': 'CHEMBL1076555', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763567, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207586, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCCc1c([nH]c2nccnc12)c3ccc(OC)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL306498', 'parent_molecule_chembl_id': 'CHEMBL306498', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '53', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763568, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '53', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207587, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(Nc2ccc(cc2)S(=O)(=O)N)nn1C(=S)Nc3c(F)cccc3F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261720', 'parent_molecule_chembl_id': 'CHEMBL261720', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '-2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763569, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '-2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207588, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(CNc2nc(nc3c2ncn3C(C)C)N(CCO)CCO)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL80713', 'parent_molecule_chembl_id': 'CHEMBL80713', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763570, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207589, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(CNC(=O)Nc2ncc(s2)[N+](=O)[O-])cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL259850', 'parent_molecule_chembl_id': 'CHEMBL259850', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763571, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207590, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c2ccccc2c3N=Nc4cccc1c34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1725279', 'parent_molecule_chembl_id': 'CHEMBL1725279', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '72', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763572, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '72', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207591, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'ClC1=C(N2C(=O)CCC2=O)C(=O)c3ccccc3C1=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL404939', 'parent_molecule_chembl_id': 'CHEMBL404939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763573, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207592, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1cccc(c1)c2cc3c(Oc4cccc(O)c4)ncnc3[nH]2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL405759', 'parent_molecule_chembl_id': 'CHEMBL405759', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '-2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763574, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '-2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207593, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)[C@H](CO)Nc1nc(Nc2cc(N)cc(Cl)c2)c3ncn(C(C)C)c3n1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL286721', 'parent_molecule_chembl_id': 'CHEMBL286721', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '8', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763575, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207594, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1n[nH]c2nc3ccccc3nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL259389', 'parent_molecule_chembl_id': 'CHEMBL259389', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763576, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207595, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)C(=O)c1ccc(Nc2nc(OCC3CCCCC3)c4nc[nH]c4n2)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1802728', 'parent_molecule_chembl_id': 'CHEMBL1802728', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '9', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763577, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207596, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O\\N=C/1\\C(=C/2\\C(=O)Nc3cc(Br)ccc23)\\Nc4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL409450', 'parent_molecule_chembl_id': 'CHEMBL409450', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763578, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207597, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1nc2c3ccccc3C(=O)c4cccc1c24', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1802485', 'parent_molecule_chembl_id': 'CHEMBL1802485', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763579, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207598, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N\\C(=C(/C#N)\\c1ccccc1C(F)(F)F)\\Sc2ccc(N)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218940', 'parent_molecule_chembl_id': 'CHEMBL2218940', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763580, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207599, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1ccc(\\C=C\\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL104264', 'parent_molecule_chembl_id': 'CHEMBL104264', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763581, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207600, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1ccc2c3nc4ccccc4n3C(=O)c5cccc1c25', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1182777', 'parent_molecule_chembl_id': 'CHEMBL1182777', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '74', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763582, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '74', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207601, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(CN1CCCCC1)Oc2ccc(cc2)c3cnc4c(cnn4c3)c5ccncc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL478629', 'parent_molecule_chembl_id': 'CHEMBL478629', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763583, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207602, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc(cc1)c2nc(c3ccc4OCCOc4c3)c([nH]2)c5ccccn5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL410456', 'parent_molecule_chembl_id': 'CHEMBL410456', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763584, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207603, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)c1nn(c2N=C(Cc3ccc(OCCO)cc3)NC(=O)c12)c4c(Cl)cccc4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL258721', 'parent_molecule_chembl_id': 'CHEMBL258721', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763585, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207604, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)O\\N=C\\1/C(=C\\2/C(=O)Nc3cc(Br)ccc23)/Nc4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218941', 'parent_molecule_chembl_id': 'CHEMBL2218941', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763586, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207605, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N#C\\C(=C/1\\Nc2ccccc2S1)\\c3ccnc(NCCc4cccnc4)n3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191384', 'parent_molecule_chembl_id': 'CHEMBL191384', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763587, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207606, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2[nH]nc(Nc3ccc(F)cc3)c12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1240885', 'parent_molecule_chembl_id': 'CHEMBL1240885', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '30', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763588, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '30', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207607, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1nc([nH]c1c2ccncc2)c3ccc(OC)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL278724', 'parent_molecule_chembl_id': 'CHEMBL278724', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763589, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207608, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2NC(=O)\\C(=C/c3cnc[nH]3)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL258805', 'parent_molecule_chembl_id': 'CHEMBL258805', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '47', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763590, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '47', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207609, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)\\C=C\\c1cc(Br)c(Br)c(Br)c1Br', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL270724', 'parent_molecule_chembl_id': 'CHEMBL270724', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '53', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763591, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '53', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207610, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N\\C(=N/[N+](=O)[O-])\\N\\N=C/c1oc(cc1)c2cccc(c2)[N+](=O)[O-]', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL221271', 'parent_molecule_chembl_id': 'CHEMBL221271', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763592, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207611, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OCCCn1cc(C2=C(C(=O)NC2=O)c3cnccn3)c4cccnc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL272629', 'parent_molecule_chembl_id': 'CHEMBL272629', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763593, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207612, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C(Nc1sc2CCCCc2c1C#N)c3cccc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL233001', 'parent_molecule_chembl_id': 'CHEMBL233001', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763594, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207613, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ccc2ncnc(NCCc3ccc(Oc4ccccc4)cc3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL522502', 'parent_molecule_chembl_id': 'CHEMBL522502', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763595, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207614, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL278041', 'parent_molecule_chembl_id': 'CHEMBL278041', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '41', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763596, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12207615, 'assay_chembl_id': 'CHEMBL2218947', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 10uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2c(cnc3cnc(NCc4cccnc4)cc23)C#N)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL200381', 'parent_molecule_chembl_id': 'CHEMBL200381', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '55', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763597, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '55', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249616, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218926', 'parent_molecule_chembl_id': 'CHEMBL2218926', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763440, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249617, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)C(=C1c2c[nH]c3ccccc23)c4c[nH]c5ccccc45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL266487', 'parent_molecule_chembl_id': 'CHEMBL266487', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '78', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763441, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '78', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249618, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(Nc2cc(Nc3cccc(NC(=O)C4CC4)c3)ncn2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL387187', 'parent_molecule_chembl_id': 'CHEMBL387187', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763442, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249619, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(Cl)cc1NC(=O)Nc2cc(C)nc3ccccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL439259', 'parent_molecule_chembl_id': 'CHEMBL439259', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763443, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249620, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL53753', 'parent_molecule_chembl_id': 'CHEMBL53753', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763444, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249621, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2c1cnn2c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL65063', 'parent_molecule_chembl_id': 'CHEMBL65063', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '103', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763445, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '103', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249622, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cc(\\C=C\\2/C(=O)Nc3ccc(cc23)S(=O)(=O)N)c4ccccc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL104279', 'parent_molecule_chembl_id': 'CHEMBL104279', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '57', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763446, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '57', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249623, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL7917', 'parent_molecule_chembl_id': 'CHEMBL7917', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '48', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763447, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '48', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249624, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1nc2cc3nc(cnc3cc2n1C)c4cccs4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218927', 'parent_molecule_chembl_id': 'CHEMBL2218927', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763448, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249625, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1cnc2cc3c(Nc4cccc(Br)c4)ncnc3cc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL174426', 'parent_molecule_chembl_id': 'CHEMBL174426', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '42', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763449, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '42', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249626, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC#CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cn1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL203644', 'parent_molecule_chembl_id': 'CHEMBL203644', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '118', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763450, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '118', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249627, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1cccc(c1)C(=O)Nc2nc3ccccc3n2CCN4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL379787', 'parent_molecule_chembl_id': 'CHEMBL379787', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '100', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763451, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '100', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249628, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL188762', 'parent_molecule_chembl_id': 'CHEMBL188762', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763452, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249629, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)n1nc(Cc2cccc3ccccc23)c4c(N)ncnc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL573578', 'parent_molecule_chembl_id': 'CHEMBL573578', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '68', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763453, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '68', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249630, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NCCNc1ncc(C(=O)N)c(Nc2cccc(c2)C(F)(F)F)n1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL471901', 'parent_molecule_chembl_id': 'CHEMBL471901', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763454, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249631, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccccc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL86943', 'parent_molecule_chembl_id': 'CHEMBL86943', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '101', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763455, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '101', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249632, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC[n+]1c(\\C=C\\N(C)c2ccccc2)n(c3ccccc3)c4ccc(cc14)c5nc6ccccc6s5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1186409', 'parent_molecule_chembl_id': 'CHEMBL1186409', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '112', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763456, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '112', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249633, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2c(c[n+](C)c3c2ccc4cc5OCOc5cc34)c1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL13045', 'parent_molecule_chembl_id': 'CHEMBL13045', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763457, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249634, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1OC)C(=O)Nc2sc3CCCCc3c2C(=O)N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL210833', 'parent_molecule_chembl_id': 'CHEMBL210833', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '126', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763458, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '126', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249635, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1nc2c3ccc(F)cc3c4C(=O)NC=Cc4c2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL21156', 'parent_molecule_chembl_id': 'CHEMBL21156', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '128', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763459, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '128', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249636, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCC(=O)Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4ccccc4[nH]3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL266325', 'parent_molecule_chembl_id': 'CHEMBL266325', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '124', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763460, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '124', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249637, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc4ccc(F)cc4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL7939', 'parent_molecule_chembl_id': 'CHEMBL7939', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '90', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763461, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '90', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249638, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)\\C=C\\c1ccc2OCOc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL596380', 'parent_molecule_chembl_id': 'CHEMBL596380', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '104', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763462, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '104', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249639, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1ccc(NC(=O)c2ccccc2NCc3ccncc3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL101683', 'parent_molecule_chembl_id': 'CHEMBL101683', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '110', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763463, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '110', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249640, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1N=C(N)c2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c4ncnc1c24', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL331237', 'parent_molecule_chembl_id': 'CHEMBL331237', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '131', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763464, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '131', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249641, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL35820', 'parent_molecule_chembl_id': 'CHEMBL35820', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '36', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763465, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249642, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc2[nH]c(cc2c1)C(=O)c3cc4cc(O)ccc4[nH]3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL377193', 'parent_molecule_chembl_id': 'CHEMBL377193', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '27', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763466, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '27', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249643, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(O)c(Br)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL473773', 'parent_molecule_chembl_id': 'CHEMBL473773', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763467, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249644, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(N3CCN(CC3)C(=O)Nc4ccc(Oc5ccccc5)cc4)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL102346', 'parent_molecule_chembl_id': 'CHEMBL102346', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '110', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763468, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '110', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249645, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)C(=C1Nc2ccccc2)c3cn(CCCn4ccnc4)c5ccccc35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL366266', 'parent_molecule_chembl_id': 'CHEMBL366266', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '111', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763469, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '111', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249646, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'c1ccc(nc1)c2n[nH]cc2c3ccnc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261454', 'parent_molecule_chembl_id': 'CHEMBL261454', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '64', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763470, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '64', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249647, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1289494', 'parent_molecule_chembl_id': 'CHEMBL1289494', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '-2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763471, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '-2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249648, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccccc2N1C3CCN(Cc4ccc(cc4)c5nc6cc7[nH]cnc7cc6nc5c8ccccc8)CC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL258844', 'parent_molecule_chembl_id': 'CHEMBL258844', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '117', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763472, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '117', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249649, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1C=C(Oc2c1ccc3ccccc23)N4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL104468', 'parent_molecule_chembl_id': 'CHEMBL104468', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '116', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763473, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '116', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249650, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261849', 'parent_molecule_chembl_id': 'CHEMBL261849', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '113', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763474, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '113', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249651, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL596674', 'parent_molecule_chembl_id': 'CHEMBL596674', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763475, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249652, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL120077', 'parent_molecule_chembl_id': 'CHEMBL120077', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '12', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763476, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249653, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\\C=C(/C)\\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\\C=C\\C=C\\C=C(/C)\\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL413', 'parent_molecule_chembl_id': 'CHEMBL413', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '119', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763477, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '119', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249654, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cccc(n1)c2[nH]c(nc2c3ccc4OCOc4c3)C(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL226838', 'parent_molecule_chembl_id': 'CHEMBL226838', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '108', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763478, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '108', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249655, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1ccc2NC(=O)\\C(=C\\c3cc4CCCCc4[nH]3)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218925', 'parent_molecule_chembl_id': 'CHEMBL2218925', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763479, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249656, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCCCN1c2ccccc2Oc3ccc(Cl)cc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1398474', 'parent_molecule_chembl_id': 'CHEMBL1398474', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '140', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763480, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '140', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249657, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(=O)c1ccc(cc1O)N2CCOCC2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1317546', 'parent_molecule_chembl_id': 'CHEMBL1317546', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '110', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763481, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '110', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249658, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cn1c2ccccc2c3c4C(=O)NCc4c5c6ccccc6n(CCC#N)c5c13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL302449', 'parent_molecule_chembl_id': 'CHEMBL302449', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '85', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763482, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '85', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249659, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccc(cc2/C/1=C\\c3ccc[nH]3)c4cccnc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218929', 'parent_molecule_chembl_id': 'CHEMBL2218929', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '59', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763483, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '59', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249660, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccccc4C)cc3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218930', 'parent_molecule_chembl_id': 'CHEMBL2218930', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763484, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249661, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'c1ccc2c(c[nH]c2c1)c3ccncc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL380071', 'parent_molecule_chembl_id': 'CHEMBL380071', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '110', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763485, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '110', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249662, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(C=C(C#N)C#N)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL77456', 'parent_molecule_chembl_id': 'CHEMBL77456', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '106', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763486, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '106', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249663, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(C)c(\\C=C\\2/C(=O)Nc3ccccc23)[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL276711', 'parent_molecule_chembl_id': 'CHEMBL276711', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763487, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249664, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1c2ccccc2c3nc4nnnn4nc13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL599894', 'parent_molecule_chembl_id': 'CHEMBL599894', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '110', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763488, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '110', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249665, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cccc(c1)c2nc(N3CCOCC3)c4oc5ncccc5c4n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL573339', 'parent_molecule_chembl_id': 'CHEMBL573339', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763489, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249666, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc2c(c1)c(cn2CCCN(C)C)C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261491', 'parent_molecule_chembl_id': 'CHEMBL261491', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '113', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763490, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '113', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249667, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1ncnc2c1c(cn2C3CCCC3)c4ccc(Oc5ccccc5)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL47940', 'parent_molecule_chembl_id': 'CHEMBL47940', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '80', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763491, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '80', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249668, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ccc3ncsc3c2/C/1=C/c4c[nH]cn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL235641', 'parent_molecule_chembl_id': 'CHEMBL235641', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763492, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249669, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H]1CN(CCCN1S(=O)(=O)c2cccc3cncc(C)c23)C(=O)CN', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218931', 'parent_molecule_chembl_id': 'CHEMBL2218931', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '106', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763493, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '106', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249670, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(\\C=C(/C#N)\\C(=O)NCc2ccccc2)cc1O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL56543', 'parent_molecule_chembl_id': 'CHEMBL56543', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '105', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763494, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '105', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249671, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2cnc3c(cnn3c2)c4ccsc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL92461', 'parent_molecule_chembl_id': 'CHEMBL92461', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763495, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249672, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(NC(=O)c4ccccc4)cc3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL382590', 'parent_molecule_chembl_id': 'CHEMBL382590', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '124', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763496, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '124', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249673, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)C(=C2CCN(CCN3C(=S)Nc4ccccc4C3=O)CC2)c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261131', 'parent_molecule_chembl_id': 'CHEMBL261131', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763497, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249674, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'o1c2ccccc2c3[nH]nc(c4ccccc4)c13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL406375', 'parent_molecule_chembl_id': 'CHEMBL406375', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '115', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763498, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '115', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249675, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1C=C(Oc2c1cccc2c3ccccc3)N4CCOCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL98350', 'parent_molecule_chembl_id': 'CHEMBL98350', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '108', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763499, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '108', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249676, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(Cl)cc(\\C=C\\2/C(=O)Nc3ccc(Cl)cc23)cc1Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218932', 'parent_molecule_chembl_id': 'CHEMBL2218932', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '80', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763500, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '80', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249677, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35)N(C)C(=O)c9ccccc9', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL608533', 'parent_molecule_chembl_id': 'CHEMBL608533', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '77', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763501, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '77', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249678, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=C(C#N)C#N)\\C(=C\\c1ccc(O)cc1)\\C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL76589', 'parent_molecule_chembl_id': 'CHEMBL76589', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763502, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249679, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1cc(ccc1C(=O)c2ccccc2)N3CCOCC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL478980', 'parent_molecule_chembl_id': 'CHEMBL478980', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763503, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249680, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1cccc(c1)c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL483847', 'parent_molecule_chembl_id': 'CHEMBL483847', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '88', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763504, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '88', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249681, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)c1ccc(\\C=C\\2/C(=O)Nc3ccccc23)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL328710', 'parent_molecule_chembl_id': 'CHEMBL328710', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '103', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763505, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '103', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249682, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CO[C@H]1C[C@H](C)[C@@H](OC)C2=CC(=O)C=C(NC(=O)\\C(=C\\C=C\\[C@H](OC)[C@@H](OC(=O)N)\\C(=C\\[C@H](C)[C@H]1OC)\\C)\\C)C2=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL479533', 'parent_molecule_chembl_id': 'CHEMBL479533', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '111', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763506, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '111', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249683, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1C=C(Oc2c1cccc2c3ccccc3)N4CCNCC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1363184', 'parent_molecule_chembl_id': 'CHEMBL1363184', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763507, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249684, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)\\C(=C/c2ccc3nccnc3c2)\\S1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218934', 'parent_molecule_chembl_id': 'CHEMBL2218934', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763508, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249685, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL97771', 'parent_molecule_chembl_id': 'CHEMBL97771', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763509, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249686, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc2ncc(nc2cc1C)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL7724', 'parent_molecule_chembl_id': 'CHEMBL7724', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763510, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249687, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL383899', 'parent_molecule_chembl_id': 'CHEMBL383899', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763511, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249688, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL7463', 'parent_molecule_chembl_id': 'CHEMBL7463', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '90', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763512, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '90', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249689, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2cc1OC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL563845', 'parent_molecule_chembl_id': 'CHEMBL563845', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '103', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763513, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '103', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249690, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(CN1CCCC1)Oc2ccc(Nc3ncc(s3)c4ccccc4)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218935', 'parent_molecule_chembl_id': 'CHEMBL2218935', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '46', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763514, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '46', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249691, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(c1cccc(Cl)c1)S(=O)(=O)c2ccc3NC(=O)\\C(=C/C4=C(C)C(=C(C)C4)C(=O)N5CCN(C)CC5)\\c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218936', 'parent_molecule_chembl_id': 'CHEMBL2218936', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763515, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249692, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'FC1(F)Oc2ccc(\\C=C\\3/SC(=O)NC3=O)cc2O1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1231533', 'parent_molecule_chembl_id': 'CHEMBL1231533', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763516, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249693, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCNC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccc(Cl)cc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL13485', 'parent_molecule_chembl_id': 'CHEMBL13485', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '47', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763517, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '47', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249694, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc2ncc(nc2cc1OC)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL71191', 'parent_molecule_chembl_id': 'CHEMBL71191', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763518, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249695, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL388978', 'parent_molecule_chembl_id': 'CHEMBL388978', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '1', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763519, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249696, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN([C@@H](Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)C(=O)N4CCN(CC4)c5ccccc5)S(=O)(=O)c6cccc7cnccc67', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL28324', 'parent_molecule_chembl_id': 'CHEMBL28324', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '101', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763520, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '101', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249697, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nc(Nc2ccc(cc2)S(=O)(=O)N)nn1C(=O)c3c(F)cccc3F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL191003', 'parent_molecule_chembl_id': 'CHEMBL191003', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '34', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763521, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '34', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249698, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1ccc2c(c1)[nH]c3c4[nH]c5ccccc5c4c6C(=O)NC(=O)c6c23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL64758', 'parent_molecule_chembl_id': 'CHEMBL64758', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '109', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763522, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '109', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249699, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](N)[C@@H]1CC[C@H](CC1)C(=O)Nc2ccncc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL559147', 'parent_molecule_chembl_id': 'CHEMBL559147', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '107', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763523, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '107', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249700, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)S(=O)(=O)c1ccc2NC(=O)\\C(=C/c3cc4CCCCc4[nH]3)\\c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL605003', 'parent_molecule_chembl_id': 'CHEMBL605003', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '114', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763524, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '114', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249701, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1ccc(NC(=O)CCCc2ccc(cc2)c3ccccc3F)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL235658', 'parent_molecule_chembl_id': 'CHEMBL235658', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '105', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763525, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '105', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249702, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CSc1nc(c2ccc(F)cc2)c([nH]1)c3ccnc(NC(C)c4ccccc4)c3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL111364', 'parent_molecule_chembl_id': 'CHEMBL111364', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '113', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763526, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '113', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249703, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[S+]([O-])c1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL10', 'parent_molecule_chembl_id': 'CHEMBL10', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '86', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763527, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '86', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249704, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1C=C(OC(=C1)c2cccc3Sc4ccccc4Sc23)N5CCOCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL222102', 'parent_molecule_chembl_id': 'CHEMBL222102', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '97', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763528, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '97', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249705, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1[nH]c2ccccc2c1c3[nH]c4ccccc4c3N=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL126077', 'parent_molecule_chembl_id': 'CHEMBL126077', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '30', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763529, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '30', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249706, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(OC)c2C(=S)c3ccccc3Nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1331734', 'parent_molecule_chembl_id': 'CHEMBL1331734', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '116', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763530, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '116', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249707, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1n[nH]c2nnc(cc12)c3c(nn4ccccc34)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL259551', 'parent_molecule_chembl_id': 'CHEMBL259551', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '66', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763531, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '66', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249708, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1cc(Nc2nc(nc3ccccc23)c4ccccc4)n[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL359482', 'parent_molecule_chembl_id': 'CHEMBL359482', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763532, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249709, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCOc1nc(NC(=O)Cc2cc(OC)ccc2OC)cc(N)c1C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL210618', 'parent_molecule_chembl_id': 'CHEMBL210618', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '106', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763533, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '106', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249710, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1c(c2ccc(F)cc2)c(nn1c3ccc(Cl)cc3)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL91730', 'parent_molecule_chembl_id': 'CHEMBL91730', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '105', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763534, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '105', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249711, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=S(=O)(N1CCCNCC1)c2cccc3cnccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL38380', 'parent_molecule_chembl_id': 'CHEMBL38380', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '94', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763535, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '94', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249712, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1cc(NC(=S)NC(NC(=O)C(c2ccccc2)c3ccccc3)C(Cl)(Cl)Cl)ccc1F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1221601', 'parent_molecule_chembl_id': 'CHEMBL1221601', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '115', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763536, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '115', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249713, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(cc1)S(=O)(=O)\\C=C\\C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL403183', 'parent_molecule_chembl_id': 'CHEMBL403183', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763537, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249714, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC2=CC(=O)c3sc(C)nc3C2=O)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL290904', 'parent_molecule_chembl_id': 'CHEMBL290904', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '122', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763538, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '122', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249715, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Oc1n[nH]c2nnc(cc12)c3c(nn4ccccc34)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2218938', 'parent_molecule_chembl_id': 'CHEMBL2218938', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '95', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763539, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '95', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249716, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)c2c1c3c4ccccc4[nH]c3n5cncc25', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL413188', 'parent_molecule_chembl_id': 'CHEMBL413188', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '91', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763540, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '91', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249717, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COC(=O)[C@@]1(O)C[C@H]2O[C@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL281948', 'parent_molecule_chembl_id': 'CHEMBL281948', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '79', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763541, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '79', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249718, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cccc(C2=CC(=O)c3ccccc3O2)c1N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL35482', 'parent_molecule_chembl_id': 'CHEMBL35482', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '115', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763542, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '115', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249719, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1NC(=O)c2c1c3c4ccccc4n5C6CCC(O6)n7c8ccccc8c2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL304428', 'parent_molecule_chembl_id': 'CHEMBL304428', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '103', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763543, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '103', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249720, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1ccc2[nH]c3c(CC(=O)Nc4ccccc34)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL50894', 'parent_molecule_chembl_id': 'CHEMBL50894', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '81', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763544, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '81', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249721, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1cnc2c(NCc3ccccc3)nc(NCCCO)nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL83980', 'parent_molecule_chembl_id': 'CHEMBL83980', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '93', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763545, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '93', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249722, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN1\\C(=C\\C(=O)C)\\Sc2ccc(OC)cc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL408982', 'parent_molecule_chembl_id': 'CHEMBL408982', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763546, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249723, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1c2ccccc2[n+]3ccc4c5ccccc5[nH]c4c13', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL602937', 'parent_molecule_chembl_id': 'CHEMBL602937', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '111', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763547, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '111', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249724, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(OC)c(\\C=C\\2/C(=O)Nc3ccccc23)c(OC)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL404941', 'parent_molecule_chembl_id': 'CHEMBL404941', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '123', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763548, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '123', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249725, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Brc1ccc2[nH]c3c(CC(=O)Nc4ccccc34)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL296586', 'parent_molecule_chembl_id': 'CHEMBL296586', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763549, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249726, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1ccc(cc1)c2nc(c3ccc(F)cc3)c([nH]2)c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL17331', 'parent_molecule_chembl_id': 'CHEMBL17331', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '82', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763550, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '82', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249727, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1oc(c2ccncc2)c(n1)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL36450', 'parent_molecule_chembl_id': 'CHEMBL36450', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763551, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249728, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': '[O-][N+](=O)c1ccc2[nH]c3c(CC(=O)Nc4ccc(CCC#N)cc34)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL260138', 'parent_molecule_chembl_id': 'CHEMBL260138', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '48', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763552, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '48', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249729, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Clc1[nH]c2ccccc2c1\\C=C/3\\C(=O)Nc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261425', 'parent_molecule_chembl_id': 'CHEMBL261425', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '116', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763553, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '116', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249730, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1ccc2[nH]c(nc2c1)c3ccc(Oc4ccc(Cl)cc4)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL179583', 'parent_molecule_chembl_id': 'CHEMBL179583', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '128', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763554, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '128', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249731, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1SC(=O)N(Cc2ccccc2)C1=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL284861', 'parent_molecule_chembl_id': 'CHEMBL284861', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '118', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763555, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '118', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249732, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL257167', 'parent_molecule_chembl_id': 'CHEMBL257167', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '71', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763556, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '71', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249733, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)S(=O)(=O)N(CCO)c2ccccc2CN(C)C\\C=C\\c3ccc(Cl)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL155333', 'parent_molecule_chembl_id': 'CHEMBL155333', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '116', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763557, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '116', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249734, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Nc1nccc(n1)c2c(ncn2C3CCNCC3)c4ccc(F)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL274064', 'parent_molecule_chembl_id': 'CHEMBL274064', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '108', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763558, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '108', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249735, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(cc1)c2nc3SCCn3c2c4ccncc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL313417', 'parent_molecule_chembl_id': 'CHEMBL313417', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '96', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763559, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '96', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249736, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCCc1c([nH]c2nccnc12)c3ccc(O)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL75680', 'parent_molecule_chembl_id': 'CHEMBL75680', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763560, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249737, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@@H]4CCCC[C@@H]4N)nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL367625', 'parent_molecule_chembl_id': 'CHEMBL367625', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '62', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763561, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '62', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249738, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)n1cnc2\\C(=N\\c3cccc(Cl)c3)\\N=C(NCCO)Nc12', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL311228', 'parent_molecule_chembl_id': 'CHEMBL311228', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '52', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763562, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '52', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12249739, 'assay_chembl_id': 'CHEMBL2218946', 'assay_description': 'Millipore: Percentage of residual kinase activity of ABL2 at 1uM relative to control. Control inhibitor: Staurosporine at 10.0uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Ic1cccc(CSc2oc(nn2)c3ccncc3)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2218924', 'document_journal': 'Biochem. J.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL288064', 'parent_molecule_chembl_id': 'CHEMBL288064', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Residual Activity', 'published_units': '%', 'published_value': '112', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1763563, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Residual Activity', 'standard_units': '%', 'standard_value': '112', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12626717, 'assay_chembl_id': 'CHEMBL2316989', 'assay_description': 'Inhibition of ABL2 (unknown origin) at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1cc(Nc2ncc(Cl)c(n2)c3cccc(CC#N)c3)ccc1N4CCN(C)CC4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2311352', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2312140', 'parent_molecule_chembl_id': 'CHEMBL2312140', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>=', 'published_type': 'INH', 'published_units': '%', 'published_value': '80', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1841678, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '80', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12657837, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccc(Cn3ccnc3)c(c2)C(F)(F)F)cc1C#Cc4cncnc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '16.03', 'le': '0.3', 'lle': '3.35', 'sei': '10.18'}, 'molecule_chembl_id': 'CHEMBL2324932', 'parent_molecule_chembl_id': 'CHEMBL2324932', 'pchembl_value': '7.4', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '40', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851152, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '40', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657839, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccc(Cn3ccnc3)c(c2)C(F)(F)F)cc1C#Cc4cncnc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '14.71', 'le': '0.27', 'lle': '2.74', 'sei': '9.34'}, 'molecule_chembl_id': 'CHEMBL2324932', 'parent_molecule_chembl_id': 'CHEMBL2324932', 'pchembl_value': '6.79', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '163', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851152, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '163', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657841, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccc(CN3CCN(CCO)CC3)c(c2)C(F)(F)F)cc1C#Cc4cnc5ccccn45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '13.79', 'le': '0.26', 'lle': '2.93', 'sei': '10.59'}, 'molecule_chembl_id': 'CHEMBL2324931', 'parent_molecule_chembl_id': 'CHEMBL2324931', 'pchembl_value': '7.75', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '18', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851151, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657843, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccc(CN3CCN(CCO)CC3)c(c2)C(F)(F)F)cc1C#Cc4cnc5ccccn45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '13.15', 'le': '0.25', 'lle': '2.58', 'sei': '10.1'}, 'molecule_chembl_id': 'CHEMBL2324931', 'parent_molecule_chembl_id': 'CHEMBL2324931', 'pchembl_value': '7.39', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '41', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851151, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '41', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657845, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc3ccc(C)c(c3)C#Cc4cnc5cccnn45)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '15.2', 'le': '0.28', 'lle': '3.22', 'sei': '12.31'}, 'molecule_chembl_id': 'CHEMBL2324930', 'parent_molecule_chembl_id': 'CHEMBL2324930', 'pchembl_value': '8.1', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '8', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851150, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '8', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657847, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc3ccc(C)c(c3)C#Cc4cnc5cccnn45)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '13.91', 'le': '0.26', 'lle': '2.53', 'sei': '11.26'}, 'molecule_chembl_id': 'CHEMBL2324930', 'parent_molecule_chembl_id': 'CHEMBL2324930', 'pchembl_value': '7.41', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '39', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851150, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '39', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657849, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4ccc(N)nc4)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '14.52', 'le': '0.27', 'lle': '3.71', 'sei': '7.13'}, 'molecule_chembl_id': 'CHEMBL2324929', 'parent_molecule_chembl_id': 'CHEMBL2324929', 'pchembl_value': '7.44', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '36', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851149, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '36', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657851, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4ccc(N)nc4)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '14', 'le': '0.26', 'lle': '3.44', 'sei': '6.88'}, 'molecule_chembl_id': 'CHEMBL2324929', 'parent_molecule_chembl_id': 'CHEMBL2324929', 'pchembl_value': '7.17', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '67', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851149, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '67', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657853, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cccnc4)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '15.79', 'le': '0.3', 'lle': '3.92', 'sei': '10.03'}, 'molecule_chembl_id': 'CHEMBL2324928', 'parent_molecule_chembl_id': 'CHEMBL2324928', 'pchembl_value': '7.85', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '14', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851148, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657855, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cccnc4)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '14.43', 'le': '0.27', 'lle': '3.25', 'sei': '9.17'}, 'molecule_chembl_id': 'CHEMBL2324928', 'parent_molecule_chembl_id': 'CHEMBL2324928', 'pchembl_value': '7.18', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '66', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851148, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '66', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657857, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5ccccn45)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '14.76', 'le': '0.28', 'lle': '3.67', 'sei': '9.57'}, 'molecule_chembl_id': 'CHEMBL2324927', 'parent_molecule_chembl_id': 'CHEMBL2324927', 'pchembl_value': '7.92', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '12', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851147, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '12', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657859, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5ccccn45)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2324927', 'parent_molecule_chembl_id': 'CHEMBL2324927', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851147, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657861, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccc(Cn3ccnc3)c(c2)C(F)(F)F)cc1C#Cc4ncc(Nc5ccccc5)cn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '11.81', 'le': '0.22', 'lle': '0.83', 'sei': '7.7'}, 'molecule_chembl_id': 'CHEMBL2321908', 'parent_molecule_chembl_id': 'CHEMBL2321908', 'pchembl_value': '6.53', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '298', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851146, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '298', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657863, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(NC(=O)c2ccc(Cn3ccnc3)c(c2)C(F)(F)F)cc1C#Cc4ncc(Nc5ccccc5)cn4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2321908', 'parent_molecule_chembl_id': 'CHEMBL2321908', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851146, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657874, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5cccnn45)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '15.3', 'le': '0.29', 'lle': '4.43', 'sei': '8.6'}, 'molecule_chembl_id': 'CHEMBL2324926', 'parent_molecule_chembl_id': 'CHEMBL2324926', 'pchembl_value': '8.22', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '6', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851145, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '6', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657876, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5cccnn45)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '13.63', 'le': '0.26', 'lle': '3.54', 'sei': '7.66'}, 'molecule_chembl_id': 'CHEMBL2324926', 'parent_molecule_chembl_id': 'CHEMBL2324926', 'pchembl_value': '7.33', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '47', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851145, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '47', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657887, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5cnccn45)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '14.88', 'le': '0.28', 'lle': '4.9', 'sei': '8.37'}, 'molecule_chembl_id': 'CHEMBL2324925', 'parent_molecule_chembl_id': 'CHEMBL2324925', 'pchembl_value': '8', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851144, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '10', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657889, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5cnccn45)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '15.86', 'le': '0.3', 'lle': '5.42', 'sei': '8.91'}, 'molecule_chembl_id': 'CHEMBL2324925', 'parent_molecule_chembl_id': 'CHEMBL2324925', 'pchembl_value': '8.52', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '3', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851144, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657900, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc4cncc5nccn45)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '16.9', 'le': '0.32', 'lle': '4.8', 'sei': '13.68'}, 'molecule_chembl_id': 'CHEMBL2324924', 'parent_molecule_chembl_id': 'CHEMBL2324924', 'pchembl_value': '9', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '1', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851143, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '1', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657902, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc4cncc5nccn45)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '16.33', 'le': '0.3', 'lle': '4.5', 'sei': '13.23'}, 'molecule_chembl_id': 'CHEMBL2324924', 'parent_molecule_chembl_id': 'CHEMBL2324924', 'pchembl_value': '8.7', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '2', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851143, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657913, 'assay_chembl_id': 'CHEMBL2330092', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cncc5nccn45)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '14.56', 'le': '0.27', 'lle': '4.72', 'sei': '8.18'}, 'molecule_chembl_id': 'CHEMBL2324923', 'parent_molecule_chembl_id': 'CHEMBL2324923', 'pchembl_value': '7.82', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '15', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851142, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12657915, 'assay_chembl_id': 'CHEMBL2330094', 'assay_description': 'Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 mins by platform assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cncc5nccn45)n(C)n3)cc2C(F)(F)F)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2321864', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': {'bei': '14.81', 'le': '0.28', 'lle': '4.86', 'sei': '8.32'}, 'molecule_chembl_id': 'CHEMBL2324923', 'parent_molecule_chembl_id': 'CHEMBL2324923', 'pchembl_value': '7.96', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '11', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1851142, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '11', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12693260, 'assay_chembl_id': 'CHEMBL2343945', 'assay_description': 'Inhibition of ARG (unknown origin)', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1c(F)c(ccc1C(=O)N2CCOc3ccc(cc3C2)c4ccc(N)nc4)S(=O)(=O)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2331117', 'document_journal': 'J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2333365', 'parent_molecule_chembl_id': 'CHEMBL2333365', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '10000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1867358, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 12728897, 'assay_chembl_id': 'CHEMBL2350229', 'assay_description': 'Inhibition of ARG (unknown origin) assessed as remaining activity at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ncc(nc2N1CCC3CCOCC3)c4ccc(cc4)c5nc[nH]n5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2346597', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2348865', 'parent_molecule_chembl_id': 'CHEMBL2348865', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '87', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1876973, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '87', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12730039, 'assay_chembl_id': 'CHEMBL2353914', 'assay_description': 'Inhibition of ARG (unknown origin) assessed as remaining activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(O)c1ccc(cn1)c2cnc3NC(=O)CN(CC4CCOCC4)c3n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2346597', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2348862', 'parent_molecule_chembl_id': 'CHEMBL2348862', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '99', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1876970, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '99', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12730942, 'assay_chembl_id': 'CHEMBL2350114', 'assay_description': 'Inhibition of ABL2 (unknown origin) using [gamma-33P]ATP assessed as residual activity at 3 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCc1ccc(cc1)c2ccc3N(C)S(=O)(=O)c4cn[nH]c4c3c2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2346629', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2333445', 'parent_molecule_chembl_id': 'CHEMBL2333445', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '90', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1877341, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '90', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 12731176, 'assay_chembl_id': 'CHEMBL2350229', 'assay_description': 'Inhibition of ARG (unknown origin) assessed as remaining activity at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(O)c1ccc(cn1)c2cnc3NC(=O)CN(CC4CCOCC4)c3n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2346597', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2348862', 'parent_molecule_chembl_id': 'CHEMBL2348862', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '92', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1876970, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '92', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13301268, 'assay_chembl_id': 'CHEMBL2384609', 'assay_description': 'Inhibition of Arg (unknown origin)', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Fc1ccc(C(=O)Nc2ccc(Nc3ccnc4NC(=O)c5ccccc5c34)cc2)c(c1)C(F)(F)F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2380198', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': {'bei': '12.31', 'le': '0.23', 'lle': '0.89', 'sei': '7.3'}, 'molecule_chembl_id': 'CHEMBL2380834', 'parent_molecule_chembl_id': 'CHEMBL2380834', 'pchembl_value': '6.06', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '863', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 1893341, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '863', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': 'Not Active', 'activity_id': 13335959, 'assay_chembl_id': 'CHEMBL2393924', 'assay_description': 'Inhibition of ABL2 (unknown origin) transfected in mouse Ba/F3 cells up to 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000219', 'bao_label': 'cell-based format', 'canonical_smiles': 'Fc1ccc(cc1Cl)c2n[nH]cc2c3ccncc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2390926', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2390985', 'parent_molecule_chembl_id': 'CHEMBL2390985', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1898575, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 13336006, 'assay_chembl_id': 'CHEMBL2394053', 'assay_description': 'Inhibition of ABL2 (unknown origin) transfected in mouse Ba/F3 cells at 5 uM after 24 hrs', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000219', 'bao_label': 'cell-based format', 'canonical_smiles': 'Cc1ccc(cc1)n2cnc3cc(Nc4nnc(C)c5ccccc45)ccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2390926', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2390986', 'parent_molecule_chembl_id': 'CHEMBL2390986', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1898576, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Active', 'activity_id': 13336007, 'assay_chembl_id': 'CHEMBL2394053', 'assay_description': 'Inhibition of ABL2 (unknown origin) transfected in mouse Ba/F3 cells at 5 uM after 24 hrs', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000219', 'bao_label': 'cell-based format', 'canonical_smiles': 'Fc1ccc(cc1Cl)c2n[nH]cc2c3ccncc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2390926', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2390985', 'parent_molecule_chembl_id': 'CHEMBL2390985', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1898575, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 13336077, 'assay_chembl_id': 'CHEMBL2394077', 'assay_description': 'Inhibition of ABL2 (unknown origin) transfected in mouse Ba/F3 cells at 1 uM after 24 hrs', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000219', 'bao_label': 'cell-based format', 'canonical_smiles': 'Cc1cccc(c1)C(=O)Nc2cc(n[nH]2)c3ccc(F)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2390926', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2390984', 'parent_molecule_chembl_id': 'CHEMBL2390984', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1898574, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 13336078, 'assay_chembl_id': 'CHEMBL2394077', 'assay_description': 'Inhibition of ABL2 (unknown origin) transfected in mouse Ba/F3 cells at 1 uM after 24 hrs', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000219', 'bao_label': 'cell-based format', 'canonical_smiles': 'Cc1ccc(cc1)c2cc(NC(=O)c3ccc(F)cc3)[nH]n2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2390926', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2390983', 'parent_molecule_chembl_id': 'CHEMBL2390983', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1898573, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 13336079, 'assay_chembl_id': 'CHEMBL2394077', 'assay_description': 'Inhibition of ABL2 (unknown origin) transfected in mouse Ba/F3 cells at 1 uM after 24 hrs', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000219', 'bao_label': 'cell-based format', 'canonical_smiles': 'COc1ccc(cc1)C(=O)Nc2cc([nH]n2)c3ccccc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2390926', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL167454', 'parent_molecule_chembl_id': 'CHEMBL167454', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1901750, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 13349238, 'assay_chembl_id': 'CHEMBL2399730', 'assay_description': 'Inhibition of recombinant ABL-2 (unknown origin) at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1ccc(O[C@@H]2CC[C@H](CC2)NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2396585', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2397148', 'parent_molecule_chembl_id': 'CHEMBL2397148', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1902506, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Not Active', 'activity_id': 13349239, 'assay_chembl_id': 'CHEMBL2399730', 'assay_description': 'Inhibition of recombinant ABL-2 (unknown origin) at 10 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000376', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC(=O)c1ccc(O[C@@H]2CC[C@H](CC2)NC(=O)NC34CC5CC(CC(C5)C3)C4)cc1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2396585', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL242459', 'parent_molecule_chembl_id': 'CHEMBL242459', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'INH', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 1902505, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Inhibition', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 13372443, 'assay_chembl_id': 'CHEMBL2406464', 'assay_description': 'Inhibition of ARG (unknown origin) autophosphorylation at 1 uM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C[C@@H](Oc1c(N)ncc2c(coc12)C3=CCN(CC3)C(=O)N)c4c(Cl)ccc(F)c4Cl', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2401646', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2401832', 'parent_molecule_chembl_id': 'CHEMBL2401832', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1904653, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13375955, 'assay_chembl_id': 'CHEMBL2406115', 'assay_description': 'Inhibition of ABL2 (unknown origin) at 10 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC[C@H]1N(c2ccn(C)n2)c3nc(ncc3N(C)C1=O)n4ccnc4c5ccc(F)cc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2401733', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2402081', 'parent_molecule_chembl_id': 'CHEMBL2402081', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1904979, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13419637, 'assay_chembl_id': 'CHEMBL2422085', 'assay_description': 'Inhibition of ARG (unknown origin) at 30 uM by microfluidic mobility shift assay relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(C1CCC2(CCN(CC2)c3ncnc4[nH]cnc34)NC1)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2417369', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2420901', 'parent_molecule_chembl_id': 'CHEMBL2420901', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '18', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1917184, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '18', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13419638, 'assay_chembl_id': 'CHEMBL2422085', 'assay_description': 'Inhibition of ARG (unknown origin) at 30 uM by microfluidic mobility shift assay relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C(C1CCNC2(CCN(CC2)c3ncnc4[nH]cnc34)C1)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2417369', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2420900', 'parent_molecule_chembl_id': 'CHEMBL2420900', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '13', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1917183, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '13', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13419639, 'assay_chembl_id': 'CHEMBL2422085', 'assay_description': 'Inhibition of ARG (unknown origin) at 30 uM by microfluidic mobility shift assay relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'C1CC(CC2(CCN(CC2)c3ncnc4[nH]cnc34)N1)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2417369', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2420899', 'parent_molecule_chembl_id': 'CHEMBL2420899', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '23', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1917182, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '23', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13442407, 'assay_chembl_id': 'CHEMBL2428030', 'assay_description': 'Competitive binding affinity to ABL2 (unknown origin) at 10 uM in presence of ATP relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O[C@@H]1CC[C@H](CC1)Nc2nccc(n2)n3ccc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2424622', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2425646', 'parent_molecule_chembl_id': 'CHEMBL2425646', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1918688, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13445542, 'assay_chembl_id': 'CHEMBL2428030', 'assay_description': 'Competitive binding affinity to ABL2 (unknown origin) at 10 uM in presence of ATP relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O[C@@H]1CC[C@H](CC1)Nc2nccc(n2)c3n[nH]c4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2424622', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2425644', 'parent_molecule_chembl_id': 'CHEMBL2425644', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1918686, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13448597, 'assay_chembl_id': 'CHEMBL2428030', 'assay_description': 'Competitive binding affinity to ABL2 (unknown origin) at 10 uM in presence of ATP relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O[C@@H]1CC[C@H](CC1)Nc2nccc(n2)n3ncc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2424622', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2425645', 'parent_molecule_chembl_id': 'CHEMBL2425645', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1918687, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13448734, 'assay_chembl_id': 'CHEMBL2428030', 'assay_description': 'Competitive binding affinity to ABL2 (unknown origin) at 10 uM in presence of ATP relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C([C@@H]1CC[C@H](CC1)Nc2nccc(n2)n3nnc4ccccc34)N5CCOCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2424622', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2425649', 'parent_molecule_chembl_id': 'CHEMBL2425649', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1918691, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13451529, 'assay_chembl_id': 'CHEMBL2428030', 'assay_description': 'Competitive binding affinity to ABL2 (unknown origin) at 10 uM in presence of ATP relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'N[C@@H]1CC[C@H](CC1)Nc2nccc(n2)n3nnc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2424622', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2425652', 'parent_molecule_chembl_id': 'CHEMBL2425652', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '89', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1918694, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '89', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13454713, 'assay_chembl_id': 'CHEMBL2428030', 'assay_description': 'Competitive binding affinity to ABL2 (unknown origin) at 10 uM in presence of ATP relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O[C@@H]1CC[C@H](CC1)Nc2nccc(n2)n3nnc4ccccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL2424622', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2013, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL2425654', 'parent_molecule_chembl_id': 'CHEMBL2425654', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1918696, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13872208, 'assay_chembl_id': 'CHEMBL3102395', 'assay_description': 'Inhibition of human Arg assessed as residual activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'O=C1Nc2ncccc2/C/1=C\\3/Nc4ncccc4C3=O', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3098105', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3099673', 'parent_molecule_chembl_id': 'CHEMBL3099673', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '98', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1956912, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '98', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13906514, 'assay_chembl_id': 'CHEMBL3117706', 'assay_description': 'Inhibition of ARG (unknown origin) at 10 uM after 30 mins relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1OC)S(=O)(=O)Nc2cc(Sc3ncnc4nc[nH]c34)c(O)c5ccccc25', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3112530', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3113284', 'parent_molecule_chembl_id': 'CHEMBL3113284', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '8.2', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1963934, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '8.2', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13954567, 'assay_chembl_id': 'CHEMBL3132491', 'assay_description': 'Inhibition of human ARG assessed as residual activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nc3cc(cnc3[nH]2)c4csc(c4)C(=O)NCC(C)(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3124838', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3125726', 'parent_molecule_chembl_id': 'CHEMBL3125726', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '60', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1971373, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '60', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13954771, 'assay_chembl_id': 'CHEMBL3132491', 'assay_description': 'Inhibition of human ARG assessed as residual activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nc3cc(cnc3[nH]2)c4csc(c4)C(=O)NCCC(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3124838', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3125728', 'parent_molecule_chembl_id': 'CHEMBL3125728', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '52', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1971375, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '52', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13954782, 'assay_chembl_id': 'CHEMBL3132491', 'assay_description': 'Inhibition of human ARG assessed as residual activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COc1ccc(cc1)c2nc3cc(cnc3[nH]2)c4csc(c4)C(=O)NCC(C)C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3124838', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3125727', 'parent_molecule_chembl_id': 'CHEMBL3125727', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '38', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1971374, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '38', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13966007, 'assay_chembl_id': 'CHEMBL3135932', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 70 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'CNCc1ccc(cc1)c2ncnc3[nH]cnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL376388', 'parent_molecule_chembl_id': 'CHEMBL376388', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '33', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976699, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '33', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13966098, 'assay_chembl_id': 'CHEMBL3134668', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 1000 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'c1cnc2[nH]ccc2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL389685', 'parent_molecule_chembl_id': 'CHEMBL389685', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '40', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976698, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '40', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13974000, 'assay_chembl_id': 'CHEMBL3135900', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 0.1 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'C[C@H](CN(C)C)Oc1nc(Nc2cc3cccc(Cl)c3cn2)cnc1C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1928705', 'parent_molecule_chembl_id': 'CHEMBL1928705', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '1.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976697, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '1.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13974091, 'assay_chembl_id': 'CHEMBL3135602', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 0.35 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'COC(=O)c1cnc(Nc2cnc(cn2)C#N)cc1NCC3CCNCC3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1928692', 'parent_molecule_chembl_id': 'CHEMBL1928692', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '0', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976696, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13974182, 'assay_chembl_id': 'CHEMBL3137122', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 9 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'NCC1CN(CCO1)c2ncnc3[nH]c4cnccc4c23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL1928677', 'parent_molecule_chembl_id': 'CHEMBL1928677', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '6.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976695, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '6.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13974273, 'assay_chembl_id': 'CHEMBL3136251', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 90 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'NCC1CN(CCO1)c2ncnc3[nH]cnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL560373', 'parent_molecule_chembl_id': 'CHEMBL560373', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '23', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976694, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '23', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13975011, 'assay_chembl_id': 'CHEMBL3135307', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 420 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'C1CN(CCO1)c2ncnc3[nH]cnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL271138', 'parent_molecule_chembl_id': 'CHEMBL271138', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '54.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976693, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '54.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13975102, 'assay_chembl_id': 'CHEMBL3135556', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 0.02 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'NC1(CCN(CC1)c2ncnc3[nH]ccc23)C(=O)NCc4ccc(Cl)cc4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL598194', 'parent_molecule_chembl_id': 'CHEMBL598194', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '3', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976692, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13975193, 'assay_chembl_id': 'CHEMBL3135782', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 0.06 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'NC1(Cc2ccc(Cl)cc2)CCN(CC1)c3ncnc4[nH]ccc34', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL263664', 'parent_molecule_chembl_id': 'CHEMBL263664', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976691, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13975836, 'assay_chembl_id': 'CHEMBL3134759', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 2 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'NC1CCN(CC1)c2ncnc3[nH]ccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL259141', 'parent_molecule_chembl_id': 'CHEMBL259141', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '7.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976690, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '7.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13975927, 'assay_chembl_id': 'CHEMBL3136401', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 8 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'NCC1CCN(CC1)c2ncnc3[nH]ccc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL261249', 'parent_molecule_chembl_id': 'CHEMBL261249', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '3.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976689, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '3.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13976020, 'assay_chembl_id': 'CHEMBL3135220', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 0.2 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'Clc1ccc(cc1)C2(CCNCC2)c3ccc(cc3)c4ncnc5[nH]cnc45', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL228133', 'parent_molecule_chembl_id': 'CHEMBL228133', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '4.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1974515, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 13976111, 'assay_chembl_id': 'CHEMBL3136782', 'assay_description': 'Inhibition of human truncated Arg expressed in baculovirus assessed as substrate phosphorylation using fluorescence-labelled peptides as substrate at 95 uM after 90 mins by microfluidic peptide phosphorylation assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000019', 'bao_label': 'assay format', 'canonical_smiles': 'NCCc1ccc(cc1)c2ncnc3[nH]cnc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3132769', 'document_journal': 'MedChemComm', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL227727', 'parent_molecule_chembl_id': 'CHEMBL227727', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '50.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 1976700, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 14582439, 'assay_chembl_id': 'CHEMBL3240222', 'assay_description': 'Inhibition of human Abl2 assessed as enzyme activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCCS(=O)(=O)Nc1cccc(Nc2ccc3N=CN(C)C(=O)c3c2)c1C#N', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3232845', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3236464', 'parent_molecule_chembl_id': 'CHEMBL3236464', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '108', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2085596, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '108', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 14713702, 'assay_chembl_id': 'CHEMBL3296767', 'assay_description': 'Binding affinity to ARG (unknown origin)', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000192', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CCC(=O)Nc2c(C)[nH]c(\\C=C\\3/C(=O)Nc4ccc(F)cc34)c2C)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3286339', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2014, 'ligand_efficiency': {'bei': '15.85', 'le': '0.3', 'lle': '4.45', 'sei': '8.38'}, 'molecule_chembl_id': 'CHEMBL3288854', 'parent_molecule_chembl_id': 'CHEMBL3288854', 'pchembl_value': '6.75', 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'Ki', 'published_units': 'uM', 'published_value': '0.18', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 2116457, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Ki', 'standard_units': 'nM', 'standard_value': '180', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 14713738, 'assay_chembl_id': 'CHEMBL3296856', 'assay_description': 'Inhibition of ARG (unknown origin) at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN1CCN(CCC(=O)Nc2c(C)[nH]c(\\C=C\\3/C(=O)Nc4ccc(F)cc34)c2C)CC1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3286339', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3288854', 'parent_molecule_chembl_id': 'CHEMBL3288854', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '76', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2116457, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '76', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': 'Not Determined', 'activity_id': 14713760, 'assay_chembl_id': 'CHEMBL3296767', 'assay_description': 'Binding affinity to ARG (unknown origin)', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000192', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CCN(CC)CCNC(=O)c1c(C)[nH]c(\\C=C\\2/C(=O)Nc3ccc(F)cc23)c1C', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3286339', 'document_journal': 'Eur. J. Med. Chem.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL535', 'parent_molecule_chembl_id': 'CHEMBL535', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Ki', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 2116444, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Ki', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Active', 'activity_id': 15008678, 'assay_chembl_id': 'CHEMBL3364206', 'assay_description': 'Binding affinity to ABL2 (unknown origin)', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'Cc1ccc(O)cc1n2c(N)c(C(=O)N)c3nc4ccccc4nc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3351817', 'document_journal': 'J. Med. Chem.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3321809', 'parent_molecule_chembl_id': 'CHEMBL3321809', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 2253242, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Active', 'activity_id': 15008679, 'assay_chembl_id': 'CHEMBL3364206', 'assay_description': 'Binding affinity to ABL2 (unknown origin)', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1c(N)n(c2cccc(NC(=O)c3cccc(c3)C(F)(F)F)c2)c4nc5ccccc5nc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3351817', 'document_journal': 'J. Med. Chem.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3321811', 'parent_molecule_chembl_id': 'CHEMBL3321811', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 2253244, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': 'Active', 'activity_id': 15008680, 'assay_chembl_id': 'CHEMBL3364206', 'assay_description': 'Binding affinity to ABL2 (unknown origin)', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000375', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'NC(=O)c1c(N)n(c2cccc(c2)C(=O)Nc3cccc(c3)C(F)(F)F)c4nc5ccccc5nc14', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3351817', 'document_journal': 'J. Med. Chem.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3321816', 'parent_molecule_chembl_id': 'CHEMBL3321816', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': None, 'published_type': 'Activity', 'published_units': None, 'published_value': None, 'qudt_units': None, 'record_id': 2253249, 'src_id': 1, 'standard_flag': False, 'standard_relation': None, 'standard_type': 'Activity', 'standard_units': None, 'standard_value': None, 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': None}, {'activity_comment': None, 'activity_id': 15014102, 'assay_chembl_id': 'CHEMBL3361857', 'assay_description': 'Inhibition of ARG (unknown origin) at 100 nM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'OC[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c4ccc(Cl)c(F)c4', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3297705', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2014, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3298678', 'parent_molecule_chembl_id': 'CHEMBL3298678', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '0', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2261007, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '0', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 15736628, 'assay_chembl_id': 'CHEMBL3625823', 'assay_description': 'Inhibition of human recombinant Arg', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CN(C)CCCNC(=O)c1csc2nc(cn12)c3ccc(NC(=O)Nc4cc(on4)C(C)(C)C)cc3', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3621115', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2015, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3623375', 'parent_molecule_chembl_id': 'CHEMBL3623375', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 2505933, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 15756121, 'assay_chembl_id': 'CHEMBL3631607', 'assay_description': 'Inhibition of ABL2 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CS(=O)(=O)c1cccc(Nc2nccc(n2)c3sc(nc3c4cccc(NS(=O)(=O)c5c(F)cccc5F)c4)N6CCOCC6)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3627608', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2015, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3628627', 'parent_molecule_chembl_id': 'CHEMBL3628627', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '99.83', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2507619, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '99.83', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 15757716, 'assay_chembl_id': 'CHEMBL3631607', 'assay_description': 'Inhibition of ABL2 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'CC(C)(C)c1onc(NC(=O)Nc2ccc(Oc3ccncc3)cc2)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3627608', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2015, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL166031', 'parent_molecule_chembl_id': 'CHEMBL166031', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '90.14', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2507618, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '90.14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 15757978, 'assay_chembl_id': 'CHEMBL3631607', 'assay_description': 'Inhibition of ABL2 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': 'BAO_0000357', 'bao_label': 'single protein format', 'canonical_smiles': 'COCCNC(=O)c1ccc2c(c1)nc(c3cnc([nH]3)c4ccc(Cl)cc4)n2CCOC', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3627608', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2015, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3628628', 'parent_molecule_chembl_id': 'CHEMBL3628628', 'pchembl_value': None, 'potential_duplicate': False, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '59.29', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2507620, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '59.29', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16431721, 'assay_chembl_id': 'CHEMBL3749729', 'assay_description': 'Inhibition of human ABL2 using [EAIYAAPFAKKK] as substrate', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'CN1C(=O)C(=Cc2cnc(Nc3ccc4[nH]ccc4c3)nc12)S(=O)(=O)c5ccc(F)cc5F', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3745707', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3745885', 'parent_molecule_chembl_id': 'CHEMBL3745885', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'uM', 'published_value': '10', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 2741358, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '10000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 16450763, 'assay_chembl_id': 'CHEMBL3762149', 'assay_description': 'Inhibition of ARG (unknown origin) at 100 nM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'CC1(C)OCc2c(Nc3n[nH]c4ccccc34)nc(nc12)c5cn[nH]c5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3758169', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3758502', 'parent_molecule_chembl_id': 'CHEMBL3758502', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '69.5', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2747903, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '69.5', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16495333, 'assay_chembl_id': 'CHEMBL3776646', 'assay_description': 'Inhibition of N-terminal His6-tagged recombinant ARG (unknown origin) expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'Cn1cc(cn1)c2ccc(Cc3n[nH]c4ccc(cc34)C(=O)N5CCOCC5)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3774357', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3774885', 'parent_molecule_chembl_id': 'CHEMBL3774885', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '-15', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2763281, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '-15', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16508102, 'assay_chembl_id': 'CHEMBL3776646', 'assay_description': 'Inhibition of N-terminal His6-tagged recombinant ARG (unknown origin) expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'CNC(=O)c1ccc2[nH]nc(Cc3ccc4c(cnn4C)c3)c2c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3774357', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3775576', 'parent_molecule_chembl_id': 'CHEMBL3775576', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '20', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2763260, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '20', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16509079, 'assay_chembl_id': 'CHEMBL3776646', 'assay_description': 'Inhibition of N-terminal His6-tagged recombinant ARG (unknown origin) expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0001103', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'Cn1cc(cn1)c2ccc(Cc3n[nH]c4ccc(cc34)C(=O)N5CC[C@@H](O)C5)cc2', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3774357', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3775317', 'parent_molecule_chembl_id': 'CHEMBL3775317', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '=', 'published_type': 'Activity', 'published_units': '%', 'published_value': '14', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2763273, 'src_id': 1, 'standard_flag': False, 'standard_relation': '=', 'standard_type': 'Activity', 'standard_units': '%', 'standard_value': '14', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16593537, 'assay_chembl_id': 'CHEMBL3811540', 'assay_description': 'Inhibition of His-tagged full length human recombinant ARG expressed in baculovirus using Fluorescein-Poly GT as substrate at 100 nM', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'COC(=O)c1cc2cc(NCc3cc(NC(=O)c4cc(cc(c4)C(F)(F)F)n5cnc(C)c5)ccc3C)cnc2[nH]1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3808348', 'document_journal': 'J. Med. Chem.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3808884', 'parent_molecule_chembl_id': 'CHEMBL3808884', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '40', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2780310, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '40', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16613759, 'assay_chembl_id': 'CHEMBL3816552', 'assay_description': 'Inhibition of human ABL2 at 1 uM using [EAIYAAPFAKKK] as substrate', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3813650', 'document_journal': 'Bioorg. Med. Chem. Lett.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3815093', 'parent_molecule_chembl_id': 'CHEMBL3815093', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '=', 'published_type': 'INH', 'published_units': '%', 'published_value': '4', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2781972, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '4', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16618280, 'assay_chembl_id': 'CHEMBL3817005', 'assay_description': 'Inhibition of full length recombinant human C-terminal His-tagged cytoplasmic ARG expressed in baculovirus expression system at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'CC1(C)OCCn2c1nc3c(nc(nc23)c4cnc(N)nc4)N5CCOCC5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3813614', 'document_journal': 'ACS Med. Chem. Lett.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3813842', 'parent_molecule_chembl_id': 'CHEMBL3813842', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '<', 'published_type': 'INH', 'published_units': '%', 'published_value': '50', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2781546, 'src_id': 1, 'standard_flag': True, 'standard_relation': '<', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '50', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16619677, 'assay_chembl_id': 'CHEMBL3820245', 'assay_description': 'Inhibition of recombinant human full length His-tagged ARG expressed in Baculovirus at 1 uM relative to control', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000201', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3nc(C)nc4ccsc34)n[nH]c2C1(C)C)c5ccccc5', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3817726', 'document_journal': 'J. Med. Chem.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3128043', 'parent_molecule_chembl_id': 'CHEMBL3128043', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '>', 'published_type': 'INH', 'published_units': '%', 'published_value': '75', 'qudt_units': 'http://qudt.org/vocab/unit#Percent', 'record_id': 2783846, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'Inhibition', 'standard_units': '%', 'standard_value': '75', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000187'}, {'activity_comment': None, 'activity_id': 16621477, 'assay_chembl_id': 'CHEMBL3820470', 'assay_description': 'Inhibition of ARG (unknown origin) incubated for 1 hr by spectrophotometric analysis', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'CN1C(=O)COc2c1cnc3ccc(Sc4nnc5c(F)cc(cn45)c6cnn(C)c6)cc23', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3817824', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL3818247', 'parent_molecule_chembl_id': 'CHEMBL3818247', 'pchembl_value': None, 'potential_duplicate': None, 'published_relation': '>', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '30000', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 2784915, 'src_id': 1, 'standard_flag': True, 'standard_relation': '>', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '30000', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}, {'activity_comment': None, 'activity_id': 16622192, 'assay_chembl_id': 'CHEMBL3820470', 'assay_description': 'Inhibition of ARG (unknown origin) incubated for 1 hr by spectrophotometric analysis', 'assay_type': 'B', 'bao_endpoint': 'BAO_0000190', 'bao_format': None, 'bao_label': None, 'canonical_smiles': 'CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35', 'data_validity_comment': None, 'document_chembl_id': 'CHEMBL3817824', 'document_journal': 'Bioorg. Med. Chem.', 'document_year': 2016, 'ligand_efficiency': None, 'molecule_chembl_id': 'CHEMBL388978', 'parent_molecule_chembl_id': 'CHEMBL388978', 'pchembl_value': '7.12', 'potential_duplicate': None, 'published_relation': '=', 'published_type': 'IC50', 'published_units': 'nM', 'published_value': '75.9', 'qudt_units': 'http://www.openphacts.org/units/Nanomolar', 'record_id': 2783100, 'src_id': 1, 'standard_flag': True, 'standard_relation': '=', 'standard_type': 'IC50', 'standard_units': 'nM', 'standard_value': '75.9', 'target_chembl_id': 'CHEMBL4014', 'target_organism': 'Homo sapiens', 'target_pref_name': 'Tyrosine-protein kinase ABL2', 'target_tax_id': '9606', 'uo_units': 'UO_0000065'}]
In [10]:
import xmltodict
In [11]:
# next, we are retrieving details from the assay the activity was measured in
# we keep binding and functional assays
# compounds of 10nM or better are considered as actives
# compounds of 10mycroM or worse are considered as inactives
chembl.assay.set_format('xml')
selected_actives = []
selected_decoys = []
for i in range(len(chembl_abl_activities)):
    x = chembl_abl_activities[i]
    ID = (x['assay_chembl_id'])
    details = chembl.assay.get(ID)
    d=xmltodict.parse(details)
    if(int(d['assay']['confidence_score']) == 9):
        if (d['assay']['assay_type'] in ['B','F']):
            if str(x['standard_units']) == 'nM':
                if float(x['standard_value']) < 10:
                    selected_actives.append(x['canonical_smiles'])
                elif float(x['standard_value']) > 10000:
                    selected_decoys.append(x['canonical_smiles'])
#selected_actives = set(selected_actives)            
print (len(selected_actives), len(selected_decoys)) 
selected_actives = set(selected_actives)
with open("ABL_smi","w") as fh:
    count = 0
    for e in selected_actives:
        print(e)
        count+=1
        fh.write(e + "\n")

14 2
COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl
CSc1cccc(Nc2ncc3C=C(C(=O)N(C)c3n2)c4c(Cl)cccc4Cl)c1
CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5cnccn45)n(C)n3)cc2C(F)(F)F)CC1
CN1CCN(Cc2ccc(cc2)C(=O)Nc3ccc(C)c(Nc4nccc(n4)c5cccnc5)c3)CC1
Cc1nc(Nc2ncc(s2)C(=O)Nc3c(C)cccc3Cl)cc(n1)N4CCN(CCO)CC4
CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5cccnn45)n(C)n3)cc2C(F)(F)F)CC1
CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc4cncc5nccn45)cc2C(F)(F)F)CC1
CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc3ccc(C)c(c3)C#Cc4cnc5cccnn45)CC1
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1
CN1CCN(CC1)c2cc(Nc3cc(C)[nH]n3)nc(Sc4ccc(NC(=O)C5CC5)cc4)n2
In [ ]: